Frontiers in Immunology

Original Research

Published on 28 Jul 2025

CD4+ skin resident memory T cells preferentially colocalize with dermal Folr2hi macrophages in contact hypersensitivity

in Inflammation

Akihiko Murata
Koji Tokoyoda

Frontiers in Immunology

doi 10.3389/fimmu.2025.1590687

2,852 views

Original Research

Published on 28 Jul 2025

Hemopexin and HO-1 induction during acute colitis in mice is dependent on interleukin-22

in Inflammation

Ayodeji Samuel Ajayi
Claire Gerkins
Gabriela Fragoso
Annie Calvé
Manuela M. Santos

Frontiers in Immunology

doi 10.3389/fimmu.2025.1614466

2,488 views
1 citation

Original Research

Published on 24 Jul 2025

Integrated identification of immune-related therapeutic targets for interstitial cystitis via multi-algorithm machine learning: transcriptomic profiling and in vivo experimental validation

in Inflammation

Yifan Wang
Chuanzan Zhou
Facai Zhang
Yunkai Yang
Jia Miao
Xuanhan Hu
Xinyu Zhang
Alin Ji
Qi Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1636855

4,185 views

Original Research

Published on 24 Jul 2025

Photopharmacology reveals high-specificity linkage of Ca2+ entry at TRPC6 nanodomains to NFAT activation in mast cells

in Inflammation

Denis Krivić
Olga Panasiuk
Johannes Pilic
Roland Malli
Bernadett Bacsa
Sanja Ćurčić
Klaus Groschner

Frontiers in Immunology

doi 10.3389/fimmu.2025.1595036

2,307 views

Review

Published on 23 Jul 2025

Regulated programmed cell death in acute lung injury: from pathogenesis to therapy

in Inflammation

Shi-wen Liu
Yi-jian Chen
Yi Liu
Wen Zhou
Xuan Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1630015

4,853 views
4 citations

Brief Research Report

Published on 23 Jul 2025

Peripheral monocyte transcriptional signatures of inflammation and oxidative stress in Parkinson’s disease

in Inflammation

Aaron D. Thome
Jinghong Wang
Farah Atassi
Jason R. Thonhoff
Alireza Faridar
Weihua Zhao
David R. Beers
Eugene C. Lai
Stanley H. Appel

Frontiers in Immunology

doi 10.3389/fimmu.2025.1571074

4,366 views
2 citations

Review

Published on 23 Jul 2025

Mechanistic and therapeutic insights into the function of different cell death modalities in rheumatoid arthritis: emphasis on the crosstalk with non-coding RNAs

in Inflammation

Jianting Wen
Jian Liu
Lei Wan
Fanfan Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1620209

3,678 views
2 citations

Original Research

Published on 23 Jul 2025

Multi-organ pathology in a small porcine model of cytokine storm syndrome characteristics

in Inflammation

Jiaqian Jin
Linxiao Fan
Richai Chen
Xuanhao Lin
Sainan Zhang
Mengfei Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1618665

1,684 views
1 citation

Original Research

Published on 22 Jul 2025

Disease control and disease activity in hereditary angioedema: two sides of the same coin?

in Inflammation

Behzad Heibati
Jack Borle
Bruce Ritchie
Adil Adatia

Frontiers in Immunology

doi 10.3389/fimmu.2025.1631448

2,944 views

Mini Review

Published on 22 Jul 2025

Ferroptosis: a key driver and therapeutic target in the pathogenesis of acute respiratory distress syndrome

in Inflammation

Mingjun Yao
Jinfeng Liao
Zheng Liu
Wei Zhao
Siyuan Song
Xiaobo Huang
Yi Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1567980

5,240 views
2 citations

Original Research

Published on 22 Jul 2025

Regulation of hepatic Sirt1 expression and lipid metabolism through TNF receptor signaling

in Inflammation

Ian N. Hines
Samuel B. Stafford
Blair U. Bradford
Michael D. Wheeler

Frontiers in Immunology

doi 10.3389/fimmu.2025.1627433

2,808 views
1 citation

Brief Research Report

Published on 21 Jul 2025

Macrophage transfer promotes intestinal mucosal healing by encouraging transit-amplifying cell expansion in mice

in Inflammation

Dong su Kang
Young min Song
Yeon Ji Park
Hyeon Jong Jeong
Jung Joo Hong
Seung Hyeok Seok
Yi Rang Na

Frontiers in Immunology

doi 10.3389/fimmu.2025.1555695

4,046 views
2 citations

Original Research

Published on 21 Jul 2025

TREM-1 as a potential gatekeeper of neuroinflammatory responses: therapeutic validation and mechanistic insights in experimental traumatic brain injury

in Inflammation

Yunsheng Zhang
Yulian Zhang
Hanhan Dang
Chuanpeng Zhang
Kun He
Xu Yang
Zixi Wang
Li Zhang
Yanbing Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1636917

4,402 views
1 citation

Original Research

Published on 21 Jul 2025

Patients with peripheral artery disease demonstrate altered expression of soluble and membrane-bound immune checkpoints

in Inflammation

Rosanne D. Reitsema
Seta Kurt
Ignacio Rangel
Hans Hjelmqvist
Mats Dreifaldt
Allan Sirsjö
Ashok Kumar Kumawat

Frontiers in Immunology

doi 10.3389/fimmu.2025.1568431

2,065 views
1 citation

Review

Published on 18 Jul 2025

Multidimensional mechanisms and therapies underlying gastroesophageal reflux disease: focus on immunity, signaling pathways, and the microbiota-gut-brain axis

in Inflammation

Jiajing Zheng
Lin Tao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1629944

6,248 views
3 citations

Editorial

Published on 18 Jul 2025

Editorial: Community series in pathogenetic mechanism and therapeutic target for inflammation in autoimmune disease, volume II

in Inflammation

Jia Li
Minrui Liang
Hai-Feng Pan
Jian Gao
Yuekang Xu
Liangjing Lu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1645760

1,647 views

Original Research

Published on 18 Jul 2025

C-reactive protein induced T cell activation is an indirect monocyte-dependent mechanism involving the CD80/CD28 pathway

in Inflammation

Julia Thomé
Julia Limmer
Teresa Z. Brose
Johannes Zeller
Nina Chevalier
Anna-Lena Schäfer
Laura Schneider
Maike Lind
Thierry Christmann
Marie Dreck

Frontiers in Immunology

doi 10.3389/fimmu.2025.1622865

2,657 views
4 citations

Original Research

Published on 17 Jul 2025

Vitamin D ameliorates prediabetic cardiac injure via modulation of the ErbB4/ferroptosis signaling axis

in Inflammation

Yufan Miao
Yujing Zhang
Luoya Zhang
Hao Chen
Lulu Tang
Wenjie Li
Chenxi Gu
Lili Lang
Xing Li
Hanlu Song

Frontiers in Immunology

doi 10.3389/fimmu.2025.1626295

3,245 views

Review

Published on 17 Jul 2025

From laboratory to clinic: a precise treatment strategy of mesenchymal stem cells-derived exosomes pretreated by simulating disease microenvironment

in Inflammation

Hailian Ye
Qi He
Fang Qi
Guangchao Xu
Mulan Qahar
Chenliang Deng
Zairong Wei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1609288

3,495 views
1 citation

Original Research

Published on 17 Jul 2025

Exosome circ-CBLB promotes M1 macrophage polarization in rheumatoid arthritis through the TLR3/TRAF3 signaling axis

in Inflammation

Mengyu Zhang
Lei Wan
Xiaojun Zhang
Siyu Wang
Feng Li
Dawei Yan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1627389

4,142 views
2 citations

Review

Published on 17 Jul 2025

Research progress of PYK2 in digestive system diseases

in Inflammation

Yiyao Duan
Mingzhu Xie
Hui Wang
Sijing Chen
Jun Hu
Xujia Chen
Hong Ping Jia
Ningyan Zhang
Ling Peng
Xiang Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1614589

2,097 views

Original Research

Published on 16 Jul 2025

Frailty Index-laboratory and lymphocyte subset patterns in predicting 28-day mortality among elderly sepsis patients: a multicenter observational cohort study

in Inflammation

Dongkai Li
Jiatong Hou
Zhan Shi
Xiao Li
Jiahui Zhang
Guoyu Zhao
Xianli Lei
Yawen Xie
Yuefu Wang
Hao Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1624655

2,639 views

Review

Published on 16 Jul 2025

Ferroptosis and bone health: bridging the gap between mechanisms and therapy

in Inflammation

Renyan Xiao
Zhongyu Han
Peng Jia
Pei Li
Meng Gong
Yijin Cai
Lina Pang
Xiangyin Ye
Song Jin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1634516

3,052 views
7 citations

Original Research

Published on 16 Jul 2025

Identification of CTSC-driven progression in ESCC by single-cell sequencing and experimental validation

in Inflammation

Xin Sui
Yongxu Jia
Jing Li
Jiayao Xu
Wenjia Wang
Yanru Qin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1585139

3,125 views
1 citation

5,790 articles

articles

CD4+ skin resident memory T cells preferentially colocalize with dermal Folr2hi macrophages in contact hypersensitivity

Hemopexin and HO-1 induction during acute colitis in mice is dependent on interleukin-22

Integrated identification of immune-related therapeutic targets for interstitial cystitis via multi-algorithm machine learning: transcriptomic profiling and in vivo experimental validation

Photopharmacology reveals high-specificity linkage of Ca2+ entry at TRPC6 nanodomains to NFAT activation in mast cells

Regulated programmed cell death in acute lung injury: from pathogenesis to therapy

Peripheral monocyte transcriptional signatures of inflammation and oxidative stress in Parkinson’s disease

Mechanistic and therapeutic insights into the function of different cell death modalities in rheumatoid arthritis: emphasis on the crosstalk with non-coding RNAs

Multi-organ pathology in a small porcine model of cytokine storm syndrome characteristics

Disease control and disease activity in hereditary angioedema: two sides of the same coin?

Ferroptosis: a key driver and therapeutic target in the pathogenesis of acute respiratory distress syndrome

Regulation of hepatic Sirt1 expression and lipid metabolism through TNF receptor signaling

Macrophage transfer promotes intestinal mucosal healing by encouraging transit-amplifying cell expansion in mice

TREM-1 as a potential gatekeeper of neuroinflammatory responses: therapeutic validation and mechanistic insights in experimental traumatic brain injury

Patients with peripheral artery disease demonstrate altered expression of soluble and membrane-bound immune checkpoints

Multidimensional mechanisms and therapies underlying gastroesophageal reflux disease: focus on immunity, signaling pathways, and the microbiota-gut-brain axis

Editorial: Community series in pathogenetic mechanism and therapeutic target for inflammation in autoimmune disease, volume II

C-reactive protein induced T cell activation is an indirect monocyte-dependent mechanism involving the CD80/CD28 pathway

Vitamin D ameliorates prediabetic cardiac injure via modulation of the ErbB4/ferroptosis signaling axis

From laboratory to clinic: a precise treatment strategy of mesenchymal stem cells-derived exosomes pretreated by simulating disease microenvironment

Exosome circ-CBLB promotes M1 macrophage polarization in rheumatoid arthritis through the TLR3/TRAF3 signaling axis

Research progress of PYK2 in digestive system diseases

Frailty Index-laboratory and lymphocyte subset patterns in predicting 28-day mortality among elderly sepsis patients: a multicenter observational cohort study

Ferroptosis and bone health: bridging the gap between mechanisms and therapy

Identification of CTSC-driven progression in ESCC by single-cell sequencing and experimental validation