Frontiers in Cardiovascular Medicine | Cardiovascular Biologics and Regenerative Medicine

Original Research

Published on 14 Oct 2025

Pregnancy hormones increase cardiac capillary density via the PGC-1α/ERRα/VEGF pathway in cardiomyocytes

in Cardiovascular Biologics and Regenerative Medicine

Michael Hesse
Daniel Korzus
Kristina Thaben
Nicole Wagner
Süleyman Ergün
Zoltan Arany
Bernd K. Fleischmann

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1688831

740 views

Mini Review

Published on 29 Sep 2025

Cardiac disease mechanobiology: advances using hiPSC-CMs

in Cardiovascular Biologics and Regenerative Medicine

Georgina Aluoch Stephanie
Alison Schroer Vander Roest

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1642931

1,443 views

Original Research

Published on 29 Aug 2025

Transfer of remote ischemic preconditioning plasma from heart transplant patients into isolated perfused rat hearts prior ischemia/reperfusion injury—a translational study of cardioprotection

in Cardiovascular Biologics and Regenerative Medicine

Gizem Bingöl
Steve Jesurasa
Martin Stroethoff
Julian David Jagdfeld
Leila Sophie Henning
Sebastian Roth
Giovanna Lurati Buse
René M'Pembele
Annika Raupach

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1631222

1,407 views

Review

Published on 21 Aug 2025

tRNA-derived small RNAs (tsRNAs) in cardiovascular diseases: biogenesis, functions, and therapeutic targets

in Cardiovascular Biologics and Regenerative Medicine

Chunfeng Xie
Sihong Chen
Chengyuan Wang
Wei Si
Zidan Wang
Qi Luo
Chan Qi

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1622248

2,250 views

Brief Research Report

Published on 15 Aug 2025

Transcription factor ETV1 promotes angiogenesis after myocardial infarction via activation of the VEGFA/VEGFR2/eNOS pathway

in Cardiovascular Biologics and Regenerative Medicine

Jinyu Wang
Chunxia Li
Feng Li
Sen Fang
Yuan Chen

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1633438

1,599 views

Original Research

Published on 13 Aug 2025

Single-cell transcriptomic analysis of the human vascular atlas provides new insights into vasorelaxation redundancy and heterogeneity

in Cardiovascular Biologics and Regenerative Medicine

Elisa Avolio
Sarah F. Pearce
David Wambeke
Paolo Madeddu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1634645

1,953 views

Review

Published on 24 Jul 2025

Unveiling the intricacies of cardiac valve pathophysiology

in Cardiovascular Biologics and Regenerative Medicine

Johannes H. Jedrzejczyk
Oline Hjertensgaard
Victor G. Puelles
J. Michael Hasenkam

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1570271

1,628 views

Review

Published on 15 Jul 2025

Post-translational modifications orchestrate mTOR-driven cell death in cardiovascular disease

in Cardiovascular Biologics and Regenerative Medicine

Jiawei Guo
Yiting Wu
Zhengdong Wan
Zhaoshan Zhang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1620669

3,314 views
1 citation

Brief Research Report

Published on 02 Jul 2025

TNIK-driven regulation of ERK5 transcriptional activity in endothelial cells

in Cardiovascular Biologics and Regenerative Medicine

Venkata Subrahmanya Kumar Samanthapudi
Sivareddy Kotla
Nhat-Tu Le

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1526676

2,551 views

Original Research

Published on 30 Jun 2025

Shifting landscapes: dynamic changes from pro- to anti-inflammatory leukocyte phenotype in myocardial ischemia/reperfusion injury

in Cardiovascular Biologics and Regenerative Medicine

Pia Kröning
Maximilian Mauler
Nancy Schanze
Katharina Naber
Daniela Stallmann
Daniel Duerschmied
Dirk Westermann
Nadine Gauchel

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1596538

1,556 views

Systematic Review

Published on 25 Jun 2025

Tissue response and clinical outcomes after cardiovascular use of porcine small intestinal small intestinal submucosal extracellular matrix: a systematic review

in Cardiovascular Biologics and Regenerative Medicine

Villads Juul Bruun
Line Lyngbak Jensen
J. Michael Hasenkam
Johannes H. Jedrzejczyk

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1532157

1,300 views

Original Research

Published on 24 Jun 2025

Directing cell delivery to murine atherosclerotic aortic lesions via targeting inflamed circulatory interface using nanocarriers

in Cardiovascular Biologics and Regenerative Medicine

Carlos Theodore Huerta
Leiming Zhang
Yulexi Y. Ortiz
Yan Li
Elnaz Zeynaloo
Emre Dikici
Teruna J. Siahaan
Sapna K. Deo
Sylvia Daunert
Zhao-Jun Liu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1517320

1,271 views

Original Research

Published on 03 Jun 2025

An immunostaining-based approach for assessing myocardial viability in the infarcted mouse hearts

in Cardiovascular Biologics and Regenerative Medicine

Weili Ouyang
Xueqing Liu
Zheheng Ding
Yanan Ji
Jianfeng Zhao
Hongtao Zhu
Weidong Wu
Zhaoping Ding

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1598314

1,849 views

Review

Published on 20 May 2025

Cardiac organoids: a new tool for disease modeling and drug screening applications

in Cardiovascular Biologics and Regenerative Medicine

Ahmed Yaqinuddin
Abdullah Jabri
Abdulaziz Mhannayeh
Bader Taftafa
Mohamed Alsharif
Tasnim Abbad
Jibran Khan
Abdulrahman Elsalti
Raja Chinnappan
Eman A. Alshehri

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1537730

4,976 views
2 citations

Review

Published on 01 May 2025

The role of deubiquitinases in cardiovascular diseases: mechanisms and therapeutic implications

in Cardiovascular Biologics and Regenerative Medicine

Xiangyu Fei
Chao Song
Jian Cui
Yuqing Li
Xiaoyong Lei
Huifang Tang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1582049

4,156 views
1 citation

Review

Published on 28 Apr 2025

Cell cycle arrest of cardiomyocytes in the context of cardiac regeneration

in Cardiovascular Biologics and Regenerative Medicine

Qingling Xu
Xinhui Chen
Chunyige Zhao
Ying Liu
Jianxun Wang
Xiang Ao
Wei Ding

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1538546

2,753 views