Frontiers in Chemical Biology

Perspective

Published on 29 Sep 2025

X-ray structures of metal-protein adducts at body temperature: concepts, examples and perspectives

in Bioinorganic Chemistry

Antonello Merlino

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1670177

192 views

Mini Review

Accepted on 24 Sep 2025

Metal in Medicine: Unlocking New Avenues for Neurodegenerative Disease Treatment

in Bioinorganic Chemistry

Kuan Teng Tan
Kok Whye Cheong
Lai Chun Wong
Helene C Bertrand
Nurul Huda Abd Karim
Yie Kie Chong
May Lee Low

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1696058

101 views

Correction

Published on 19 Sep 2025

Correction: An activity-based probe for antimicrobial target DXP synthase, a thiamin diphosphate-dependent enzyme

in Molecular Sciences

Lauren B. Coco
Caren L. Freel Meyers

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1670585

246 views

Editorial

Published on 19 Sep 2025

Editorial: Linking chemistry to biology and medicine via metal ions: developed from the 16th international symposium on applied bioinorganic chemistry

in Bioinorganic Chemistry

Christina N. Banti
Debbie C. Crans
Ana Maria Da Costa Ferreira
Sotiris K. Hadjikakou

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1695257

419 views

Perspective

Published on 04 Sep 2025

Lessons from metals-containing drugs in diagnostic, and theranostic applications for future development of metal-containing non-conventional therapeutics: vanadium compounds for intratumor administration

in Bioinorganic Chemistry

Adam R. Miller
Debbie C. Crans

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1639340

791 views

Original Research

Published on 14 Aug 2025

Preliminary investigation of Ru(II) complexes bearing nile red chromophores for photodynamic therapy

in Bioinorganic Chemistry

Claire Condon
Oriol Careta-Borràs
Judit Fodor
Amani B. Al Riyami
Xiao Xiao
Jianzhang Zhao
Carme Nogués
Sylvia M. Draper

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1620562

731 views

Original Research

Published on 12 Aug 2025

Carboxymethyl cellulose hydrogel doped with zinc-aspirinate as a multifunctional material: photoprotection, epithelial regeneration, and biocompatibility

in Bioinorganic Chemistry

Christina N. Banti
Fotakis Lezos
Antonios Hatzidimitriou
Sotiris K. Hadjikakou

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1639096

577 views

Editorial

Published on 15 Jul 2025

Editorial: Insights in theoretical modelling, structure prediction and design

in Theoretical Modeling, Structure Prediction & Design

Andrea Ilari
Veronica Morea
Adriana Erica Miele

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1653901

604 views

Brief Research Report

Published on 24 Jun 2025

Boronic acid-modified cell-penetrating peptide exhibits superior performance over natural TAT peptide

in Structure, Spectroscopy & Imaging

Pritam Ghosh

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1610127

1,438 views
1 citation

Specialty Grand Challenge

Published on 18 Jun 2025

Specialty grand challenges in theoretical modeling, structure prediction and design

in Theoretical Modeling, Structure Prediction & Design

Cécile Exertier
Andrea Ilari

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1635423

870 views

Original Research

Published on 17 Jun 2025

How vanadium and manganese compounds impact cardiac mitochondrial function

in Bioinorganic Chemistry

Connor C. Dolan
Luke A. Whitcomb
Edgar Del Carpio
Lilliana Rose
Adam J. Chicco
Debbie C. Crans

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1602602

1,271 views

Original Research

Published on 14 May 2025

Expanding the molecular landscape of fragments binding to trypanothione reductase, a legitimate target for drug design against human African trypanosomiasis

in Theoretical Modeling, Structure Prediction & Design

Cécile Exertier
Lorenzo Antonelli
Vittorio Brufani
Gianni Colotti
Andrea Ilari
Annarita Fiorillo

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1605579

1,378 views

Original Research

Published on 12 May 2025

Exploring the heterodimer MDM2/MDM4 interaction region uncovers high-affinity peptides for therapeutic p53-reactivation

in Theoretical Modeling, Structure Prediction & Design

Marika Attili
Sonia Valentini
Maria Pesavento
Marco Ballarotto
Viviana Scognamiglio
Alfredo Pontecorvi
Antonio Macchiarulo
Fulvio Saccoccia
Fabiola Moretti

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1576640

2,338 views

Original Research

Published on 23 Apr 2025

Structural and dynamical characterization of pRb, LTSV40 and the pRb-LTSV40 complex suggests a common mechanism for pRb inactivation

in Theoretical Modeling, Structure Prediction & Design

Carla Luciana Padilla Franzotti
Nicolas Palopoli
Juliana Palma
Gustavo Pierdominici-Sottile

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1538350

1,146 views

Editorial

Published on 03 Apr 2025

Editorial: New developments in bioinorganic and bioorganic chemistry

in Bioinorganic Chemistry

Isabel Correia
Sylvia M. Draper

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1586841

1,186 views

Mini Review

Published on 28 Feb 2025

Multifaceted roles of STING in tumors: from molecular mechanisms to therapeutic strategies

in Molecular Sciences

Aashiq Hussain
Linchun Wen
Rui Wang

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1549003

1,161 views