ORIGINAL RESEARCH article
Front. Chem.
Sec. Nanoscience
Volume 13 - 2025 | doi: 10.3389/fchem.2025.1584199
Sustainable Biosynthesis, Physiochemical Characterization, Cytotoxicity, and Antimicrobial Evaluation of Novel Chromium Oxide Nanoparticles
Provisionally accepted
Ezzat Elshazly1*
G Abd elfadeel2
Lihang Yang3Xiqi Li3Emad A Ewais1
Ahmed M Sadek1
Taher M Taha4Omar Fathy4
Omar Mohammad Atta4
Wenzong Liu3*- 1Faculty of Science, Al Azhar University, Cairo, Beni Suef, Egypt
- 2Plan, Assuit, Egypt
- 3Harbin Institute of Technology, Shenzhen, Shenzhen, Guangdong, China
- 4Al-Azhar University, Cairo, Cairo, Egypt
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
The biosynthesis of nanoparticles (NPs) has attracted significant interest due to their diverse biological applications. However, the potential for NPs synthesis using plant resources from the Vicia monantha Retz remains largely unexplored. Notably, this study marks the first use of this specific plant for the biosynthesis of chromium oxide nanoparticles (Cr 2 O 3 NPs). In the present study, the single phase of Cr 2 O 3 7 T increasing t 9 U -Visible Light Spectroscopy reveals that the samples are semiconductor materials according to the achieved values of Energy band-gab. The developed Cr 2 O 3 NPs did not show any toxicity towards NIH-3T3 fibroblasts. The results show that Cr 2 O 3 NPs have good antimicrobial activity against two bacterial strains (Escherichia coli and Staphylococcus aureus) and two fungal strains (Candida albicans and Aspergillus sp.) by producing clear inhibition zones of 0.26 cm, 0.21 cm, 0.28 cm, and 0.3 cm, respectively, after 24 h. The Cr₂ O₃ NPs exhibit successful green synthesis, notable biocompatibility, and antimicrobial properties, resulting in them being highly promising for various applications and opening up possibilities for nanoparticle utilization in antimicrobial systems.
Keywords: Structure properties, Optical properties, Cytotoxcicity, Antimicribial, phsical activity
Received: 27 Feb 2025; Accepted: 03 Sep 2025.
Copyright: © 2025 Elshazly, Abd elfadeel, Yang, Li, Ewais, Sadek, Taha, Fathy, Atta and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Ezzat Elshazly, Faculty of Science, Al Azhar University, Cairo, Beni Suef, Egypt
Wenzong Liu, Harbin Institute of Technology, Shenzhen, Shenzhen, Guangdong, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.