Dietary Fibre and Type 2 Diabetes Risk

The association between dietary fibre intake and the development and management of type 2 diabetes has garnered widespread interest in nutrition and metabolic health research. Growing evidence suggests that both soluble and insoluble fibres can play a significant role in modulating glycemic control, insulin sensitivity, and other metabolic risk factors, yet the exact biological mechanisms remain incompletely understood. Recent studies have pointed to potential roles for gut microbiota, short-chain fatty acids, inflammation, and cellular signaling pathways as mediators of fibre’s effects on diabetes risk.

This Research Topic aims to advance our understanding of how dietary fibre influences the onset and progression of type 2 diabetes, with a focus on mechanistic insights and risk factor modification. We seek to highlight multidisciplinary contributions that explore not only epidemiological and clinical aspects, but also molecular, microbiological, and physiological pathways involved.

We welcome a broad spectrum of original research, reviews, and meta-analyses that address, but are not limited to, the following themes:

• Differences in the metabolic effects of soluble vs. insoluble fibre
• Dietary fibre’s impact on glycemic control and insulin resistance
• Modulation of gut microbiota and its metabolic consequences
• Fibre, inflammation, and oxidative stress in type 2 diabetes
• Interactions between dietary fibre and diabetes medications or overall dietary patterns

Topic Editor Evangelia Kotzakioulafi is employed on a temporary contract by Nestle Institute of Health Sciences, Nestle Research, until August 2026. All other Topic Editors declare no competing interests with regards to the Research Topic subject.

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Classification
• Clinical Trial
• Community Case Study
• Conceptual Analysis
• Data Report
• Editorial
• FAIR² Data
• ... View all formats

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Article types

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Classification
• Clinical Trial
• Community Case Study
• Conceptual Analysis
• Data Report
• Editorial
• FAIR² Data
• General Commentary
• Hypothesis and Theory
• Methods
• Mini Review
• Opinion
• Original Research
• Perspective
• Policy and Practice Reviews
• Registered Report
• Review
• Systematic Review
• Technology and Code

Keywords: dietary fiber, type 2 diabetes, glycemic control, insulin resistance, insulin sensitivity, soluble fiber, insoluble fiber, gut microbiota, short-chain fatty acids, SCFAs, inflammation, oxidative stress, metabolic health, glucose metabolism, glucose homeostasis, metaboli

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.