Frontiers in Aging Neuroscience

Original Research

Published on 18 Aug 2025

Risk prediction of recurrent ischemic stroke based on Carotid Plaque-RADS: construction and validation of a nomogram model

in Neuroinflammation and Neuropathy

Miao Qiao
Ting Zhou
Rui Wang
Yanhui Jiang
Huitao Liang
Lingcui Meng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1646916

2,953 views
4 citations

Original Research

Published on 18 Aug 2025

Accelerated midlife endocrine and bioenergetic brain aging in APOE4 females

in Alzheimer's Disease and Related Dementias

Tian Wang
Zisu Mao
Yuan Shang
Simona Merlini
Francesca Vitali
Jean-Paul Wiegand
Roberta Diaz Brinton

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1632877

4,284 views
2 citations

Original Research

Published on 18 Aug 2025

Age-related differences in the weighting of kinematic and contextual information during action prediction

in Neurocognitive Aging and Behavior

Elisa Ravizzotti
Alessandra Finisguerra
Gaia Bonassi
Carola Cosentino
Susanna Mezzarobba
Alessandro Botta
Martina Putzolu
Sara Terranova
Valentina Bianco
Laura Avanzino

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1622569

1,695 views
1 citation

Systematic Review

Published on 18 Aug 2025

Glutamate-associated research in Parkinson’s disease: a bibliometric analysis

in Cellular and Molecular Mechanisms of Brain-aging

Yan-Jun Chen
Ming-Rong Xie
Sheng-Qiang Zhou
Fang Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1569924

3,107 views

Original Research

Published on 18 Aug 2025

Accurate and robust prediction of Amyloid-β brain deposition from plasma biomarkers and clinical information using machine learning

in Alzheimer's Disease and Related Dementias

Jiayuan Xu
Andrew J. Doig
Sofia Michopoulou
Petroula Proitsi
Fumie Costen
The Alzheimer's disease neuroimaging initiative

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1559459

2,340 views

Review

Published on 15 Aug 2025

Naringenin as a neurotherapeutic agent in Alzheimer’s disease: epigenetic signatures, gut microbiota alterations, and molecular neuroprotection

in Alzheimer's Disease and Related Dementias

Zhenzhen Lai
Long Ke
Wei Zhao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1647967

4,829 views
7 citations

Review

Published on 15 Aug 2025

Artificial intelligence technologies for enhancing neurofunctionalities: a comprehensive review with applications in Alzheimer’s disease research

in Alzheimer's Disease and Related Dementias

Zhirong Gu
Bin Ge
Yuanyuan Wang
Yiping Gong
Mei Qi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1609063

4,759 views
2 citations

Mini Review

Published on 14 Aug 2025

Exploring efficient and effective mammalian models for Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Mitsunori Kayano

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1652754

3,343 views
1 citation

Original Research

Published on 14 Aug 2025

Neurofilament light chain concentration mediates the association between regional cortical thickness and Parkinson’s disease with excessive daytime sleepiness

in Parkinson’s Disease and Aging-related Movement Disorders

Jieyu Chen
Guoliang Jiang
Yongyun Zhu
Chunyu Liang
Chenxi Liu
Jianzhun Chen
Baiyuan Yang
Xinglong Yang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1645290

1,697 views
1 citation

Original Research

Published on 13 Aug 2025

Age- and sex-related differences in landmark recall following a virtual spatial navigation task

in Neurocognitive Aging and Behavior

Alexis N. Chargo
Cheryl L. Dahle
Naftali Raz
Ana M. Daugherty

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1602945

1,677 views

Original Research

Published on 13 Aug 2025

Combinations of multimodal neuroimaging biomarkers and cognitive test scores to identify patients with cognitive impairment

in Neurocognitive Aging and Behavior

Yuriko Nakaoku
Soshiro Ogata
Kiyotaka Nemoto
Chikage Kakuta
Eri Kiyoshige
Kanako Teramoto
Kiyomasa Nakatsuka
Gantsetseg Ganbaatar
Masafumi Ihara
Kunihiro Nishimura

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1650629

2,292 views

Original Research

Published on 13 Aug 2025

Gut dysbiosis is associated with increased blood–brain barrier permeability and cognitive impairment in elderlies with coronary heart disease

in Cellular and Molecular Mechanisms of Brain-aging

Lichao Di
Peiying Huang
Yeju He
Na Sun
Liwei Chi
Lining Huang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1640761

2,903 views
3 citations

Systematic Review

Published on 13 Aug 2025

The effect of transcranial direct current stimulation on static and dynamic posture control in the elderly: a systematic review and meta-analysis

in Neurocognitive Aging and Behavior

Yaru Wei
Peng Chen
Jianglong Zhan
Lulu Yin
Zhongqi Yu
Lin Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1645962

2,293 views

Perspective

Published on 12 Aug 2025

A model to address healthcare gaps and poor research participation in Hispanic patients with Parkinson's disease

in Parkinson’s Disease and Aging-related Movement Disorders

M. Felice Ghilardi
Alessandro Di Rocco
Jennifer Fearday
Donna Sperlakis
Maria Lima
Nora Vanegas-Arroyave
Elisa Tatti
Marcelo Arroyave
Evelyn Stevens
Denise Hernandez

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1610448

1,933 views

Original Research

Published on 12 Aug 2025

Relationship between the platelet-to-lymphocyte ratio and in-hospital mortality of ischemic stroke patients in the intensive care unit

in Neuroinflammation and Neuropathy

Guohua Liu
Ya Zhou
Hao Ding
Lin Chen
Lan Chen
Sufang Yang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1607332

2,007 views

Mini Review

Published on 12 Aug 2025

Seeking the neural basis of neuropsychiatric symptoms in dementia: neuroimaging findings and controversies

in Neurocognitive Aging and Behavior

Daichi Sone
Shunichiro Shinagawa

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1633309

1,969 views
1 citation

Original Research

Published on 12 Aug 2025

Local gyrification index and sulcal depth as imaging markers of cognitive decline in Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Yongsik Sim
Changmin Seo
Young-gun Lee
Byoung Seok Ye
Ilwoo Lyu
Beomseok Sohn

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1635861

2,292 views

Original Research

Published on 11 Aug 2025

Increased tau-induced inflammatory responses are associated with a greater degree of atherosclerosis in progressive supranuclear palsy

in Parkinson’s Disease and Aging-related Movement Disorders

Yi-Xin He
Rui Zhang
Chen Xie
Si-Fan Ji
Wen-Jing Deng
Jun-Fang Teng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1608631

2,155 views

Original Research

Published on 08 Aug 2025

Objective assessment of gait and posture symptoms in Parkinson’s disease using wearable sensors and machine learning

in Parkinson’s Disease and Aging-related Movement Disorders

Lingyan Ma
Shinuan Lin
Jianing Jin
Zhan Wang
Xuemei Wang
Zhonglue Chen
Yun Ling
Fei Zhang
Kang Ren
Tao Feng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1618764

2,540 views

Clinical Trial

Published on 08 Aug 2025

Improvement of neuropsychological and cognitive functions in older adults through transcranial vibroacoustic stimulation: a double blind, randomized, comparative trial

in Neurocognitive Aging and Behavior

Jang-Han Bae
Jae-Young Ha
Jai Jun Choung
Min-Woo Cho
Byung-In Oh
Kun Ho Lee
Young Chul Youn
SangYun Kim
Dong-Keun Song
Chang-Ho Shin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1526088

4,057 views
2 citations

Review

Published on 07 Aug 2025

Acupuncture modulates the microbiota-gut-brain axis: a new strategy for Parkinson’s disease treatment

in Parkinson’s Disease and Aging-related Movement Disorders

Zimo Zang
Fang Yang
Liang Qu
Minghui Ge
Liang Tong
Lihui Xue
Xiuye Sun
Ying Hai

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1640389

4,810 views
4 citations

Review

Published on 07 Aug 2025

Curcumin and neuroplasticity: epigenetic mechanisms underlying cognitive enhancement in aging and neurodegenerative disorders

in Cellular and Molecular Mechanisms of Brain-aging

Hao Jiao
Xiuying Wang
Dahui Zhang
Shengxue Zhou
Feng Gao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1592280

6,143 views
3 citations

Original Research

Published on 07 Aug 2025

Latent profile analysis of loneliness among elderly people in the community and its relationship with cognitive function

in Neurocognitive Aging and Behavior

Lei Yang
Rushi Yang
Tiantian Liu
Jinfeng Wang
Bo Wang
Fengxue Zhao
Yue Zhang
Ping Zhang
Hao Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1574095

2,736 views

Original Research

Published on 06 Aug 2025

Neuroinflammation-mediated YKL-40 correlates with tau pathology and predicts longitudinal cognitive impairment and brain atrophy in Alzheimer’s disease, with hypertensive dependency

in Alzheimer's Disease and Related Dementias

Ya-Yu Wang
Man Zhang
Shu-Jian Chen
Wei Miao
Zhi-Xin Wang
Ya-Jun Zhou
Si-Qi Yu
Zhong-Wu Sun
Xia Zhou
Xian-Feng Yu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1630022

2,927 views
6 citations

7,808 articles

articles

Risk prediction of recurrent ischemic stroke based on Carotid Plaque-RADS: construction and validation of a nomogram model

Accelerated midlife endocrine and bioenergetic brain aging in APOE4 females

Age-related differences in the weighting of kinematic and contextual information during action prediction

Glutamate-associated research in Parkinson’s disease: a bibliometric analysis

Accurate and robust prediction of Amyloid-β brain deposition from plasma biomarkers and clinical information using machine learning

Naringenin as a neurotherapeutic agent in Alzheimer’s disease: epigenetic signatures, gut microbiota alterations, and molecular neuroprotection

Artificial intelligence technologies for enhancing neurofunctionalities: a comprehensive review with applications in Alzheimer’s disease research

Exploring efficient and effective mammalian models for Alzheimer’s disease

Neurofilament light chain concentration mediates the association between regional cortical thickness and Parkinson’s disease with excessive daytime sleepiness

Age- and sex-related differences in landmark recall following a virtual spatial navigation task

Combinations of multimodal neuroimaging biomarkers and cognitive test scores to identify patients with cognitive impairment

Gut dysbiosis is associated with increased blood–brain barrier permeability and cognitive impairment in elderlies with coronary heart disease

The effect of transcranial direct current stimulation on static and dynamic posture control in the elderly: a systematic review and meta-analysis

A model to address healthcare gaps and poor research participation in Hispanic patients with Parkinson's disease

Relationship between the platelet-to-lymphocyte ratio and in-hospital mortality of ischemic stroke patients in the intensive care unit

Seeking the neural basis of neuropsychiatric symptoms in dementia: neuroimaging findings and controversies

Local gyrification index and sulcal depth as imaging markers of cognitive decline in Alzheimer’s disease

Increased tau-induced inflammatory responses are associated with a greater degree of atherosclerosis in progressive supranuclear palsy

Objective assessment of gait and posture symptoms in Parkinson’s disease using wearable sensors and machine learning

Improvement of neuropsychological and cognitive functions in older adults through transcranial vibroacoustic stimulation: a double blind, randomized, comparative trial

Acupuncture modulates the microbiota-gut-brain axis: a new strategy for Parkinson’s disease treatment

Curcumin and neuroplasticity: epigenetic mechanisms underlying cognitive enhancement in aging and neurodegenerative disorders

Latent profile analysis of loneliness among elderly people in the community and its relationship with cognitive function

Neuroinflammation-mediated YKL-40 correlates with tau pathology and predicts longitudinal cognitive impairment and brain atrophy in Alzheimer’s disease, with hypertensive dependency