Innovative solutions for host immunomodulation

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About this Research Topic

Submission deadlines

  1. Manuscript Submission Deadline 14 June 2026

  2. This Research Topic is currently accepting articles.

Background

Recent advances in multidisciplinary technologies have increased our understanding of host immunobiology, particularly the dynamic interplay between pathogens (or transformed cells) and host immune cells. This interaction is mediated through a wide range of molecular signals that influence the outcome of infection and inflammation. A critical opportunity now lies in using this knowledge to precisely modulate immune responses and limit collateral damage.

This Research Topic will highlight new knowledge in the area of host immunobiology and explore novel therapeutically viable solutions for the control of debilitating diseases.

The Research Topic will address the latest understanding and knowledge of immunological basis of infectious diseases, inflammatory conditions, and cancer.

Contributions will focus on how these cutting-edge immunological findings are being harnessed to modulate the host immune system and design next-generation treatments for the control and prevention of these diseases. Latest trends in advanced approaches, technologies, and interpretations will be covered in articles throughout this Research Topic. This Research Topic aims to highlight new treatment avenues or developing new therapies for debilitating infectious diseases, inflammatory conditions, and cancer.

We invite the submission of original research, review articles, and brief research reports focused on bridging our mechanistic understanding of host immunobiology and the development of effective interventions. We also invite the submission of method articles focused on newer technologies for evaluating host susceptibility and immune responses to pathogens, ligands, and environmental stimuli.

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

  • Brief Research Report
  • Case Report
  • Classification
  • Clinical Trial
  • Editorial
  • FAIR² Data
  • FAIR² DATA Direct Submission
  • General Commentary
  • Hypothesis and Theory

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Keywords: Biochemical technologies, Multi-omics, Host immune system, Immune cells, Immune molecules, Host immunobiology, Translational research, Systems biology, Host-pathogen interactions, Innate immunity, Modeling, Multidisciplinary approaches, Immunomodulation, Therapeutic development

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Topic editors

Manuscripts can be submitted to this Research Topic via the main journal or any other participating journal.

Impact

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