Frontiers in Bioengineering and Biotechnology

Original Research

Published on 09 Jul 2026

Efficient, complete biosynthesis of isoflavonoid calycosin-7-glucoside by metabolically engineered yeast cell factories

in Synthetic Biology

Weifeng Zhang
Mingyuan Xu
Linlin Wang
Xue Qiao
Song Yang
Yi Liu
Quanli Liu
Xuefeng Lu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1875470

603 views

Editorial

Accepted on 08 Jul 2026

Editorial: Advancements in microbial engineering for natural product synthesis

in Synthetic Biology

Cheng Li
Kai Li
Yuanyuan Huang

Frontiers in Bioengineering and Biotechnology

Review

Published on 08 Jul 2026

Beyond glucose: wearable and implantable biosensors for continuous monitoring of metabolic, hormonal, and inflammatory biomarkers in personalized cardiometabolic care

in Synthetic Biology

Hong Cai
Yehui He
Chaoyue Wang
Yiqun Zhao
Chunhui Yang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1885022

890 views

Perspective

Published on 06 Jul 2026

Synthetic biology and genome engineering in support of human, agricultural, and environmental security

in Synthetic Biology

Carolyn Riley Chapman
Julie Trolle
Dominika Daria Wawrzyniak
Jef D. Boeke
Ran Brosh

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1820360

977 views

Original Research

Accepted on 03 Jul 2026

Beyond Enzyme Engineering: Ordered enzyme immobilization drives enhanced productivity in vitro

in Synthetic Biology

Matthew Wong
Thomas Gediminas Neuman
MD Anarul Hoque
Sarah Moraïs
Edward Bayer
Georges Belfort
Mattheos Koffas

Frontiers in Bioengineering and Biotechnology

225 views

Hypothesis and Theory

Published on 30 Jun 2026

Chemical organizations as a conceptual tool: from synthetic biology to interdisciplinary systems and back

in Synthetic Biology

Tomas Veloz
Christian Jendreiko

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1801128

1,003 views

Review

Published on 30 Jun 2026

Bioinks in systems biology: integrating biomaterial design with cellular network modelling for predictive biofabrication

in Synthetic Biology

Inamul Hasan Madar
Jayant Pawar
Punitha Muruganantham
Syed Suhaib Ahmed
Vansh Vohra
Janakiraman Velayudam

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1854783

797 views

Original Research

Accepted on 29 Jun 2026

Interaction between crgA and wc-1b in carotenoid synthesis in Blakeslea trispora

in Synthetic Biology

Youai Dai
Renyue Gui
Jingyu Chen
Wei Luo

Frontiers in Bioengineering and Biotechnology

231 views

Original Research

Published on 29 Jun 2026

Microbial conversion of biodiesel waste for carotenoid production

in Synthetic Biology

Katherine R. Weber
Zoe Chu
Haley Desai
Nicholas Cox
Dragan Simovic
Julie A. Maupin-Furlow

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1851919

671 views

Original Research

Accepted on 24 Jun 2026

Design, build and test of a targeted synthetic protein strategy

in Synthetic Biology

Venkata V B Yallapragada
Arpit Shukla
Ciaran Devoy
Mark Tangney

Frontiers in Bioengineering and Biotechnology

214 views

Original Research

Accepted on 22 Jun 2026

A quality evaluation strategy for residual host cell proteins based on orthogonal analysis

in Synthetic Biology

Xinyue Hu
Ping Lyu
Dan Wang
Yi Li
Kezheng Xu
Feng Ling
Minhua Dou
Chenggang Liang
Jing Li

Frontiers in Bioengineering and Biotechnology

279 views

Original Research

Published on 17 Jun 2026

Engineering Lactococcus cremoris strains co-expressing two cellulase genes for growth on cellulose

in Synthetic Biology

Petra Štravs
Henri-Pierre Fierobe
Stéphanie Perret
Aleš Berlec

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1857763

733 views

Original Research

Published on 29 May 2026

Dissecting the disconnect between circuit activation and dominant adaptive evolution in cytoplasmic phage-assisted continuous evolution (PACE) of an EGFR nanobody

in Synthetic Biology

Jie-Ning Chuang
Jacob Purcell
Loki Sangalli
Joseph Rosenbluh
Gavin J. Knott
Simon Corrie
Gil Garnier

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1829373

1,260 views

Original Research

Published on 26 May 2026

Design and validation of an inducible and curable EvolvR system for directed evolution in Corynebacterium glutamicum

in Synthetic Biology

Paul M. Will
Vanessa L. Göttl
Jan Seeger
Volker F. Wendisch
Nadja A. Henke

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1827071

1,701 views

Original Research

Published on 08 May 2026

Gut-engineered Bacillus subtilis-mediated BAMBI delivery for the treatment of thioacetamide-induced liver fibrosis through mechanotransduction inhibition

in Synthetic Biology

Xiaochang Zhao
Yu Zhang
Xiangyu Chu
Wenqian Ma
Rongkai Zhan
Yan Wang
Haiyan Fang
Peng Guo
Ziye Wang
Xiaohan Chen

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1817519

1,142 views

Mini Review

Published on 29 Apr 2026

Engineering glowing plants: recent progress and future directions for application-oriented design

in Synthetic Biology

Guimeng Cui

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1819614

2,207 views

Original Research

Published on 26 Feb 2026

Codon deoptimization of multispecific biologics reduces mispairing during transient mammalian protein expression

in Synthetic Biology

Timothy Z. Chang
Weijun Ma
Jane Guo
Jiali Hu
Kalie Mix
Yi Tang
Karen Wong
Eva Bric-Furlong
Amanda Lennon
Brian Hall

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1783067

2,396 views

Original Research

Published on 20 Feb 2026

Construction and characterization of a nanopore derived from the transmembrane domain of a trimeric autotransporter adhesin

in Synthetic Biology

Jun Sasahara
Shogo Yoshimoto
Zugui Peng
Taehyun Hwang
Iori Kobayashi
Ryuji Kawano
Katsutoshi Hori

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1764864

1,349 views

Brief Research Report

Published on 17 Feb 2026

Prediction of non-intuitive metabolic targets with bayesian metabolic control analysis to improve 3-hydroxypropionic acid production in Aspergillus niger

in Synthetic Biology

Ziyu Dai
Jeremy D. Zucker
Yichao Han
Shant Mahserejian
Joseph Cottam
Nathalie Munoz
Yuqian Gao
Guoliang Yuan
Beth A. Hofstad
Jon K. Magnuson

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1754875

1,579 views

Brief Research Report

Published on 27 Jan 2026

AistSeq: An in-house easy-to-purify Tn5-based plasmid sequencing platform using a compact benchtop sequencer

in Synthetic Biology

Hayato Suzuki
Jutapat Romsuk
Akiyoshi Nakamura
Kosuke Moriwaki
Yoko Yamanishi
Shigeo S. Sugano

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1673510

1,964 views

Mini Review

Published on 15 Jan 2026

Beyond pigments and perfumes: engineering in the carotenoid and apocarotenoid spectrum, novel enzymes, and synthetic biology strategies

in Synthetic Biology

Baradwaj Ravi Gopal
Zhen Q. Wang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1716709

2,627 views
2 citations

Methods

Published on 09 Jan 2026

High-throughput optimization of antibody production in CHO cells by tuning heavy- and light-chain promoter strength

in Synthetic Biology

Marzia Rahimi
Anna Christina Adams
Lise M. Grav
Lars K. Nielsen
Jesús Lavado-García

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1747473

5,494 views

Opinion

Published on 07 Jan 2026

From detection to remediation: the potential of phosphomelanin in sustainable environmental solutions

in Synthetic Biology

Chang-ye Hui

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1724585

1,471 views

Editorial

Published on 06 Jan 2026

Editorial: Synthetic biology and metabolomics: novel insight in oncology research

in Synthetic Biology

Ruby Dhar
Karthikeyan Pethusamy
Manash K. Paul
Subhradip Karmakar

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1768397

1,335 views

806 articles

articles

Efficient, complete biosynthesis of isoflavonoid calycosin-7-glucoside by metabolically engineered yeast cell factories

Editorial: Advancements in microbial engineering for natural product synthesis

Beyond glucose: wearable and implantable biosensors for continuous monitoring of metabolic, hormonal, and inflammatory biomarkers in personalized cardiometabolic care

Synthetic biology and genome engineering in support of human, agricultural, and environmental security

Beyond Enzyme Engineering: Ordered enzyme immobilization drives enhanced productivity in vitro

Chemical organizations as a conceptual tool: from synthetic biology to interdisciplinary systems and back

Bioinks in systems biology: integrating biomaterial design with cellular network modelling for predictive biofabrication

Interaction between crgA and wc-1b in carotenoid synthesis in Blakeslea trispora

Microbial conversion of biodiesel waste for carotenoid production

Design, build and test of a targeted synthetic protein strategy

A quality evaluation strategy for residual host cell proteins based on orthogonal analysis

Engineering Lactococcus cremoris strains co-expressing two cellulase genes for growth on cellulose

Dissecting the disconnect between circuit activation and dominant adaptive evolution in cytoplasmic phage-assisted continuous evolution (PACE) of an EGFR nanobody

Design and validation of an inducible and curable EvolvR system for directed evolution in Corynebacterium glutamicum

Gut-engineered Bacillus subtilis-mediated BAMBI delivery for the treatment of thioacetamide-induced liver fibrosis through mechanotransduction inhibition

Engineering glowing plants: recent progress and future directions for application-oriented design

Codon deoptimization of multispecific biologics reduces mispairing during transient mammalian protein expression

Construction and characterization of a nanopore derived from the transmembrane domain of a trimeric autotransporter adhesin

Prediction of non-intuitive metabolic targets with bayesian metabolic control analysis to improve 3-hydroxypropionic acid production in Aspergillus niger

AistSeq: An in-house easy-to-purify Tn5-based plasmid sequencing platform using a compact benchtop sequencer

Beyond pigments and perfumes: engineering in the carotenoid and apocarotenoid spectrum, novel enzymes, and synthetic biology strategies

High-throughput optimization of antibody production in CHO cells by tuning heavy- and light-chain promoter strength

From detection to remediation: the potential of phosphomelanin in sustainable environmental solutions

Editorial: Synthetic biology and metabolomics: novel insight in oncology research