Frontiers in Genetics | Computational Genomics

Original Research

Published on 02 Oct 2025

Analyses of haplotypes of TLR2 and TLR3 genes for COVID-19 prognosis in a cohort of professionals who worked in the first pandemic wave in Belém-PA, Brazil

in Computational Genomics

Marcos Jessé Abrahão Silva
Luiza Raquel Tapajós Figueira
Daniele Melo Sardinha
Eliete Costa da Cruz
Natasha Cristina Oliveira Andrade
Sebastião Kauã De Sousa Bispo
Thiago Augusto Ferreira Dos Anjos
Everaldina Cordeiro Dos Santos
Ana Judith Pires Garcia
Luana Nepomuceno Gondim Costa Lima

Frontiers in Genetics

doi 10.3389/fgene.2025.1659269

291 views

Data Report

Published on 01 Oct 2025

Annotated genome of Aedes japonicus japonicus using a hybrid-assembly approach

in Computational Genomics

Friederike Reuss
Tilman Schell
Haruhiko Isawa
Shinji Kasai
Sven Klimpel
Ruth Müller
Markus Pfenninger
Judith Kochmann

Frontiers in Genetics

doi 10.3389/fgene.2025.1667262

1,020 views

Correction

Accepted on 29 Sep 2025

Correction: DeepRNAac4C: a hybrid deep learning framework for RNA N4-acetylcytidine site prediction

in Computational Genomics

Guohua Huang
Runjuan Xiao
Chunying Peng
Jinyun Jiang
Weihong Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1704319

196 views

Original Research

Accepted on 29 Sep 2025

Identification of key genes for heart failure in dilated cardiomyopathy in different populations

in Computational Genomics

Yue Yu
Chentian Xue
Dong Ji
Wei Sheng
Xiang Gao
Xize Wu
Chengyan Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1618390

225 views

Original Research

Published on 29 Sep 2025

Immune-molecular nexus in reproductive disorders: mechanisms linking POI and RSA

in Computational Genomics

Chen Chen
Xinyue Zhang
Wenxin Li
Yueqin Liu
Dan Zhao
Subo Zhang
Xiaolan Zhu

Frontiers in Genetics

doi 10.3389/fgene.2025.1652519

1,052 views

Original Research

Published on 25 Sep 2025

Cross-modal predictive modeling of multi-omic data in 3D airway organ tissue equivalents during viral infection

in Computational Genomics

Mostafa Rezapour
Patrick M. McNutt
David A. Ornelles
Stephen J. Walker
Sean V. Murphy
Anthony Atala
Metin Nafi Gurcan

Frontiers in Genetics

doi 10.3389/fgene.2025.1658577

1,411 views

Original Research

Accepted on 24 Sep 2025

GTAT-GRN: A graph topology-aware attention method with multi-source feature fusion for gene regulatory network inference

in Computational Genomics

Shuran Wang
Lilian Zhang
Lutao Gao
Rao Yao
Jie Cui
Linnan Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1668773

534 views

Original Research

Accepted on 22 Sep 2025

Identification of shared diagnostic genes between osteoporosis and Crohn’s disease through integrated transcriptomic analysis and machine learning

in Computational Genomics

Guirong Yi
Peng Zhou
Qinxu Yang
Maosheng Zhao
Qiaoqiao Yang
Shensong Li
Chenpo Dang

Frontiers in Genetics

doi 10.3389/fgene.2025.1609915

648 views

Original Research

Published on 22 Sep 2025

Identification of platelet function-related genes in STEMI patients

in Computational Genomics

Jingjing Zhu
Shuangya Yang
Qing Guo
Yifan Yang
Bei Shi

Frontiers in Genetics

doi 10.3389/fgene.2025.1651794

709 views

Original Research

Published on 19 Sep 2025

A hypergraph neural network for prioritizing Alzheimer’s disease risk genes

in Computational Genomics

Meng Ma
Chao Deng
Yan Liu
Qingqing Cao
Fang Liu
Yan Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1668200

1,070 views

Original Research

Published on 17 Sep 2025

Uncovering differential gene expression between mtRNA-positive and -negative osteosarcoma cells: implications beyond mitochondrial function

in Computational Genomics

Xiaoyuan Meng
Zhongcheng Han
Wuerkan Yeerken
Zhigang Wang
Le Ma
Hongbo Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1588581

1,104 views

Original Research

Published on 17 Sep 2025

BioSemAF-BiLSTM: a protein sequence feature extraction framework based on semantic and evolutionary information

in Computational Genomics

Zihan Zhang
Yixuan Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1616880

1,373 views

Original Research

Published on 17 Sep 2025

Genetic and in silico functional characterization of a novel structural variant in the PAH gene by long-reads sequencing and structural modeling

in Computational Genomics

Viviana Gallardo
Alexis Gaete
Jonathan Maldonado
Paulina Morales
Angela Peña
Valerie Hamilton
Víctor Faundes
Lorena Santa María

Frontiers in Genetics

doi 10.3389/fgene.2025.1669007

1,190 views

Original Research

Published on 12 Sep 2025

Dissecting and validation the biomarker of heart failure progression in patients with atherosclerosis by single-cell sequencing, bioinformatics, and machine learning

in Computational Genomics

Lihua Ni
Huabo Li
Juan Du
Ke Zhou
Fugui Zhang
Liankai Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1587274

1,205 views

Original Research

Accepted on 11 Sep 2025

HFTC: A Hierarchical Fungal Taxonomic Classification Model for ITS Sequences Using Low-Dimensional Embedding Features

in Computational Genomics

Jiawei Wang
Shaojie Qiao
Chao Wang
Dongsheng Xiang
Yangcheng Liao

Frontiers in Genetics

doi 10.3389/fgene.2025.1650244

583 views

Original Research

Published on 10 Sep 2025

Diphenyl pyridine intervention improves S. aureus-induced pneumonia by globally regulating transcriptome profile

in Computational Genomics

Wei Duan
Qingfeng Zhu
Hai Ci
Jingang Zhang
Zhiwei Tian
Wanyu Li
Zhengfu Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1624327

1,120 views