ORIGINAL RESEARCH article
Front. Chem.
Sec. Polymer Chemistry
Volume 13 - 2025 | doi: 10.3389/fchem.2025.1606995
This article is part of the Research TopicAdvances in Natural Macromolecules: Chemistry and Materials EngineeringView all articles
Engineering the Mechanical Characteristics of Regenerated Silk Fibroin Materials: The Impact of Chemical and Physical Modification Strategies
Provisionally accepted
- 1Clinical Innovation Research Center of Nantong University, Nantong, China
- 2Department of Pain and Ultrasonography, Nantong Hospital Affiliated to Nanjing University of Chinese Medicine, Nantong, Jiangsu Province, China
- 3Department of Imaging, Nantong Hospital Affiliated to Nanjing University of Chinese Medicine, Nantong, China
- 4School of Life Sciences, Nantong University, Nantong, Jiangsu Province, China
- 5Department of Imaging, Affiliated Hospital of Nantong University, Nantong, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
In this study, an in-depth exploration was conducted on the mechanical properties of regenerated silk fibroin (RSF) materials through diverse processing modalities, encompassing wet pressing, humidity treatments with varying levels, and the incorporation of plasticizers. Notably, these approaches induced substantial modifications in the mechanical properties of RSF materials. The elastic strength of RSF exhibited a wide range from 12.6 to 1644.8 MPa, the ultimate strength spanned from 0.12 to 42.63 MPa, and the maximum elongation at break fluctuated between 0.67 and 614.38%.Additionally, the mechanisms underlying the effects of these distinct treatment methods were meticulously investigated. This fundamental research not only provides crucial insights into the modulation of silk fibroin's mechanical properties but also holds significant promise for broadening its applications in the biomedical engineering domain, particularly in the pivotal fields of bone tissue and tendon regeneration.
Keywords: Regenerated silk fibroin, mechanical property, Plasticizer, chemical modification, natural polymer
Received: 09 Apr 2025; Accepted: 22 May 2025.
Copyright: © 2025 Guan, Ding, Xue and Zhao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Ye Xue, Clinical Innovation Research Center of Nantong University, Nantong, China
Jinli Zhao, Department of Imaging, Affiliated Hospital of Nantong University, Nantong, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.