Editorial: Applications of Nanomaterials for Novel Thermotherapy

S. Manjura Hoque^1*Chandan Srivastava²A. K. M. Akther Hossain³Navid B Saleh⁴

• ¹Materials Science Division, Atomic Energy Centre Dhaka, Dhaka, Bangladesh
• ²Indian Institute of Science Department of Materials Engineering, Bengaluru, India
• ³Bangladesh University of Engineering and Technology, Dhaka, Bangladesh
• ⁴University of texas at Austin, Austin, United States

CaFe12O19/MnFe2O4 composites were prepared by Ishtiaque Syed et al. [3], where they combined hard (CaFe12O19) and soft (MnFe2O4) magnetic phases utilizing a chemical coprecipitation method. Their goal was to incorporate into the hybrid the characteristics of both spinel and hexaferrites based on Mn and Ca. Their selection of such components in the hybrid materials are notable since both Mn and Ca are biocompatible and biodegradable. The physicochemical characteristics were assessed with X-ray diffraction, Fourier transform infrared spectroscopy, a physical properties measurement system, and transmission electron microscopy. A limited coercivity and small magnetization in the exchange coupled CaFe12O19/MnFe2O4 composite were observed. Striking results >50 °C maximum temperature and a specific loss power in the range of 50-350 W/g were reported. Cytotoxicity assessments on Vero cell lines indicated a remarkable survival rate of over 95% for the coated composites.In a comprehensive review, Jiayou Qiu et al. [4] discussed that tumor-specific antigens may be derived from a patient's own tumor cells or created through genetic mutations, which can serve as a cancer controlling strategy. Therefore, they argue that it is crucial to improve the way tumor-specific antigens are presented to immune cells in anti-tumor immunotherapy.Recent advancements in nanoscience have opened up new avenues for tumor immunotherapy. Engineered nanoparticles have gained significant attention for their advantageous and stable qualities. These NPs can efficiently encapsulate chemotherapy drugs and proteins, allowing for targeted delivery within the body. Common carriers include liposomes, polymeric nanoparticles, and metal nanoparticles. Developing smart NP delivery systems can further optimize antigen presentation, thereby potentially enhancing the immune response against tumors. The review summarizes current strategies for sourcing various tumor-specific antigens and examines how these antigens can be effectively delivered to immune cells through intelligent NPs to strengthen anti-tumor immunity. Additionally, we discuss the challenges and opportunities from a clinical translation viewpoint associated with boosting tumor immune responses through smart delivery of cancer controlling substances. The authors argue that this review will stimulate innovative approaches in cancer treatment using intelligent NPs and further advance the research landscape for cancer vaccines.