Advances in Pediatric Arrhythmia: Pathophysiology, Diagnostics, and Therapy

Research into pediatric arrhythmia is gaining increasing attention as more is understood about the distinctive nature of this condition in children. Unlike adult arrhythmias, pediatric arrhythmias present atypical clinical manifestations, diverse underlying causes, and different electrocardiogram patterns. These variations are often influenced by congenital conditions, infections, or electrolyte imbalances. While medical technology and therapeutic interventions have improved patient outcomes, there are persistent challenges related to diagnosis, management, and lifelong care for affected children. Significant studies have attempted to delineate the pathophysiological and genetic basis of arrhythmias in children and have underscored the need for a deeper exploration of the molecular and cellular mechanisms involved.


This Research Topic aims to explore and promote innovations in understanding and treating pediatric arrhythmia through multidisciplinary collaboration and cutting-edge research. By focusing on a wide range of avenues including pathophysiology, genetics, diagnostic techniques, and therapeutic strategies, this topic seeks to address the existing gaps and challenges in the field. Key objectives include the investigation of genetic and developmental contributors to arrhythmia, the development of AI-driven diagnostic tools, and the application of personalized medicine in therapeutic approaches. The research will also explore the transition of care strategies as patients move from childhood into adulthood.

To gather further insights into the scope of pediatric arrhythmia, we welcome original research, reviews, or case reports addressing, but not limited to, the following themes:
• Investigation of genetic and developmental contributors to arrhythmia
• Advances in understanding the molecular and cellular mechanisms involved
• Development and application of Big Data and AI tools in arrhythmia diagnosis
• Fetal electrocardiogram monitoring techniques and methods for early detection
• Interventional advancements, including new energy or new materials
• Pharmacological treatments and personalized medicine approaches
• Unique clinical cases and innovative approaches in care
• Long-term management strategies in different ages for transitioning from childhood to teenagers, and from pediatric to adult stages
• Findings from recent clinical trials and implications for treatment guidelines

By consolidating research and clinical perspectives, this Research Topic aims to enhance the understanding and management of pediatric arrhythmia, ultimately leading to improved patient outcomes and quality of life.

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Clinical Trial
• Editorial
• FAIR² Data
• General Commentary
• Hypothesis and Theory
• Methods
• Mini Review
• ... View all formats

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Article types

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Clinical Trial
• Editorial
• FAIR² Data
• General Commentary
• Hypothesis and Theory
• Methods
• Mini Review
• Opinion
• Original Research
• Perspective
• Policy and Practice Reviews
• Review
• Study Protocol
• Systematic Review
• Technology and Code

Keywords: Pediatric arrhythmia, genetic, molecular mechanisms, AI diagnosis, personalized medicine, fetal ECG, interventional therapies, long-term management, transition of care, pathophysiology, diagnostic techniques, therapeutic strategies, clinical trials

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.