Frontiers in Chemical Biology

Original Research

Published on 06 Sep 2024

Exploring polyoxometalate speciation: the interplay of concentration, ionic strength, and buffer composition

in Bioinorganic Chemistry

Maja Ždrnja
Nadiia I. Gumerova
Annette Rompel

Frontiers in Chemical Biology

doi 10.3389/fchbi.2024.1444359

1,609 views

Review

Published on 19 Aug 2024

Bioluminescence from the bright and dark sides

in Quantitative and Analytical Techniques

Sung-Bae Kim
Tadaomi Furuta

Frontiers in Chemical Biology

doi 10.3389/fchbi.2024.1459397

2,966 views
4 citations

Original Research

Published on 13 Aug 2024

Expanding the applications of a bioluminescent mouse infection model of acute African trypanosomiasis

in Structure, Spectroscopy & Imaging

Diego Benítez
Cecilia Ortíz
Estefania Dibello
Marcelo A. Comini

Frontiers in Chemical Biology

doi 10.3389/fchbi.2024.1433511

1,377 views
1 citation

Original Research

Published on 12 Aug 2024

Guanidinium and spermidinium decavanadates: as small biomimetic models to understand non-covalent interactions between decavanadate and arginine and lysine side chains in proteins

in Bioinorganic Chemistry

Luis F. Paredes-Pérez
Angel Mendoza
Amalia García-García
Laura E. Serrano-De la Rosa
Miguel A. Méndez-Rojas
Francisco J. Melendez
María Eugenia Castro
Enrique González-Vergara

Frontiers in Chemical Biology

doi 10.3389/fchbi.2024.1451167

1,818 views
2 citations

Original Research

Published on 05 Aug 2024

Structural and kinetic characterization of DUSP5 with a Di-phosphorylated tripeptide substrate from the ERK activation loop

in Molecular Sciences

Andrea Imhoff
Noreena L. Sweeney
Robert D. Bongard
Raulia Syrlybaeva
Ankan Gupta
Edgar Del Carpio
Marat R. Talipov
Costanza Garcia-Keller
Debbie C. Crans
Ramani Ramchandran

Frontiers in Chemical Biology

doi 10.3389/fchbi.2024.1385560

1,488 views
2 citations

Original Research

Published on 31 Jul 2024

Generation of lysolipin derivatives by genetic engineering

in Molecular Sciences

Helene Robertsen
Sabrina Rohrer
Andreas Kulik
Wolfgang Wohlleben
Yvonne Mast

Frontiers in Chemical Biology

doi 10.3389/fchbi.2024.1445095

1,282 views

Original Research

Published on 29 Jul 2024

Development of SYK NanoBRET cellular target engagement assays for gain–of–function variants

in Molecular Sciences

Jacob L. Capener
James D. Vasta
Vittorio L. Katis
Ani Michaud
Michael T. Beck
Sabrina C. D. Daglish
Sarit Cohen-Kedar
Efrat Shaham Barda
Stefanie Howell
Iris Dotan

Frontiers in Chemical Biology

doi 10.3389/fchbi.2024.1447622

1,325 views

Original Research

Published on 23 Jul 2024

In silico enzyme screening identifies an SDR ketoreductase from Thermus caliditerrae as an attractive biocatalyst and promising candidate for protein engineering

in Theoretical Modeling, Structure Prediction & Design

Yvett Sosa
Bhav Kapur
Jessica Hurtak
Laura J. Kingsley
Hao Wu
Stefanie Gruber
Herbert Nar
Saad Khattabi
Jesus Seco Moral
Maria Fátima Lucas

Frontiers in Chemical Biology

doi 10.3389/fchbi.2024.1425501

2,434 views

Original Research

Published on 22 Jul 2024

Generation and preclinical evaluation of a human heavy-chain-only antibody recognizing the membrane-bound tumor-associated antigen mesothelin

in Structure, Spectroscopy & Imaging

Rick Janssens
Rien van Haperen
Michael van der Reijden
Alex Maas
Jingsong Wang
Frank Grosveld
Dubravka Drabek

Frontiers in Chemical Biology

doi 10.3389/fchbi.2024.1408621

2,955 views

Mini Review

Published on 12 Jul 2024

The chemistry of Formycin biosynthesis

in Molecular Sciences

Nigel G. J. Richards
James H. Naismith

Frontiers in Chemical Biology

doi 10.3389/fchbi.2024.1428646

1,443 views

Original Research

Published on 10 Jul 2024

A switch and a failsafe: KatG’s mechanism for preservation of catalase activity using a conformationally dynamic Arg and an active-site Trp

in Molecular Sciences

Hui Xu
Jessica R. Kenneson
Laura E. Minton
Douglas C. Goodwin

Frontiers in Chemical Biology

doi 10.3389/fchbi.2024.1431412

1,572 views

Original Research

Published on 05 Jul 2024

Solution chemistry and anti-proliferative activity against glioblastoma cells of a vanadium(V) complex with two bioactive ligands

in Bioinorganic Chemistry

Aviva Levina
Gonzalo Scalese
Dinorah Gambino
Debbie C. Crans
Peter A. Lay

Frontiers in Chemical Biology

doi 10.3389/fchbi.2024.1394645

1,054 views
5 citations

Original Research

Published on 17 Jun 2024

Development of bioluminescent reporter Trypanosoma cruzi and bioassay for compound screening

in Structure, Spectroscopy & Imaging

Cristina Quiroga
Marcelo Incerti
Diego Benitez
Eduardo Manta
Andrea Medeiros
Marcelo A. Comini

Frontiers in Chemical Biology

doi 10.3389/fchbi.2024.1423430

1,559 views
1 citation

Review

Published on 06 Jun 2024

Advances in human glutamine-hydrolyzing synthetases and their therapeutic potential

in Molecular Sciences

Wen Zhu
Alanya J. Nardone
Lucciano A. Pearce

Frontiers in Chemical Biology

doi 10.3389/fchbi.2024.1410435

2,485 views
1 citation

Mini Review

Published on 30 May 2024

Keto-enol tautomerism in the development of new drugs

in Structure, Spectroscopy & Imaging

Ana Paula Araujo de Oliveira
Camila Anchau Wegermann
Ana Maria Da Costa Ferreira

Frontiers in Chemical Biology

doi 10.3389/fchbi.2024.1400642

3,924 views
2 citations

Original Research

Published on 22 May 2024

Effect of pH on the thermostability and redox properties of cytochrome c552 from Wolinella succinogenes

in Structure, Spectroscopy & Imaging

Vitor H. Mordido
Marta S. P. Carepo
Cristina M. Cordas
Navendu Paul
Jörg Simon
Isabel Moura
Sofia R. Pauleta

Frontiers in Chemical Biology

doi 10.3389/fchbi.2024.1398105

1,063 views