Frontiers in Cardiovascular Medicine | Cardiovascular Biologics and Regenerative Medicine

Original Research

Accepted on 15 Jul 2025

Single-cell transcriptomic analysis of the human vascular atlas provides new insights into vasorelaxation redundancy and heterogeneity

in Cardiovascular Biologics and Regenerative Medicine

Elisa Avolio
Sarah Pearce
Dave Wambeke
Paolo Madeddu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1634645

146 views

Review

Published on 15 Jul 2025

Post-translational modifications orchestrate mTOR-driven cell death in cardiovascular disease

in Cardiovascular Biologics and Regenerative Medicine

Jiawei Guo
Yiting Wu
Zhengdong Wan
Zhaoshan Zhang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1620669

426 views

Review

Accepted on 08 Jul 2025

Unveiling the Intricacies of Cardiac Valve Pathophysiology

in Cardiovascular Biologics and Regenerative Medicine

Johannes Jedrzejczyk
Oline Hjertensgaard
Victor Puelles
J. Michael Hasenkam

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1570271

156 views

Brief Research Report

Published on 02 Jul 2025

TNIK-driven regulation of ERK5 transcriptional activity in endothelial cells

in Cardiovascular Biologics and Regenerative Medicine

Venkata Subrahmanya Kumar Samanthapudi
Sivareddy Kotla
Nhat-Tu Le

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1526676

866 views

Original Research

Published on 30 Jun 2025

Shifting landscapes: dynamic changes from pro- to anti-inflammatory leukocyte phenotype in myocardial ischemia/reperfusion injury

in Cardiovascular Biologics and Regenerative Medicine

Pia Kröning
Maximilian Mauler
Nancy Schanze
Katharina Naber
Daniela Stallmann
Daniel Duerschmied
Dirk Westermann
Nadine Gauchel

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1596538

766 views

Systematic Review

Published on 25 Jun 2025

Tissue response and clinical outcomes after cardiovascular use of porcine small intestinal small intestinal submucosal extracellular matrix: a systematic review

in Cardiovascular Biologics and Regenerative Medicine

Villads Juul Bruun
Line Lyngbak Jensen
J. Michael Hasenkam
Johannes H. Jedrzejczyk

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1532157

744 views

Original Research

Published on 24 Jun 2025

Directing cell delivery to murine atherosclerotic aortic lesions via targeting inflamed circulatory interface using nanocarriers

in Cardiovascular Biologics and Regenerative Medicine

Carlos Theodore Huerta
Leiming Zhang
Yulexi Y. Ortiz
Yan Li
Elnaz Zeynaloo
Emre Dikici
Teruna J. Siahaan
Sapna K. Deo
Sylvia Daunert
Zhao-Jun Liu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1517320

692 views

Original Research

Published on 03 Jun 2025

An immunostaining-based approach for assessing myocardial viability in the infarcted mouse hearts

in Cardiovascular Biologics and Regenerative Medicine

Weili Ouyang
Xueqing Liu
Zheheng Ding
Yanan Ji
Jianfeng Zhao
Hongtao Zhu
Weidong Wu
Zhaoping Ding

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1598314

953 views

Review

Published on 20 May 2025

Cardiac organoids: a new tool for disease modeling and drug screening applications

in Cardiovascular Biologics and Regenerative Medicine

Ahmed Yaqinuddin
Abdullah Jabri
Abdulaziz Mhannayeh
Bader Taftafa
Mohamed Alsharif
Tasnim Abbad
Jibran Khan
Abdulrahman Elsalti
Raja Chinnappan
Eman A. Alshehri

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1537730

2,305 views

Review

Published on 01 May 2025

The role of deubiquitinases in cardiovascular diseases: mechanisms and therapeutic implications

in Cardiovascular Biologics and Regenerative Medicine

Xiangyu Fei
Chao Song
Jian Cui
Yuqing Li
Xiaoyong Lei
Huifang Tang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1582049

2,682 views

Review

Published on 28 Apr 2025

Cell cycle arrest of cardiomyocytes in the context of cardiac regeneration

in Cardiovascular Biologics and Regenerative Medicine

Qingling Xu
Xinhui Chen
Chunyige Zhao
Ying Liu
Jianxun Wang
Xiang Ao
Wei Ding

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1538546

1,667 views

Review

Published on 11 Apr 2025

Macrophages and cardiac lesion in zebrafish: what can single-cell RNA sequencing reveal?

in Cardiovascular Biologics and Regenerative Medicine

Rebeca Bosso dos Santos Luz
André Guilherme Portela Paula
Andressa Pacheco Czaikovski
Bruno Sime Ferreira Nunes
Jordana Dinora De Lima
Lais Cavalieri Paredes
Thais Sibioni Berti Bastos
Rebecca Richardson
Tarcio Teodoro Braga

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1570582

2,047 views

Hypothesis and Theory

Published on 01 Apr 2025

Elucidating the preventive and therapeutic effects of cardiac telocytes paracrine microRNAs on ischemic heart disease

in Cardiovascular Biologics and Regenerative Medicine

Hugang Jiang
Yan Tang
Ai Liu
Chunzhen Ren
Wenyan Lin
Kai Liu
Xinke Zhao
Yingdong Li

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1540051

1,188 views

Review

Published on 07 Feb 2025

Regenerative therapies for myocardial infarction: exploring the critical role of energy metabolism in achieving cardiac repair

in Cardiovascular Biologics and Regenerative Medicine

Jiahao Ren
Xinzhe Chen
Tao Wang
Cuiyun Liu
Kun Wang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1533105

1,665 views

Original Research

Published on 06 Jan 2025

Effects of dapagliflozin on heart rate variability, cardiac function, and short-term prognosis in early-onset post-myocardial infarction heart failure

in Cardiovascular Biologics and Regenerative Medicine

Le Zhou
Mingyuan Niu
Wei Chen
Qian Hu
Yi Chen
Xiaohong Geng
Jiani Gu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1490316

1,657 views

Original Research

Published on 10 Oct 2024

Mapping the landscape of PSC-CM research through bibliometric analysis

in Cardiovascular Biologics and Regenerative Medicine

Jun Li
Shangting Han
Fengxu Yu
Tao Li
Bin Liao
Feng Liu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1435874

4,097 views