The Quintuple of Climate Change, Landscape Modification, Globalization, Pathogen Adaptation and Outbreaks

In the wake of the COVID-19 pandemic, several countries have revamped their outbreak preparedness structures, but the dynamics behind infection transmission remain elusive, underscoring the need for further exploration to prevent future outbreaks effectively. Factors such as globalization enhance human mobility, heightening cross-border infection risks, while climate change alters the agricultural landscape and the spread of tropical diseases, particularly vector-borne illnesses. Additionally, environmental changes like deforestation bring humans closer to wildlife, facilitating pathogen transfers between species. Another critical factor, antimicrobial resistance, continues to evolve, leading to a "silent pandemic". Understanding these interconnected dynamics—climate change, landscape modification, globalization, pathogen adaptation, and their impacts on outbreaks—is crucial for advancing control and prevention strategies.

This Research Topic aims to broaden our comprehension of how interconnected factors like climate change, globalization, landscape modifications, and pathogen adaptations influence the emergence and spread of infectious diseases. Reviewing and addressing the gaps highlighted by the WHO's list of priority pathogens, this Research Topic will contribute to the proactive monitoring and readiness against potential new pathogens and outbreaks, especially in diverse geographical contexts which may face unique threats.

To gather further insights in the dynamics shaping global health risks, we welcome articles addressing, but not limited to, the following themes:

• Epidemiology and the impact of environmental changes on disease spread
• Origin and evolution biology of pathogens
• Pathogen-host interactions and adaptation strategies
• Vector biology and its relation to global health
• Pathogen ecology within changing landscapes
• Pathobiology and transmission biology of infections
• Strategies for infection control and prevention
• Immunology and vaccine development against emergent pathogens
• Advances in diagnosis, treatment, and resistance management
• Preventive medicine integration with public health and economics
• Multidisciplinary approaches to one health and planet health

We welcome submission of the following article types: Hypothesis & Theory, Methods, Mini Review, Opinion, Original Research, Perspective, Review, Technology & Code, Case Report, Classification, Clinical Trial, and Systematic Review.

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Classification
• Clinical Trial
• Community Case Study
• Conceptual Analysis
• Curriculum, Instruction, and Pedagogy
• Data Report
• Editorial
• ... View all formats

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Article types

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Classification
• Clinical Trial
• Community Case Study
• Conceptual Analysis
• Curriculum, Instruction, and Pedagogy
• Data Report
• Editorial
• FAIR² Data
• FAIR² DATA Direct Submission
• General Commentary
• Hypothesis and Theory
• Methods
• Mini Review
• Opinion
• Original Research
• Perspective
• Policy and Practice Reviews
• Policy Brief
• Review
• Study Protocol
• Systematic Review
• Technology and Code

Keywords: The quintuple of climate change, landscape modification, globalization, pathogen adaptation and outbreaks

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.