Frontiers in Cardiovascular Medicine | Cardiovascular Biologics and Regenerative Medicine

Original Research

Published on 23 Apr 2026

A new approach methodology for studying intrinsic ventricular arrhythmias in Fabry disease

in Cardiovascular Biologics and Regenerative Medicine

Andre Monteiro da Rocha
Liming Shu
Prakaimuk Saraithong
Erinn Laimon-Thomson
Kalai Muthukumarasamy
Todd Herron
James A. Shayman

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1769383

684 views

Original Research

Published on 10 Apr 2026

Bioenergetic and metabolic aberrations in induced pluripotent stem cell-derived cardiomyocytes generated from a patient with Wolff-Parkinson-White syndrome caused a PRKAG2 mutation

in Cardiovascular Biologics and Regenerative Medicine

Polina Baskin
Ifat Abramovich
Helena Milman
Ronen Ben Jehuda
Bella Agranovich
Mor Davidor
Valerie Buffard
Todd Herron
Ferhaan Ahmad
Michael Arad

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1719965

503 views

Review

Published on 25 Mar 2026

Microtubule dynamics and post-translational modifications in cardiovascular diseases: mechanisms and therapeutic implications

in Cardiovascular Biologics and Regenerative Medicine

Lin Cui
Lulu Guo
Lufei Yang
Yuehao Zhang
Chunfen Ma

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1792687

476 views

Editorial

Published on 11 Mar 2026

Editorial: Natural antioxidants and cardiovascular diseases: a pathway to prevention

in Cardiovascular Biologics and Regenerative Medicine

Roberta Giordo
Anna Maria Posadino

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1813976

386 views

Review

Published on 16 Jan 2026

The mechanism of secreted frizzled-related protein 1 in alleviating cardiomyocyte injury and heart failure

in Cardiovascular Biologics and Regenerative Medicine

Yu He
Tianrun Liu
Li Chen
Zimeng Ge
Xuefeng Chang
Deli Zou

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1676224

1,151 views

Case Report

Published on 08 Dec 2025

Case Report: Single-cell RNA sequencing reveals cellular and molecular mechanisms in newborn cardiac hemangioma formation

in Cardiovascular Biologics and Regenerative Medicine

Tiange Li
Qi An
Shuhua Luo
Yifei Li

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1682677

1,631 views

Review

Published on 26 Nov 2025

The role of the PD-1/PD-L1 immune checkpoint pathway in myocardial infarction: a review from pathophysiological mechanisms to therapeutic strategies

in Cardiovascular Biologics and Regenerative Medicine

Zilong Luo
Han Zhang
Junjie Zong
Jun Hu
Pinyan Huang
Yuqing Niu
Cheng Zhou
Song Wang
Dan Zhang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1691863

1,975 views
2 citations

Original Research

Published on 18 Nov 2025

Effects of anesthetic agents on the evaluation of systolic and diastolic function in mice

in Cardiovascular Biologics and Regenerative Medicine

Dzmitry Matsiukevich
David M. Ornitz
Attila Kovacs

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1707937

1,687 views

Original Research

Published on 13 Nov 2025

Screening and characterization of natural extracts as dual-functional regulators for cardiomyocyte regeneration and cardiac repair

in Cardiovascular Biologics and Regenerative Medicine

Jianfeng Liu
Chunyan Kuang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1701482

1,245 views

Original Research

Published on 14 Oct 2025

Pregnancy hormones increase cardiac capillary density via the PGC-1α/ERRα/VEGF pathway in cardiomyocytes

in Cardiovascular Biologics and Regenerative Medicine

Michael Hesse
Daniel Korzus
Kristina Thaben
Nicole Wagner
Süleyman Ergün
Zoltan Arany
Bernd K. Fleischmann

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1688831

2,170 views

Mini Review

Published on 29 Sep 2025

Cardiac disease mechanobiology: advances using hiPSC-CMs

in Cardiovascular Biologics and Regenerative Medicine

Georgina Aluoch Stephanie
Alison Schroer Vander Roest

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1642931

3,788 views
3 citations

Original Research

Published on 29 Aug 2025

Transfer of remote ischemic preconditioning plasma from heart transplant patients into isolated perfused rat hearts prior ischemia/reperfusion injury—a translational study of cardioprotection

in Cardiovascular Biologics and Regenerative Medicine

Gizem Bingöl
Steve Jesurasa
Martin Stroethoff
Julian David Jagdfeld
Leila Sophie Henning
Sebastian Roth
Giovanna Lurati Buse
René M'Pembele
Annika Raupach

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1631222

2,327 views

Review

Published on 21 Aug 2025

tRNA-derived small RNAs (tsRNAs) in cardiovascular diseases: biogenesis, functions, and therapeutic targets

in Cardiovascular Biologics and Regenerative Medicine

Chunfeng Xie
Sihong Chen
Chengyuan Wang
Wei Si
Zidan Wang
Qi Luo
Chan Qi

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1622248

4,092 views
4 citations

Brief Research Report

Published on 15 Aug 2025

Transcription factor ETV1 promotes angiogenesis after myocardial infarction via activation of the VEGFA/VEGFR2/eNOS pathway

in Cardiovascular Biologics and Regenerative Medicine

Jinyu Wang
Chunxia Li
Feng Li
Sen Fang
Yuan Chen

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1633438

2,664 views

Original Research

Published on 13 Aug 2025

Single-cell transcriptomic analysis of the human vascular atlas provides new insights into vasorelaxation redundancy and heterogeneity

in Cardiovascular Biologics and Regenerative Medicine

Elisa Avolio
Sarah F. Pearce
David Wambeke
Paolo Madeddu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1634645

3,824 views
2 citations

Review

Published on 24 Jul 2025

Unveiling the intricacies of cardiac valve pathophysiology

in Cardiovascular Biologics and Regenerative Medicine

Johannes H. Jedrzejczyk
Oline Hjertensgaard
Victor G. Puelles
J. Michael Hasenkam

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1570271

3,487 views

Review

Published on 15 Jul 2025

Post-translational modifications orchestrate mTOR-driven cell death in cardiovascular disease

in Cardiovascular Biologics and Regenerative Medicine

Jiawei Guo
Yiting Wu
Zhengdong Wan
Zhaoshan Zhang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1620669

5,575 views
1 citation

Brief Research Report

Published on 02 Jul 2025

TNIK-driven regulation of ERK5 transcriptional activity in endothelial cells

in Cardiovascular Biologics and Regenerative Medicine

Venkata Subrahmanya Kumar Samanthapudi
Sivareddy Kotla
Nhat-Tu Le

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1526676

4,276 views
2 citations

Original Research

Published on 30 Jun 2025

Shifting landscapes: dynamic changes from pro- to anti-inflammatory leukocyte phenotype in myocardial ischemia/reperfusion injury

in Cardiovascular Biologics and Regenerative Medicine

Pia Kröning
Maximilian Mauler
Nancy Schanze
Katharina Naber
Daniela Stallmann
Daniel Duerschmied
Dirk Westermann
Nadine Gauchel

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1596538

2,600 views

Systematic Review

Published on 25 Jun 2025

Tissue response and clinical outcomes after cardiovascular use of porcine small intestinal small intestinal submucosal extracellular matrix: a systematic review

in Cardiovascular Biologics and Regenerative Medicine

Villads Juul Bruun
Line Lyngbak Jensen
J. Michael Hasenkam
Johannes H. Jedrzejczyk

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1532157

2,188 views
3 citations

Original Research

Published on 24 Jun 2025

Directing cell delivery to murine atherosclerotic aortic lesions via targeting inflamed circulatory interface using nanocarriers

in Cardiovascular Biologics and Regenerative Medicine

Carlos Theodore Huerta
Leiming Zhang
Yulexi Y. Ortiz
Yan Li
Elnaz Zeynaloo
Emre Dikici
Teruna J. Siahaan
Sapna K. Deo
Sylvia Daunert
Zhao-Jun Liu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1517320

2,060 views
2 citations

Original Research

Published on 03 Jun 2025

An immunostaining-based approach for assessing myocardial viability in the infarcted mouse hearts

in Cardiovascular Biologics and Regenerative Medicine

Weili Ouyang
Xueqing Liu
Zheheng Ding
Yanan Ji
Jianfeng Zhao
Hongtao Zhu
Weidong Wu
Zhaoping Ding

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1598314

3,491 views
1 citation

Review

Published on 20 May 2025

Cardiac organoids: a new tool for disease modeling and drug screening applications

in Cardiovascular Biologics and Regenerative Medicine

Ahmed Yaqinuddin
Abdullah Jabri
Abdulaziz Mhannayeh
Bader Taftafa
Mohamed Alsharif
Tasnim Abbad
Jibran Khan
Abdulrahman Elsalti
Raja Chinnappan
Eman A. Alshehri

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1537730

11,102 views
9 citations

Review

Published on 01 May 2025

The role of deubiquitinases in cardiovascular diseases: mechanisms and therapeutic implications

in Cardiovascular Biologics and Regenerative Medicine

Xiangyu Fei
Chao Song
Jian Cui
Yuqing Li
Xiaoyong Lei
Huifang Tang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1582049

6,247 views
3 citations

355 articles

articles

A new approach methodology for studying intrinsic ventricular arrhythmias in Fabry disease

Bioenergetic and metabolic aberrations in induced pluripotent stem cell-derived cardiomyocytes generated from a patient with Wolff-Parkinson-White syndrome caused a PRKAG2 mutation

Microtubule dynamics and post-translational modifications in cardiovascular diseases: mechanisms and therapeutic implications

Editorial: Natural antioxidants and cardiovascular diseases: a pathway to prevention

The mechanism of secreted frizzled-related protein 1 in alleviating cardiomyocyte injury and heart failure

Case Report: Single-cell RNA sequencing reveals cellular and molecular mechanisms in newborn cardiac hemangioma formation

The role of the PD-1/PD-L1 immune checkpoint pathway in myocardial infarction: a review from pathophysiological mechanisms to therapeutic strategies

Effects of anesthetic agents on the evaluation of systolic and diastolic function in mice

Screening and characterization of natural extracts as dual-functional regulators for cardiomyocyte regeneration and cardiac repair

Pregnancy hormones increase cardiac capillary density via the PGC-1α/ERRα/VEGF pathway in cardiomyocytes

Cardiac disease mechanobiology: advances using hiPSC-CMs

Transfer of remote ischemic preconditioning plasma from heart transplant patients into isolated perfused rat hearts prior ischemia/reperfusion injury—a translational study of cardioprotection

tRNA-derived small RNAs (tsRNAs) in cardiovascular diseases: biogenesis, functions, and therapeutic targets

Transcription factor ETV1 promotes angiogenesis after myocardial infarction via activation of the VEGFA/VEGFR2/eNOS pathway

Single-cell transcriptomic analysis of the human vascular atlas provides new insights into vasorelaxation redundancy and heterogeneity

Unveiling the intricacies of cardiac valve pathophysiology

Post-translational modifications orchestrate mTOR-driven cell death in cardiovascular disease

TNIK-driven regulation of ERK5 transcriptional activity in endothelial cells

Shifting landscapes: dynamic changes from pro- to anti-inflammatory leukocyte phenotype in myocardial ischemia/reperfusion injury

Tissue response and clinical outcomes after cardiovascular use of porcine small intestinal small intestinal submucosal extracellular matrix: a systematic review

Directing cell delivery to murine atherosclerotic aortic lesions via targeting inflamed circulatory interface using nanocarriers

An immunostaining-based approach for assessing myocardial viability in the infarcted mouse hearts

Cardiac organoids: a new tool for disease modeling and drug screening applications

The role of deubiquitinases in cardiovascular diseases: mechanisms and therapeutic implications