Breaking Barriers: New Frontiers in Immunotherapy for Resistant Cancers

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ORIGINAL RESEARCH

Published on 21 Nov 2025

Efficacy of neoadjuvant pembrolizumab combined with paclitaxel and cisplatin in locally advanced oropharyngeal and hypopharyngeal squamous cell carcinoma: a retrospective study

Shupin Tang
Gongbiao Lin
Xiaobo Wu
Zhihong Chen

doi 10.3389/fimmu.2025.1690935

117 views

ORIGINAL RESEARCH

Published on 22 Sep 2025

Efficacy and safety of immune checkpoint inhibitor rechallenge therapy in the treatment of advanced acquired immune-resistant non-small cell lung cancer: a retrospective study

Jian Wang
Qijia Gao
Jianxin Chen

doi 10.3389/fonc.2025.1621860

1,275 views

MINI REVIEW

Published on 11 Sep 2025

Targeting tumor microenvironmental barriers to enhance immunogenic cell death in solid tumors

Jifeng Zhang
Wei Han
Mingchen Zhang
Yingjie Yi
Mei Long

doi 10.3389/fimmu.2025.1672601

1,273 views
1 citation

CASE REPORT

Published on 01 Sep 2025

Case Report: Durable complete response to antigen-specific cytotoxic T lymphocyte therapy in advanced EGFR-TKI resistant lung adenocarcinoma: a case of adoptive cellular immunotherapy overcoming acquired targeted resistance

Chenghao Fu
Chengyu Bian
Weiyou Zhu
Haonan Du
Linrui Han
Jian Zhu
Jun Wang
Lei Cao

doi 10.3389/fimmu.2025.1637165

1,722 views

REVIEW

Published on 22 Jul 2025

Unveiling mitochondrial transfer in tumor immune evasion: mechanisms, challenges, and clinical implications

Ruoyan Liu
Wenhui Shan
Zhening Wang
Hong Wang
Chunyan Li
Lei Yang
Rui Guo

doi 10.3389/fimmu.2025.1625814

3,753 views
1 citation

REVIEW

Published on 15 May 2025

Advances in neoantigen-based immunotherapy for head and neck squamous cell carcinoma: a comprehensive review

Manzhu Jiang
Jiefu Li
Jianhua Wei
Xuerong Yang
Weiqi Wang

doi 10.3389/fonc.2025.1593048

2,593 views

CASE REPORT

Published on 19 Mar 2025

Efficacy of combined immunotherapy and targeted therapy in overcoming barriers to postoperative recurrence in squamous subtype anaplastic thyroid carcinoma with abscess: a case report and literature review

Shuyun Jiang
Xiaowu Wang
Zhijun Ma

doi 10.3389/fonc.2025.1477954

1,657 views

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Frontiers in Oncology

Cancer Immunity and Immunotherapy

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Frontiers in Immunology
- Cancer Immunity and Immunotherapy
- 5.9 impact factor
- 10.8 citescore

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