Corrigendum: Prevalence of iron-deficiency anemia in pregnant women with various thalassemia genotypes: thoughts on iron supplementation in pregnant women with thalassemia genes

The value of Hb and MCH were compared among different groups. (1) ^aThe Hb level of Normal group was higher than those of α^QSα/αα, –^SEA/αα, –α^3.7/–α^3.7, –α^3.7/–α^4.2, –α^4.2/–α^4.2, α^WSα/–α^3.7, α^WSα/–α^4.2, α^QSα/–α^3.7, α^QSα/–α^4.2, –^SEA/α^WSα, –^SEA/–α^3.7, –^SEA/–α^4.2, β^CD17(A>T)/β, β^{CD41/42(−TTCT)}/β, β^CD71/72(+A)/β, β^{IVS − II − 654(C>T)}/β, and β^−28(A>G)/β groups (P < 0.05); ^bthe MCH level of Normal group was higher than those of all other groups (P < 0.05). (2) Among α-thalassemia silent genotypes, ^cthe Hb level of α^QSα/αα was lower than those of –α^3.7/αα, –α^4.2/αα, α^WSα/αα (P < 0.05); ^dthe MCH level of α^WSα/αα was higher than those of –α^3.7/αα, –α^4.2/αα, α^QSα/αα and α^CSα/αα (P < 0.05); ^ethe MCH level of α^QSα/αα was lower than those of –α^3.7/αα, –α^4.2/αα, and α^CSα/αα (P < 0.05). (3) Among α-thalassemia minor genotypes, ^fthe Hb levels of –^SEA/αα, –α^3.7/–α^3.7, –α^3.7/–α^4.2, –α^4.2/–α^4.2 were lower than those of α^WSα/–α^3.7, α^WSα/–α^4.2, α^WSα/α^WSα, while was higher than those of α^QSα/–α^3.7 groups (P < 0.05); ^gthe Hb levels of α^WSα/–α^3.7, α^WSα/–α^4.2, α^WSα/α^WSα, α^WSα/α^QSα were higher than those of α^QSα/–α^3.7, α^QSα/–α^4.2 (P < 0.05); ^hthe MCH level of –^SEA/αα was higher than that of α^QSα/–α^4.2, while was lower than those of –α^3.7/–α^3.7, –α^3.7/–α^4.2, –α^4.2/–α^4.2, α^WSα/–α^3.7, α^WSα/–α^4.2, α^WSα/α^WSα, α^WSα/α^QSα (P < 0.05); ⁱthe MCH levels of –α^3.7/–α^3.7, –α^3.7/–α^4.2, –α^4.2/–α^4.2 were lower than those of α^WSα/–α^3.7, α^WSα/–α^4.2, α^WSα/α^WSα, while were higher than those of α^QSα/–α^3.7, α^QSα/–α^4.2 (P < 0.05); ^jthe MCH level of α^WSα/α^QSα was lower than that of α^WSα/α^WSα (P < 0.05); ^kthe MCH levels of α^QSα/–α^3.7, α^QSα/–α^4.2 were lower that those of α^WSα/–α^3.7, α^WSα/–α^4.2, α^WSα/α^WSα, α^WSα/α^QSα (P < 0.05). (4) Among the α-thalassemia intermediate genotypes, ^lthe Hb and MCH levels of –^SEA/α^WSα were lower than those of –^SEA/–α^3.7, and –^SEA/–α^4.2 (P < 0.05); (5) Among the β-thalassemia minor genotypes, ^mthe Hb and MCH levels of β^−28(A>G)/β, β^{CD26(GAG>AAG)}/β were higher than those of β^CD17(A>T)/β, β^{CD41/42(−TTCT)}/β, β^CD71/72(+A)/β, β^{IVS − II − 654(C>T)}/β (P < 0.05). ⁿnumber; PW, pregnant women; RBC, red blood cell; Hb, hemoglobin; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin.

Hb^{PF < 30}: The Hb levels in APW with ID (PF < 30 ng/mL). Hb^PF≥30: the Hb levels in APW without ID (PF ≥ 30 ng/mL). PF^*: the PF levels in APW without ID (PF ≥ 30 ng/mL). PF: the PF levels in all APW. –α^3.7(or4.2)/αα, –α^3.7/αα and –α^4.2/αα were combined into one group. α^CS(orQS)α/αα, α^CSα/αα and α^QSα/αα were combined into one group. –α^3.7(or4.2)/–α^3.7(or4.2): –α^3.7/–α^3.7, –α^3.7/–α^4.2, and –α^4.2/–α^4.2 were combined into one group. α^CS(orQS)α/–α^3.7(or4.2): α^CSα/–α^3.7, α^CSα/–α^4.2, α^QSα/–α^3.7, and α^QSα/–α^4.2 were combined into one group. α^WSα/–α^3.7(or4.2): α^WSα/–α^3.7, and α^WSα/–α^4.2 were combined into one group. –α^3.7(or4.2)/–^SEA: –α^3.7/–^SEA, and -α^4.2/–^SEA were combined into one group. β^T4/β: β^{IVS − II − 654(C>T)}/β, β^{CD41/42(−TTCT)}/β, β^CD17(A>T)/β, and β^CD71/72(+A)/β were combined into one group. ^aP < 0.05 vs. the group of −α^3.7(or4.2)/–^SEA. ^bP < 0.05 vs. the Normal group. ^cP < 0.05 vs. the groups of β^T4/β and β^−28(A>G)/β. ^dP < 0.05 vs. the group of β^T4/β. /: statistical analysis was performed when the sample size was greater than 5. Hb, hemoglobin; PF, plasma ferritin; APW, anemic pregnant women; ID, iron deficiency.