Frontiers in Immunology | Cytokines and Soluble Mediators in Immunity

Correction

Published on 18 Nov 2025

Correction: Mechanistic insights into IL-1β-mediated progression of tendinopathy

in Cytokines and Soluble Mediators in Immunity

Yuchi Zhang
Jiayue Wang
Fanbo Tang
Runzhi Xian
Huanhuan Zhang
Yanlin Yuan
Guiquan Chen
Guoqiang Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1736822

510 views

Original Research

Published on 17 Nov 2025

SPHK1-mediated M2 macrophage polarization drives TGF-β1-dependent thrombus fibrosis

in Cytokines and Soluble Mediators in Immunity

Xiaoyun Chen
Fajiu Li
Guofeng Ma
Haifeng Qiang
Maohe Chen
Shi Chen
Yedong Huang
Xingyue Lai
Qinghuang Lin
Chaosheng Deng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1681485

1,389 views

Review

Published on 17 Nov 2025

The pivotal role of cytokines in liver disease pathogenesis and therapeutic potential

in Cytokines and Soluble Mediators in Immunity

Li Li
Xuhua Li
Fan Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1694582

1,234 views

Original Research

Published on 14 Nov 2025

Human spinal enthesis comparative biology of IL-17F and IL-17A reveals greater T-cell IL-17F induction and IL-23 regulation

in Cytokines and Soluble Mediators in Immunity

Nicole McDermott
Ala Altaie
Tom Macleod
Charlie Bridgewood
Peter Loughenbury
Robert Dunsmuir
Almas Khan
Vishal Borse
Abhay Rao
Avneet Manghera

Frontiers in Immunology

doi 10.3389/fimmu.2025.1658325

1,793 views

Editorial

Published on 13 Nov 2025

Editorial: Cytokines, and biomarkers involved in the immunomodulation of pediatric cancers

in Cytokines and Soluble Mediators in Immunity

Alessandro Poggi
Gabriella Pietra
Ignazio Caruana
Francesca Romana Mariotti
Bruno Azzarone

Frontiers in Immunology

doi 10.3389/fimmu.2025.1713006

884 views

Original Research

Published on 07 Nov 2025

Reciprocal activation between M1 macrophages and trophoblasts through CXCL9/STAT1/ZEB1/CCL2 axis promotes recurrent spontaneous abortion

in Cytokines and Soluble Mediators in Immunity

Sisi Yan
Xiang Wang
Qiuji Wu
Jinli Ding
Hui Qiu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1629370

930 views

Mini Review

Published on 07 Nov 2025

Cytokine networks and therapeutic advances in systemic lupus erythematosus

in Cytokines and Soluble Mediators in Immunity

Zeping Chen
Shupei Liu
Rui Xie
Pan Zhang
Yue Feng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1680418

1,564 views

Original Research

Published on 06 Nov 2025

Interleukin-6 levels and their haplotypes are associated with serological autoantibodies status and clinical activity in rheumatoid arthritis

in Cytokines and Soluble Mediators in Immunity

Ma. Natividad Flores-Castro
Ramcés Falfán-Valencia
Olivia Briceño
Ilse Adriana Gutiérrez-Pérez
Oscar Zaragoza-García
Gloria Pérez-Rubio
Cristina Morales-Martínez
Iris Paola Guzmán-Guzmán

Frontiers in Immunology

doi 10.3389/fimmu.2025.1679644

1,229 views

Review

Published on 05 Nov 2025

Cytokines in sepsis: a critical review of the literature on systemic inflammation and multiple organ dysfunction

in Cytokines and Soluble Mediators in Immunity

Roberta Vella
Diego Panci
Francesco Carini
Ginevra Malta
Salvatore Vieni
Sabrina David
Giuseppe Davide Albano
Maria Puntarello
Stefania Zerbo
Antonina Argo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1682306

2,557 views

Original Research

Published on 04 Nov 2025

AIMing for survival: The impact of the free and total AIM concentration in septic patients

in Cytokines and Soluble Mediators in Immunity

Birte Dyck
Ulrich Bosch dos Santos
Corinna Müller
Hartmuth Nowak
Tim Rahmel
Lars Palmowski
Matthias Unterberg
Alexander Wolf
Alexander von Busch
Andrea Witowski

Frontiers in Immunology

doi 10.3389/fimmu.2025.1685119

1,062 views

Mini Review

Published on 04 Nov 2025

Roles of cytokine storm in sepsis progression: biomarkers, and emerging therapeutic strategies

in Cytokines and Soluble Mediators in Immunity

Weibin You

Frontiers in Immunology

doi 10.3389/fimmu.2025.1696366

1,980 views

Systematic Review

Published on 03 Nov 2025

CD137 in tuberculosis: a scoping review of an emerging immune checkpoint at the crossroads of diagnosis, prognosis, and therapy

in Cytokines and Soluble Mediators in Immunity

Nuraddin Nasir Goronyo
Bih H. Chendi
Shalena Naidoo
Novel N. Chegou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1682269

1,995 views

Review

Published on 31 Oct 2025

Mechanistic insights into IL-1β-mediated progression of tendinopathy

in Cytokines and Soluble Mediators in Immunity

Yuchi Zhang
Jiayue Wang
Fanbo Tang
Runzhi Xian
Huanhuan Zhang
Yanlin Yuan
Guiquan Chen
Guoqiang Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1657285

1,256 views

Mini Review

Published on 24 Oct 2025

The clinical utility of autoantibodies in systemic sclerosis: a review with a focus on cohort differences and standardization

in Cytokines and Soluble Mediators in Immunity

Kazuhiro Komura

Frontiers in Immunology

doi 10.3389/fimmu.2025.1691988

1,774 views

Original Research

Published on 23 Oct 2025

Disrupted macrophage autophagy as a driver of cell death and LPS-induced lethal shock in systemic inflammation

in Cytokines and Soluble Mediators in Immunity

Tarek Chekroune
Sandra Carignon
Meriem Taleb
Florence Savigny
Stéphanie Rose
Isabelle Maillet
Catherine Mura

Frontiers in Immunology

doi 10.3389/fimmu.2025.1610033

2,362 views

Original Research

Accepted on 22 Oct 2025

IL-6 as an integrative biomarker of residual inflammation and visceral adiposity in psoriasis: a VAI threshold-dependent model

in Cytokines and Soluble Mediators in Immunity

Eva Klara Merzel Šabović
Tadeja Kraner Šumenjak
Miodrag Janić

Frontiers in Immunology

924 views

Opinion

Published on 22 Oct 2025

Reframing chronic wound therapy: from growth factor delivery to regenerative immuno-engineering

in Cytokines and Soluble Mediators in Immunity

Zhiyong Wang
Xuan Zeng
Wenzhao Feng
Yanxin Lu
Pei Wei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1683591

1,121 views

Original Research

Published on 22 Oct 2025

Serum IL-17F as a biomarker of infection-independent cirrhosis progression

in Cytokines and Soluble Mediators in Immunity

Georgios Konstantis
Moritz Passenberg
Clara Guntlisbergen
Andreas Schütte
Björn Jung
Nargiz Nuruzade
Florian Seltsam
Dieter P. Hoyer
Jan Best
Katharina Willuweit

Frontiers in Immunology

doi 10.3389/fimmu.2025.1671288

1,459 views
1 citation

Review

Published on 21 Oct 2025

Advances in immunology of obstructive sleep apnea: mechanistic insights, clinical impact, and therapeutic perspectives

in Cytokines and Soluble Mediators in Immunity

Na Dong
Hongmei Yue

Frontiers in Immunology

doi 10.3389/fimmu.2025.1654450

2,216 views
1 citation

Original Research

Published on 20 Oct 2025

The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection

in Cytokines and Soluble Mediators in Immunity

Qi Dong
Jiejie Lu
Mengying Liu
Weiwei Wu
Yuying Kang
Ruijun Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1662183

1,184 views

Systematic Review

Published on 10 Oct 2025

Interleukin-18 in lupus nephritis: a meta-analysis of cytokine signaling dysregulation in immune-mediated nephropathy

in Cytokines and Soluble Mediators in Immunity

Cheng Zhou
Jiayi Li
Jing Zhao
Xue-Yuan Bai
Shunlai Shang
Wenge Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1631728

2,180 views

Original Research

Published on 08 Oct 2025

A crucial role of the malate aspartate shuttle in metabolic reprogramming in TNF-induced SIRS

in Cytokines and Soluble Mediators in Immunity

Louise Nuyttens
Marah Heyerick
Maxime Roes
Elise Moens
Céline Van Dender
Charlotte Wallaeys
Tino Hochepied
Steven Timmermans
Jolien Vandewalle
Claude Libert

Frontiers in Immunology

doi 10.3389/fimmu.2025.1652516

2,078 views

Systematic Review

Published on 08 Oct 2025

Immune and inflammatory mechanisms in asthma: insights into epigenetic modifications

in Cytokines and Soluble Mediators in Immunity

Haixia Fan
Bomeng Zhao
Huiyan Niu
Yan Li
Lu Zhai
Limantian Wang
Shudan Deng
Jie Gao
Xiaoling Gao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1677552

3,786 views

Original Research

Published on 08 Oct 2025

circWWC3 enhances the progression of triple-negative breast cancer by interacting with vimentin to regulate the secretion of CSF2

in Cytokines and Soluble Mediators in Immunity

Ming Wu
Yifan Du
Yuyang Dong
Yang Zheng
Lina Gu
Xiaojun Tang
Li Yan
Hong Ji
Yang Sang
Fei Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1665608

2,068 views

1,282 articles

articles

Correction: Mechanistic insights into IL-1β-mediated progression of tendinopathy

SPHK1-mediated M2 macrophage polarization drives TGF-β1-dependent thrombus fibrosis

The pivotal role of cytokines in liver disease pathogenesis and therapeutic potential

Human spinal enthesis comparative biology of IL-17F and IL-17A reveals greater T-cell IL-17F induction and IL-23 regulation

Editorial: Cytokines, and biomarkers involved in the immunomodulation of pediatric cancers

Reciprocal activation between M1 macrophages and trophoblasts through CXCL9/STAT1/ZEB1/CCL2 axis promotes recurrent spontaneous abortion

Cytokine networks and therapeutic advances in systemic lupus erythematosus

Interleukin-6 levels and their haplotypes are associated with serological autoantibodies status and clinical activity in rheumatoid arthritis

Cytokines in sepsis: a critical review of the literature on systemic inflammation and multiple organ dysfunction

AIMing for survival: The impact of the free and total AIM concentration in septic patients

Roles of cytokine storm in sepsis progression: biomarkers, and emerging therapeutic strategies

CD137 in tuberculosis: a scoping review of an emerging immune checkpoint at the crossroads of diagnosis, prognosis, and therapy

Mechanistic insights into IL-1β-mediated progression of tendinopathy

The clinical utility of autoantibodies in systemic sclerosis: a review with a focus on cohort differences and standardization

Disrupted macrophage autophagy as a driver of cell death and LPS-induced lethal shock in systemic inflammation

IL-6 as an integrative biomarker of residual inflammation and visceral adiposity in psoriasis: a VAI threshold-dependent model

Reframing chronic wound therapy: from growth factor delivery to regenerative immuno-engineering

Serum IL-17F as a biomarker of infection-independent cirrhosis progression

Advances in immunology of obstructive sleep apnea: mechanistic insights, clinical impact, and therapeutic perspectives

The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection

Interleukin-18 in lupus nephritis: a meta-analysis of cytokine signaling dysregulation in immune-mediated nephropathy

A crucial role of the malate aspartate shuttle in metabolic reprogramming in TNF-induced SIRS

Immune and inflammatory mechanisms in asthma: insights into epigenetic modifications

circWWC3 enhances the progression of triple-negative breast cancer by interacting with vimentin to regulate the secretion of CSF2