Advances in perinatal and neonatal clinical pharmacology

The perinatal period is a critical stage in the development of the newborn; pharmacological interventions during this period can have a significant impact on neonatal health outcomes.

In this topic, we would like to explore all aspects of human perinatal pharmacology, including pharmacoepidemiology, pharmacokinetics and -dynamics as well as efficacy and safety aspects of medicines administered to the mother during pregnancy, lactation and to the neonate.

Clinical pharmacology techniques such as pharmacogenomics and population pharmacokinetics can be invaluable in determining optimal dosing regimens, minimizing the risk of adverse drug reactions, and improving drug efficacy in neonatal populations. Therefore, we would especially like to highlight the utility of advanced clinical pharmacology methods in this targeted population and studies on the interaction between pharmacological and non-pharmacological interventions.

In this exciting Research Topic, we focus on perinatal and neonatal clinical pharmacology as well as the impact of pharmacological interventions on the human fetus and newborn. We welcome original research and review articles covering the following themes:

• Benefit-risk assessments of medications for the developing fetus and neonate
• The impact of pharmacological therapy on long-term health
• Studies identifying the challenges and opportunities associated with pharmacological interventions in the neonatal population
• Ethical considerations of medicines used during pregnancy and lactation
• Novel pharmacological approaches for the prevention and treatment of neonatal diseases

We invite authors from a range of disciplines, including neonatology, pharmacology, pediatrics, obstetrics, and clinical pharmacology to submit their work for consideration.

Keywords: perinatal medicine, neonatal health, perinatal period

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.