Frontiers in Cell and Developmental Biology | Epigenomics and Epigenetics

Original Research

Published on 05 Dec 2025

Effects of selenium-mediated RUNX2 overexpression and its transcriptome alterations on Chondrocyte injury in Kashin Beck disease

in Epigenomics and Epigenetics

Di Zhang
Qiang Li
Xiaoli Yang
Yongmin Xiong
Shiquan Sun

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1687954

436 views

Review

Published on 01 Dec 2025

Role of histone post-translational modifications in atherosclerosis and the therapeutic potential of targeting epigenetic modifiers

in Epigenomics and Epigenetics

Lili Wu
Wei Li
Wei Ye

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1705966

674 views

Mini Review

Published on 01 Dec 2025

RBM15-mediated m6A modification in cancer progression and tumor immunity: molecular mechanisms and therapeutic potential

in Epigenomics and Epigenetics

Chunhong Li
Xiulin Jiang
Yixiao Yuan
Qiang Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1713615

358 views

Original Research

Published on 27 Nov 2025

DANCR promotes septic cardiomyopathy by enhancing macrophage glycolytic reprogramming via the IGF2BP2/HK2 axis

in Epigenomics and Epigenetics

Chunhui Ma
Shaoyu Liu
Yu Zhao
Hong Liu
Xuguang Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1628915

418 views

Review

Published on 18 Nov 2025

Research advances in m6A methylation and sepsis

in Epigenomics and Epigenetics

Lifan Zhang
Wenjuan Chen
Yafeng Liu
Shujun Zhang
Bingyou Yin
Kaijie Liu
Xinyu Gu
Xinjun Hu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1682283

666 views

Review

Published on 14 Nov 2025

Super enhancers as key drivers of gene regulatory networks in normal and malignant hematopoiesis

in Epigenomics and Epigenetics

Ying Cheng
Guangxin Pei
Hengchao Zhang
Yan Hou
Lei Sun
Hongdi Xu
Yuning Lv
Xiuyun Wu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1674470

990 views

Mini Review

Published on 14 Nov 2025

Liquid-liquid phase separation in super enhancer-driven oncogenesis: mechanisms, immune evasion, and therapeutic implications

in Epigenomics and Epigenetics

Ruoxi Yu
Deyu Sun
Chuang Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1645325

782 views

Review

Published on 07 Nov 2025

Chromatin remodeling complexes: architects influencing breast cancer progression

in Epigenomics and Epigenetics

Octavianus Giovani
Grace S. Eckersley
Hayden R. Jones
Sankari Nagarajan

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1690350

1,269 views

Review

Published on 05 Nov 2025

Structure, function, and pathology of PHF23

in Epigenomics and Epigenetics

Linlin Liu
Rui Zhang
Rui Liu
Yu Liu
Yanming Ren

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1691318

805 views

Original Research

Published on 30 Oct 2025

The earliest impact of restricted protein intake during pregnancy on heart development in male mouse offspring

in Epigenomics and Epigenetics

Marina S. Folguieri
Bruno Calsa
Patricia Aline Boer
José Antonio Rocha Gontijo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1678126

886 views

Mini Review

Published on 21 Oct 2025

Epitranscriptomic signatures in blood: emerging biomarkers for diagnosis of diabetes and its complications

in Epigenomics and Epigenetics

Marketa Hlavackova
Daniel Benak
Kristyna Holzerova
Petra Alanova
Jaroslav Hrdlicka
Miloslava Chalupova
Barbora Opletalova
Bohuslav Ostadal
Frantisek Kolar

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1656769

1,523 views

Mini Review

Published on 18 Sep 2025

Advancing therapeutic target discovery in pulmonary diseases: evolution and application of space exploration technologies

in Epigenomics and Epigenetics

Bo Yang
Quan Zheng
Guozheng Li
Bingnan Liao
Zhongxiao Lin
Hao He

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1657720

2,391 views

Original Research

Published on 16 Sep 2025

The value of fibroblast growth factor 21 (FGF21) promoter methylation in the repair and regeneration during the course of chronic hepatitis B

in Epigenomics and Epigenetics

Xue Li
Ying Zhang
Jihui Li
Tong Zhao
YuChen Fan
Shuai Gao
Kai Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1643250

1,915 views

Original Research

Published on 09 Sep 2025

Epigenetic modifications in developmental coordination disorder: association between DNA methylation and motor performance

in Epigenomics and Epigenetics

Fangfang Huang
Huizhen Li
Haizhen You
Yuantao Su
Huijuan Peng
Wenchong Du
Jing Hua

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1647365

2,343 views

Original Research

Published on 03 Sep 2025

The m6A demethylase FTO suppresses glioma proliferation by regulating the EREG/PI3K/Akt signaling pathway

in Epigenomics and Epigenetics

Yong Zhai
Caili Li
Lihui Cao
Shen Zhang
Xiao Liu
Junwei Ren
Yue Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1667990

2,422 views

Review

Published on 13 Aug 2025

Research progress on NAT10-mediated acetylation in normal development and disease

in Epigenomics and Epigenetics

Da Qin
Qing Liu
Xiaochao Ma
Rui Wang
Tianyu Lu
Yue Yang
Ze Tang
Yanbo Zhu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1623276

3,916 views