Frontiers in Immunology

Original Research

Published on 05 Jan 2026

Traumatic brain injury and post-injury sleep fragmentation differentially alter the microglial transcriptome

in Inflammation

Morgan A. Taylor
Rebecca Boland
Samuel Houle
Zoe M. Tapp
Amara C. Davis
Christopher Cotter
John F. Sheridan
Jonathan Godbout
Olga N. Kokiko-Cochran

Frontiers in Immunology

doi 10.3389/fimmu.2025.1689773

1,372 views

Original Research

Published on 05 Jan 2026

The metabolic-immune interface of obesity in Covid-19: a role for angiotensin ii and inflammatory cytokines

in Inflammation

Cíntia Maria Rodrigues
Juliane Duarte Santos
Bruna Carolina Chaves Garcia
Marcelo Henrique Fernandes Ottoni
Karine Beatriz Costa
Marina Luiza Baêta Costa
Vívian Gonzalez Figueiredo
Daniel Macedo
Danilo Bretas de Oliveira
Etel Rocha Vieira

Frontiers in Immunology

doi 10.3389/fimmu.2025.1729494

938 views

Review

Accepted on 02 Jan 2026

Roles of the integrated stress response in regulation of inflammatory reactions

in Inflammation

Xiaopei Cui
Fan Jiang
Guei-Sheung Liu
Junjun Liu
Yanqiu Xing

Frontiers in Immunology

215 views

Review

Published on 02 Jan 2026

GSDME in cardiovascular diseases: research system and contemporary progress

in Inflammation

Zhenzhen Yang
Zilong Luo
Han Zhang
Junjie Zong
Pinyan Huang
Yuqing Niu
Cheng Zhou
Song Wang
Dan Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1683116

1,398 views

Review

Published on 02 Jan 2026

Recent advances on Hippo-YAP pathway in skin diseases

in Inflammation

Xuxia Cai
Kexin Chen
Xiahong Li
Kaoyuan Zhang
Jiaxu Gu
Changbing Shen
Bo Yu
Cong Huang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1728064

1,722 views

Original Research

Published on 02 Jan 2026

Bronchial epithelial cell-derived extracellular vesicles drive inflammasome activation and NTHi infection in COPD

in Inflammation

Georgia Bateman
Hong Guo-Parke
Caitlyn Harvey
Aoife Rodgers
Anna Krasnodembskaya
Dermot Linden
Rabindra Tirouvanziam
Lee A. Borthwick
Andrew J. Fisher
Judith Coppinger

Frontiers in Immunology

doi 10.3389/fimmu.2025.1713012

1,813 views

Original Research

Published on 02 Jan 2026

Single-cell RNA sequencing unraveled immune-related expression heterogeneity and lymphoid cell development dysregulation in childhood asthma

in Inflammation

Danying Zhu
Guang Li
Lang Yuan
Zeyu Zeng
Na Dong
Chao Wang
Ming Chen
Lijian Xie
Guohui Ding
Libing Shen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1606650

1,413 views

Mini Review

Published on 02 Jan 2026

Mast cells in the bone marrow microenvironment

in Inflammation

Domenico Ribatti

Frontiers in Immunology

doi 10.3389/fimmu.2025.1738487

968 views

Original Research

Published on 02 Jan 2026

Complement-mediated and direct activation of human neutrophils induced by Premolis semirufa caterpillar toxins

in Inflammation

Joel J. M. Gabrili
Ângela A. A. Megale
Giselle Pidde
Trent M. Woodruff
Denise V. Tambourgi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1706235

1,314 views

Review

Published on 30 Dec 2025

The role of macrophages in vascular calcification: strategies for diagnosis and treatment

in Inflammation

Yingkun Sheng
Yue Qiu
Xiao Wang
Jingyi Shi
Ziyan Yin
Zile Zhang
Shipeng Jiang
Jian Zhang
Xiaoxiao Hu
Weiling Hong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1724464

2,201 views

Original Research

Accepted on 26 Dec 2025

Bioinformatics-Driven Insights: Rapamycin-Mediated CaMK2D Inhibition Alleviates Intestinal Ischemia-Reperfusion Injury

in Inflammation

Ruxiang Sheng
Yanqiu Liang
Huihong Zhang
Yonghe Lai
Haiyu Hong
Dingbang Huang
Dezhao Liu

Frontiers in Immunology

133 views

Correction

Published on 23 Dec 2025

Correction: Promotion of BST2 expression by the transcription factor IRF6 affects the progression of endometriosis

in Inflammation

Jixin Li
Yanan He
Yanjun Qu
Chengcheng Ren
Xiaotong Wang
Yan Cheng
Liyuan Sun
Xin Zhang
Guangmei Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1748838

1,299 views

Review

Published on 19 Dec 2025

Inflammasomes as the molecular hub of cardiovascular-metabolic-immune comorbidity networks

in Inflammation

Xingyu Qian
Jian Sun
Fei Li
Li Xu
Xingjian Hu
Nianguo Dong
Guangzhou Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1690443

2,095 views

Mini Review

Published on 19 Dec 2025

Viral reprogramming of glial metabolism as a driver of neuroinflammation

in Inflammation

Tamara Rodrigues
Gabriel Salles Beltrão
Heloísa Girardi
Aguinaldo R. Pinto

Frontiers in Immunology

doi 10.3389/fimmu.2025.1686774

2,528 views

Mini Review

Published on 19 Dec 2025

The dual role of thrombospondin-1 in inflammatory regulation during acute respiratory distress syndrome: a mini-review

in Inflammation

YaWen Zheng
Cong Liu
YaJun Li
WenFei Wang
QingLi Dou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1699900

1,500 views

Review

Published on 19 Dec 2025

From “metabolic storm” to “immune paralysis”: the dynamic evolution of macrophages and metabolism reprogramming in ARDS

in Inflammation

Jia Tang
Mi Yan
Mengchun Li
Zhangxue Hu
Kun Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1738713

2,204 views

Correction

Published on 19 Dec 2025

Correction: Targeting ferroptosis: novel therapeutic approaches and intervention strategies for kidney diseases

in Inflammation

Yanfang Luo
Muyang Long
Xueqin Wu
Liuting Zeng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1765613

1,445 views
1 citation

Correction

Published on 19 Dec 2025

Correction: FKBP5-CCL5 interaction promotes neuroinflammation and neuronal apoptosis in ischemic stroke by regulating the MAPK pathway and enhancing NET formation

in Inflammation

Zhongchen Li
Tengkun Yin
Hongyang Guo
Zhenxing Liu
Peijian Wang
Chao Liu
Qingbo Wang
Meng Zhang
Yilei Xiao
Jiyue Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1744810

1,147 views

Review

Published on 18 Dec 2025

Endometriosis as an immune-mediated disease: pathogenetic mechanisms and therapeutic strategies

in Inflammation

Sofia Shifon
Tamara Tyrinova
Tatyana Veretelnikova
Natalia Pasman
Elena Chernykh

Frontiers in Immunology

doi 10.3389/fimmu.2025.1727183

3,104 views

Review

Published on 18 Dec 2025

Mechanism analysis and intervention strategies of the inflammatory microenvironment in traumatic spinal cord injury

in Inflammation

Hou-yun Gu
Fei-xiang Lin
Ning Liu
Can-hua Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1692346

1,596 views

Review

Published on 17 Dec 2025

PANoptosis: a potential target of cardiomyopathy

in Inflammation

Mingli Sun
Changxu Lu
Jinwen Wei
Can Gao
Dan Dong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1704465

1,091 views

Review

Published on 17 Dec 2025

Targeting persistently activated inflammatory microenvironment to promote chronic wound healing

in Inflammation

Yuxuan Dai
Yu Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1708358

1,905 views

Original Research

Published on 17 Dec 2025

Unveiling novel therapeutic mechanisms of Xinfeng capsule: modulating the ALKBH5–m6A–LINC00968 axis to alleviate oxidative stress-driven NETosis in rheumatoid arthritis

in Inflammation

Yue Sun
Yang Li
Jian Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1707663

1,584 views

Review

Published on 17 Dec 2025

Nanocarrier-based delivery of siRNA therapeutics in rheumatoid arthritis: immune mechanisms and translational perspectives

in Inflammation

Longbin Bai
Peng Su

Frontiers in Immunology

doi 10.3389/fimmu.2025.1718256

2,046 views

5,774 articles

articles

Traumatic brain injury and post-injury sleep fragmentation differentially alter the microglial transcriptome

The metabolic-immune interface of obesity in Covid-19: a role for angiotensin ii and inflammatory cytokines

Roles of the integrated stress response in regulation of inflammatory reactions

GSDME in cardiovascular diseases: research system and contemporary progress

Recent advances on Hippo-YAP pathway in skin diseases

Bronchial epithelial cell-derived extracellular vesicles drive inflammasome activation and NTHi infection in COPD

Single-cell RNA sequencing unraveled immune-related expression heterogeneity and lymphoid cell development dysregulation in childhood asthma

Mast cells in the bone marrow microenvironment

Complement-mediated and direct activation of human neutrophils induced by Premolis semirufa caterpillar toxins

The role of macrophages in vascular calcification: strategies for diagnosis and treatment

Bioinformatics-Driven Insights: Rapamycin-Mediated CaMK2D Inhibition Alleviates Intestinal Ischemia-Reperfusion Injury

Correction: Promotion of BST2 expression by the transcription factor IRF6 affects the progression of endometriosis

Inflammasomes as the molecular hub of cardiovascular-metabolic-immune comorbidity networks

Viral reprogramming of glial metabolism as a driver of neuroinflammation

The dual role of thrombospondin-1 in inflammatory regulation during acute respiratory distress syndrome: a mini-review

From “metabolic storm” to “immune paralysis”: the dynamic evolution of macrophages and metabolism reprogramming in ARDS

Correction: Targeting ferroptosis: novel therapeutic approaches and intervention strategies for kidney diseases

Correction: FKBP5-CCL5 interaction promotes neuroinflammation and neuronal apoptosis in ischemic stroke by regulating the MAPK pathway and enhancing NET formation

Endometriosis as an immune-mediated disease: pathogenetic mechanisms and therapeutic strategies

Mechanism analysis and intervention strategies of the inflammatory microenvironment in traumatic spinal cord injury

PANoptosis: a potential target of cardiomyopathy

Targeting persistently activated inflammatory microenvironment to promote chronic wound healing

Unveiling novel therapeutic mechanisms of Xinfeng capsule: modulating the ALKBH5–m6A–LINC00968 axis to alleviate oxidative stress-driven NETosis in rheumatoid arthritis

Nanocarrier-based delivery of siRNA therapeutics in rheumatoid arthritis: immune mechanisms and translational perspectives