Pharmacology of Natural Products against Neurodegenerative Disorders

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Articles

ORIGINAL RESEARCH

Published on 25 Nov 2025

Allocryptopine, tetrahydropalmatine, and tetrahydroberberine N-oxide alkaloids alleviate cellular stress by modulating calcium homeostasis and the MAPK and akt/GSK-3β/tau signaling pathways

Serap Nigdelioglu Dolanbay
Belma Aslim

doi 10.3389/fphar.2025.1589390

321 views

REVIEW

Published on 08 Oct 2025

Anti-inflammatory effect of curcumin on neurological disorders: a narrative review

Baoyin Zhou
Binbin Hu

doi 10.3389/fphar.2025.1658115

1,823 views

ORIGINAL RESEARCH

Published on 25 Sep 2025

The volatile oil of Acorus tatarinowii schott significantly attenuates neuroinflammatory damage in a rat model of tourette syndrome by inhibiting the p38 MAPK/NLRP3/STAT3 signaling pathway

Xing Wei
Kexin Sun
Peng Feng
Shuang Huang
Bing Jiang
Min Cui
Yuanhuan Chen
Fuchun Xue
Yuezhen He
7 more
Zhenggang Shi

doi 10.3389/fphar.2025.1540092

1,240 views

REVIEW

Published on 24 Sep 2025

Pharmacological mechanisms and therapeutic prospects of plant metabolites from traditional Chinese medicine in regulating programmed cell death in Alzheimer’s disease

Pengyu Pan
Tengyu Zhao
Jian Zhang
Yuhan Zhou
Xinyue Zhang
Quan Li
Yanyan Zhou

doi 10.3389/fphar.2025.1605214

1,683 views

ORIGINAL RESEARCH

Published on 29 Aug 2025

Systems pharmacology identifies ajugol-mediated NF-κB/caspase-3 inhibition and isoacteoside-driven p62/mTOR-mediated autophagy as key mechanisms of Rehmanniae Radix and its processed form in Alzheimer’s treatment

Xiang Han
Xianglong Meng
Yuhui Wu
Wei Xia
Simin Xue
Xiaoqin Liu
Chenzi Lyu
Ziang Li
Xiaoning Yan
1 more
Shuosheng Zhang

doi 10.3389/fphar.2025.1644847

2,017 views

ORIGINAL RESEARCH

Published on 28 Aug 2025

Spirodelae Herba ethanol extract attenuates neurotoxicity in hippocampal cells and improves scopolamine-induced cognitive impairment in mice

Yun Hee Jeong
YeonGyun Jung
Wei Li
Hye Jin Yang
You-Chang Oh
Jong-Sup Bae

doi 10.3389/fphar.2025.1638068

1,375 views

SYSTEMATIC REVIEW

Published on 11 Jul 2025

Preclinical evidence and potential mechanisms of tanshinone ⅡA on cognitive function in animal models of Alzheimer’s disease: a systematic review and meta-analysis

Yuanhang Rong
Qinqing Li
Yuzhong Du
Wenting Wang
Wenna Su
Junlong Zhang
Wenbin He

doi 10.3389/fphar.2025.1603861

1,761 views

ORIGINAL RESEARCH

Published on 04 Jul 2025

Intranasal administration of Ganoderma lucidum-derived exosome-like nanovesicles ameliorates cognitive impairment by reducing inflammation in a mouse model of Alzheimer’s disease

Xue Mi
Xinglin Ruan
Renyi Lin
Shuxin Huang
Ping Cai
Xiaochun Chen
Jiangfeng Liao
Xiaoman Dai

doi 10.3389/fphar.2025.1572771

2,982 views
2 citations

REVIEW

Published on 27 Jun 2025

Preclinical and experimental evidence of salvianolic acid B in the treatment of neurological diseases

Shijun Bi
Shibing Liu
Kunyuan Zhu
Dandan Gao
Ligang Chen
Chunyong Yu
Guobiao Liang

doi 10.3389/fphar.2025.1606146

2,436 views

MINI REVIEW

Published on 24 Jun 2025

Research on the effects of GLP-1 receptor agonists in treating cognitive dysfunction and gait disorders in elderly patients with diabetes

Yang Yang
Lifeng Chen
Yanjun Zhang
Wenqian Fu
Dandan Liu
Tianyu Jiang

doi 10.3389/fphar.2025.1607443

1,888 views
1 citation

REVIEW

Published on 23 Jun 2025

Unveiling the therapeutic potential of natural products in Alzheimer’s disease: insights from in vitro, in vivo, and clinical studies

Nahida Aktary
Yerim Jeong
Seungji Oh
Yeju Shin
Yoonsoo Sung
Muntajin Rahman
Livia Ramos Santiago
Jinwon Choi
Han Gyeul Song
3 more
Bonglee Kim

doi 10.3389/fphar.2025.1601712

6,478 views
4 citations

REVIEW

Published on 18 Jun 2025

Therapeutic potential of natural products in ischemic stroke: targeting angiogenesis

WenQiang Li
E. Liu
YiHao Zhou
ZhiChao Liao
DongYan Wang

doi 10.3389/fphar.2025.1579172

3,258 views
2 citations

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Frontiers in Pharmacology

Ethnopharmacology
Neuropharmacology

Other participating journals

Frontiers in Neuroscience
- Neuropharmacology
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- 6.6 citescore

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Articles

Allocryptopine, tetrahydropalmatine, and tetrahydroberberine N-oxide alkaloids alleviate cellular stress by modulating calcium homeostasis and the MAPK and akt/GSK-3β/tau signaling pathways

Anti-inflammatory effect of curcumin on neurological disorders: a narrative review

The volatile oil of Acorus tatarinowii schott significantly attenuates neuroinflammatory damage in a rat model of tourette syndrome by inhibiting the p38 MAPK/NLRP3/STAT3 signaling pathway

Pharmacological mechanisms and therapeutic prospects of plant metabolites from traditional Chinese medicine in regulating programmed cell death in Alzheimer’s disease

Systems pharmacology identifies ajugol-mediated NF-κB/caspase-3 inhibition and isoacteoside-driven p62/mTOR-mediated autophagy as key mechanisms of Rehmanniae Radix and its processed form in Alzheimer’s treatment

Spirodelae Herba ethanol extract attenuates neurotoxicity in hippocampal cells and improves scopolamine-induced cognitive impairment in mice

Preclinical evidence and potential mechanisms of tanshinone ⅡA on cognitive function in animal models of Alzheimer’s disease: a systematic review and meta-analysis

Intranasal administration of Ganoderma lucidum-derived exosome-like nanovesicles ameliorates cognitive impairment by reducing inflammation in a mouse model of Alzheimer’s disease

Preclinical and experimental evidence of salvianolic acid B in the treatment of neurological diseases

Research on the effects of GLP-1 receptor agonists in treating cognitive dysfunction and gait disorders in elderly patients with diabetes

Unveiling the therapeutic potential of natural products in Alzheimer’s disease: insights from in vitro, in vivo, and clinical studies

Therapeutic potential of natural products in ischemic stroke: targeting angiogenesis

Frontiers in Pharmacology

Ethnopharmacology

Neuropharmacology

Other participating journals

Frontiers in Neuroscience

Neuropharmacology