ORIGINAL RESEARCH article
Front. Chem.
Sec. Molecular Liquids
Volume 13 - 2025 | doi: 10.3389/fchem.2025.1563560
This article is part of the Research TopicFrontiers in Chemistry: Rising Stars in ChinaView all articles
Study the anti sebum ability of foam in surfactant mixing system
Provisionally accepted
- 1Guangdong Pharmaceutical University, Guangzhou, China
- 2Emperor's Wisdom Skin and Biotechnology Institute, Guangzhou, China
- 3Zhengzhou University of Light Industry, Zhengzhou, Henan Province, China
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This investigation systematically elucidates the foam dynamics and consumer perception correlations within amino-acid-derived surfactant-mixed-component systems. pH-gradient experiments (5.5-10) coupled with dynamic foam analysis revealed that SLG-CAB (Sodium lauroyl glycinate-Cocamide propyl betaine ) blends accelerated foam nucleation kinetics from 35s to 20s/100mL (pH=8.5), exhibiting statistically significant correlation (p<0.001) with commercial rapid-foaming benchmarks (<5s initial foam formation). Molecular dynamics simulations identified robust intermolecular hydrogen bonds between CAB's ammonium protons and SLG's carboxamide oxygen (d=1.901 Å), achieving thermodynamic stabilization (ΔE=-53.04 kcal/mol) that enhanced film stability (Tfls 50% >5 min), thereby sustaining practical "prolonged creaminess" during cleansing.The SLG-CAB system demonstrated smaller bubble dimensions compared to SLS-CAB(Sodium lauroyl sarcosinate-Cocamide propyl betaine) formulations, generating monodisperse bubbles (primary diameter≈95 μm) that impart "velvety"sensory attributes. In lipid resistance evaluation, SLG-CAB systems attained 74.74% lipid solubilization efficiency at pH 7-8 (vs. 33.12% for SLG alone), demonstrating synergistic coefficients ( β ₛ = -2.822). Bridging cosmetic applications (facial cleansers, body washes) with surfactant engineering principles, this work establishes phasebehavior-guided formulation strategies for personal care products.
Keywords: foam, surfactant, cleaning, Amino - acid, Sebum
Received: 20 Jan 2025; Accepted: 28 May 2025.
Copyright: © 2025 Li, Zhang, Deng, Yin, Zhang and He. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Rourou Li, Guangdong Pharmaceutical University, Guangzhou, China
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