Pharmacology of Natural Products against Neurodegenerative Disorders

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Articles

ORIGINAL RESEARCH

Published on 25 Sep 2025

The volatile oil of Acorus tatarinowii schott significantly attenuates neuroinflammatory damage in a rat model of tourette syndrome by inhibiting the p38 MAPK/NLRP3/STAT3 signaling pathway

Xing Wei
Kexin Sun
Peng Feng
Shuang Huang
Bing Jiang
Min Cui
Yuanhuan Chen
Fuchun Xue
Yuezhen He
7 more
Zhenggang Shi

doi 10.3389/fphar.2025.1540092

463 views

REVIEW

Published on 24 Sep 2025

Pharmacological mechanisms and therapeutic prospects of plant metabolites from traditional Chinese medicine in regulating programmed cell death in Alzheimer’s disease

Pengyu Pan
Tengyu Zhao
Jian Zhang
Yuhan Zhou
Xinyue Zhang
Quan Li
Yanyan Zhou

doi 10.3389/fphar.2025.1605214

467 views

REVIEW

Accepted on 23 Sep 2025

Anti-inflammatory Effect of Curcumin on Neurological Disorders: A Narrative Review

Baoyin Zhou
Binbin Hu

doi 10.3389/fphar.2025.1658115

379 views

ORIGINAL RESEARCH

Published on 29 Aug 2025

Systems pharmacology identifies ajugol-mediated NF-κB/caspase-3 inhibition and isoacteoside-driven p62/mTOR-mediated autophagy as key mechanisms of Rehmanniae Radix and its processed form in Alzheimer’s treatment

Xiang Han
Xianglong Meng
Yuhui Wu
Wei Xia
Simin Xue
Xiaoqin Liu
Chenzi Lyu
Ziang Li
Xiaoning Yan
1 more
Shuosheng Zhang

doi 10.3389/fphar.2025.1644847

1,231 views

ORIGINAL RESEARCH

Published on 28 Aug 2025

Spirodelae Herba ethanol extract attenuates neurotoxicity in hippocampal cells and improves scopolamine-induced cognitive impairment in mice

Yun Hee Jeong
YeonGyun Jung
Wei Li
Hye Jin Yang
You-Chang Oh
Jong-Sup Bae

doi 10.3389/fphar.2025.1638068

1,035 views

SYSTEMATIC REVIEW

Published on 11 Jul 2025

Preclinical evidence and potential mechanisms of tanshinone ⅡA on cognitive function in animal models of Alzheimer’s disease: a systematic review and meta-analysis

Yuanhang Rong
Qinqing Li
Yuzhong Du
Wenting Wang
Wenna Su
Junlong Zhang
Wenbin He

doi 10.3389/fphar.2025.1603861

1,268 views

ORIGINAL RESEARCH

Published on 04 Jul 2025

Intranasal administration of Ganoderma lucidum-derived exosome-like nanovesicles ameliorates cognitive impairment by reducing inflammation in a mouse model of Alzheimer’s disease

Xue Mi
Xinglin Ruan
Renyi Lin
Shuxin Huang
Ping Cai
Xiaochun Chen
Jiangfeng Liao
Xiaoman Dai

doi 10.3389/fphar.2025.1572771

2,005 views

REVIEW

Published on 27 Jun 2025

Preclinical and experimental evidence of salvianolic acid B in the treatment of neurological diseases

Shijun Bi
Shibing Liu
Kunyuan Zhu
Dandan Gao
Ligang Chen
Chunyong Yu
Guobiao Liang

doi 10.3389/fphar.2025.1606146

1,709 views

MINI REVIEW

Published on 24 Jun 2025

Research on the effects of GLP-1 receptor agonists in treating cognitive dysfunction and gait disorders in elderly patients with diabetes

Yang Yang
Lifeng Chen
Yanjun Zhang
Wenqian Fu
Dandan Liu
Tianyu Jiang

doi 10.3389/fphar.2025.1607443

1,369 views

REVIEW

Published on 23 Jun 2025

Unveiling the therapeutic potential of natural products in Alzheimer’s disease: insights from in vitro, in vivo, and clinical studies

Nahida Aktary
Yerim Jeong
Seungji Oh
Yeju Shin
Yoonsoo Sung
Muntajin Rahman
Livia Ramos Santiago
Jinwon Choi
Han Gyeul Song
3 more
Bonglee Kim

doi 10.3389/fphar.2025.1601712

3,810 views
2 citations

REVIEW

Published on 18 Jun 2025

Therapeutic potential of natural products in ischemic stroke: targeting angiogenesis

WenQiang Li
E. Liu
YiHao Zhou
ZhiChao Liao
DongYan Wang

doi 10.3389/fphar.2025.1579172

2,002 views

ORIGINAL RESEARCH

Published on 11 Jun 2025

Neuroprotective potential of quercetin in Alzheimer’s disease: targeting oxidative stress, mitochondrial dysfunction, and amyloid-β aggregation

Mohd Adnan
Arif Jamal Siddiqui
Fevzi Bardakci
Malvi Surti
Riadh Badraoui
Mitesh Patel

doi 10.3389/fphar.2025.1593264

2,490 views
1 citation

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Frontiers in Pharmacology

Ethnopharmacology
Neuropharmacology

Participating Journals

Frontiers in Neuroscience
- Neuropharmacology
- 3.2 impact factor
- 6.6 citescore

Manuscripts can be submitted to this Research Topic via the main journal or any other participating journal.

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Articles

The volatile oil of Acorus tatarinowii schott significantly attenuates neuroinflammatory damage in a rat model of tourette syndrome by inhibiting the p38 MAPK/NLRP3/STAT3 signaling pathway

Pharmacological mechanisms and therapeutic prospects of plant metabolites from traditional Chinese medicine in regulating programmed cell death in Alzheimer’s disease

Anti-inflammatory Effect of Curcumin on Neurological Disorders: A Narrative Review

Systems pharmacology identifies ajugol-mediated NF-κB/caspase-3 inhibition and isoacteoside-driven p62/mTOR-mediated autophagy as key mechanisms of Rehmanniae Radix and its processed form in Alzheimer’s treatment

Spirodelae Herba ethanol extract attenuates neurotoxicity in hippocampal cells and improves scopolamine-induced cognitive impairment in mice

Preclinical evidence and potential mechanisms of tanshinone ⅡA on cognitive function in animal models of Alzheimer’s disease: a systematic review and meta-analysis

Intranasal administration of Ganoderma lucidum-derived exosome-like nanovesicles ameliorates cognitive impairment by reducing inflammation in a mouse model of Alzheimer’s disease

Preclinical and experimental evidence of salvianolic acid B in the treatment of neurological diseases

Research on the effects of GLP-1 receptor agonists in treating cognitive dysfunction and gait disorders in elderly patients with diabetes

Unveiling the therapeutic potential of natural products in Alzheimer’s disease: insights from in vitro, in vivo, and clinical studies

Therapeutic potential of natural products in ischemic stroke: targeting angiogenesis

Neuroprotective potential of quercetin in Alzheimer’s disease: targeting oxidative stress, mitochondrial dysfunction, and amyloid-β aggregation

Frontiers in Pharmacology

Ethnopharmacology

Neuropharmacology

Participating Journals

Frontiers in Neuroscience

Neuropharmacology