Frontiers in Cell and Developmental Biology

Original Research

Published on 18 Dec 2025

Cecal growth factors promote enteric neurosphere formation and hindgut colonization in the avian model

in Embryonic Development

Ádám Soós
Emőke Szőcs
Viktória Halasy
Zsanna Gecse
Fruzsina Mógor
Csenge Jurenka
Katalin Kocsis
Jitka Mucksová
Jiří Hejnar
Nándor Nagy

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1681844

234 views

Methods

Published on 18 Dec 2025

Optimized protocols for generating half-sized embryos from separated first two blastomeres in green sea urchin and Xenopus laevis

in Embryonic Development

Eugeny E. Orlov
Polina S. Timoshina
Elena A. Parshina
Fedor M. Eroshkin
Maria A. Bannikova
Andrey G. Zaraisky

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1730288

134 views

Original Research

Published on 18 Dec 2025

Disruption of Swell1/VRAC function impairs initial hemodynamics and activates compensatory leukotriene signaling in zebrafish circulation development

in Embryonic Development

Yen-Tzu Tseng
Chia-Teng Chang
Wei-Chun HuangFu
I.-Hsuan Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1719544

420 views

Original Research

Published on 16 Dec 2025

Multi-omics analysis reveals a protective role of endogenous proline in sheep oocyte vitrification and its therapeutic application

in Embryonic Development

Airixiati Dilixiati
Xi Zhao
Aikebaier Aihemaiti
Weijian Li
Chen Fan
Guodong Zhao
Abulizi Wusiman
Xuguang Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1714529

265 views

Original Research

Published on 08 Dec 2025

Maternal provisioning and zygotic activation: transcriptomic dynamics of early atlantic halibut (Hippoglossus hippoglossus) embryogenesis

in Embryonic Development

Nils Niepagen
Francesca Bertolini
Leif Berg
Jonna Tomkiewicz
Elin Kjørsvik

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1723170

530 views

Original Research

Accepted on 05 Dec 2025

Developmental and reproductive toxicity assessment of sporoderm-removed Ganoderma lucidum spores

in Embryonic Development

Junxiu Liu
Yisheng Song
Chuanhuai Chen
Jing Liu
Siming Zhang
Fang Liu
Ruiyu Tian
Jinjin Shao
Lili Zhang
Tingli Bian

Frontiers in Cell and Developmental Biology

279 views

Original Research

Accepted on 05 Dec 2025

Kv2.1 Negatively Regulates Reissner Fiber Development

in Embryonic Development

R. Rosa Amini
Ruchi P. Jain
Justyna Jędrychowska
Vladimir Korzh

Frontiers in Cell and Developmental Biology

197 views

Original Research

Published on 03 Dec 2025

Long-chain fatty acid β-oxidation regulates embryonic development by H3K18 acetylation in mice

in Embryonic Development

Kefan Zheng
Hongdi Cui
Ziheng Tang
Entong Song
Qingran Kong
Jiaming Zhang
Hao Li
Qi Zhao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1683028

553 views

Original Research

Published on 28 Nov 2025

Tissue block-resolved developmental transcriptomic atlas of human fetal brainstem reveals gene modules with implications for neurological disorders

in Embryonic Development

Chengxin Liu
Wenjuan Zhou
Xin Xing
Jiachen Chen
Chenxi Sun
Shizhou Liu
Yunxia Lou
Jianfen Jiao
Haoling Cao
Baoxia Cui

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1674967

579 views

Original Research

Published on 27 Nov 2025

Hypertensive disorders of pregnancy increase neonatal cerebral regional tissue oxygen saturation in the early postnatal period: partial mediation by preterm birth

in Embryonic Development

Yao Zhang
Tong Yang
Dengjun Liu
Jiaxi Wu
Yanxia Mao
Dapeng Chen
Jun Tang
Yi Yang
Tao Xiong

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1682675

405 views

Original Research

Accepted on 24 Nov 2025

Metabolic patterns predispose human pluripotent stem cells to spatial organization of cell fate

in Embryonic Development

Chunhao Deng
Zhaoying Zhang
Xia Xiao
Carlos Godoy-Parejo
Faxiang Xu
Chengcheng Song
Huanyi Lin
Qinru Li
Shicai Fang
Weiwei Liu

Frontiers in Cell and Developmental Biology

155 views

Review

Published on 24 Nov 2025

Cis-regulatory elements operating in the trophoblast

in Embryonic Development

Terezia Vcelkova
Paulina A. Latos

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1661952

839 views

Review

Published on 17 Nov 2025

Linking the Warburg effect to endometrial receptivity: metabolic parallels in embryo implantation

in Embryonic Development

Xiaoyang Zhang
Qingwen Zhu
Weiduo Nie
Xiaoxue Yan
Zhihua Yuan
Leiyu Tian

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1683790

1,333 views

Brief Research Report

Published on 13 Nov 2025

Tissue-resident macrophages co-develop with myocardial tissue in human induced pluripotent stem cell-derived organoids

in Embryonic Development

Anna Frederike Rockel
Tobias Brunnbauer
Nicole Wagner
Brenda Gerull
Süleyman Ergün
Philipp Wörsdörfer

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1629988

1,648 views

Original Research

Published on 07 Nov 2025

MitoLandscape, a semi-automated pipeline for subcellular localization and quantification of mitochondria

in Embryonic Development

Enrico Negri
Virginia Fernández
Víctor Borrell

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1668779

1,020 views

Original Research

Published on 29 Oct 2025

Early increased cell proliferation compensates subsequent hypoplasia of the ossicle

in Embryonic Development

Katsushige Kawasaki
Maiko Kawasaki
Finsa Tisna Sari
Vanessa Utama
Alex Kesuma
Makoto Fukushima
Naoaki Saito
Daisuke Suda
Takehisa Kudo
Akira Fujita

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1627730

1,242 views

Original Research

Published on 17 Oct 2025

Screening for novel factors involved in mouse early embryonic development using inhibitor libraries

in Embryonic Development

Hirofumi Nishizono
Masaki Kato

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1643551

2,499 views

Original Research

Published on 09 Oct 2025

Effects of hormone-primed oviduct epithelial cell co-culture system on swine SCNT embryo development

in Embryonic Development

Zhong-Ping Chen
Jian Wang
Chang-Di Bian
Dong-Yue Wang
De-Hui Feng
Ming-Yi Wei
Da-Wei Yu
Wei-Jun Sun
Lin-Lin Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1692877

1,631 views

Review

Published on 07 Oct 2025

Placental biomarkers for the prediction of neurodevelopmental disorders

in Embryonic Development

Payal Patel
Joy Ku
Ike Uzoaru
Jeffery A. Goldstein

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1663960

1,701 views
1 citation

Original Research

Published on 30 Sep 2025

Differential regulation of gene co-expression modules in muscles and liver of preterm newborns

in Embryonic Development

Petra Janovska
Tatyana Kobets
Lenka Steiner Mrazova
Michaela Svobodova
Marketa Tesarova
Pavel Kopecky
Petr Zouhar
Martin Rossmeisl
Viktor Stranecky
Stanislav Kmoch

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1645959

2,253 views
1 citation

Original Research

Published on 22 Sep 2025

Excessive progesterone impairs mouse decidualization via the Kyn-AhR pathway

in Embryonic Development

Hui-Na Luo
Hong-Yuan Yang
Zai-Mei Wang
Jia-Mei Luo
Tong-Tong Zhang
Zeng-Ming Yang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1622998

1,935 views

Review

Published on 19 Sep 2025

The role and regulatory mechanisms of the TCA cycle in early embryonic development

in Embryonic Development

Yipan Lai
Xiurong Gao
Liwen Zhao
Jin Liu
Chao Gao
Qingfu Yan
Yangneng Zeng
Zibing Liao
Jianing Zhong

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1662431

3,139 views
1 citation

Review

Published on 18 Sep 2025

Decoding congenital heart disease: a multi-omic framework for cardiac lineage and regulatory dysfunction

in Embryonic Development

Huasheng Lv
Fengyu Sun
You Chen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1659884

2,957 views

Mini Review

Published on 10 Sep 2025

Three-dimensional microarchitecture of the human placental villous tree in health and disease

in Embryonic Development

Nirav Barapatre
Hans-Georg Frank

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1639740

2,092 views

117 articles

articles

Cecal growth factors promote enteric neurosphere formation and hindgut colonization in the avian model

Optimized protocols for generating half-sized embryos from separated first two blastomeres in green sea urchin and Xenopus laevis

Disruption of Swell1/VRAC function impairs initial hemodynamics and activates compensatory leukotriene signaling in zebrafish circulation development

Multi-omics analysis reveals a protective role of endogenous proline in sheep oocyte vitrification and its therapeutic application

Maternal provisioning and zygotic activation: transcriptomic dynamics of early atlantic halibut (Hippoglossus hippoglossus) embryogenesis

Developmental and reproductive toxicity assessment of sporoderm-removed Ganoderma lucidum spores

Kv2.1 Negatively Regulates Reissner Fiber Development

Long-chain fatty acid β-oxidation regulates embryonic development by H3K18 acetylation in mice

Tissue block-resolved developmental transcriptomic atlas of human fetal brainstem reveals gene modules with implications for neurological disorders

Hypertensive disorders of pregnancy increase neonatal cerebral regional tissue oxygen saturation in the early postnatal period: partial mediation by preterm birth

Metabolic patterns predispose human pluripotent stem cells to spatial organization of cell fate

Cis-regulatory elements operating in the trophoblast

Linking the Warburg effect to endometrial receptivity: metabolic parallels in embryo implantation

Tissue-resident macrophages co-develop with myocardial tissue in human induced pluripotent stem cell-derived organoids

MitoLandscape, a semi-automated pipeline for subcellular localization and quantification of mitochondria

Early increased cell proliferation compensates subsequent hypoplasia of the ossicle

Screening for novel factors involved in mouse early embryonic development using inhibitor libraries

Effects of hormone-primed oviduct epithelial cell co-culture system on swine SCNT embryo development

Placental biomarkers for the prediction of neurodevelopmental disorders

Differential regulation of gene co-expression modules in muscles and liver of preterm newborns

Excessive progesterone impairs mouse decidualization via the Kyn-AhR pathway

The role and regulatory mechanisms of the TCA cycle in early embryonic development

Decoding congenital heart disease: a multi-omic framework for cardiac lineage and regulatory dysfunction

Three-dimensional microarchitecture of the human placental villous tree in health and disease