Frontiers in Immunology | Multiple Sclerosis and Neuroimmunology

Review

Published on 26 Aug 2025

Bidirectional crosstalk between microglia and serotonin signaling in neuroinflammation and CNS disorders

in Multiple Sclerosis and Neuroimmunology

Yangchen Zheng
Limin Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1646740

4,317 views
1 citation

Original Research

Published on 26 Aug 2025

Amygdala volume changes as a potential marker of multiple sclerosis progression: links to EDSS scores and PIRA

in Multiple Sclerosis and Neuroimmunology

Aleksandra Pogoda-Wesołowska
Ignacy Stachura
Nina Sługocka
Marta Kania-Pudło
Jacek Staszewski
Adam Stępień

Frontiers in Immunology

doi 10.3389/fimmu.2025.1640607

1,698 views
1 citation

Original Research

Published on 21 Aug 2025

Discovery and early validation of serum protein signatures in untreated multiple sclerosis patients: identification of candidate biomarkers for diagnosis and stratification

in Multiple Sclerosis and Neuroimmunology

Isabel Brichette-Mieg
Ana Alonso-Torres
Pablo Aliaga-Gaspar
José-Luis Rodríguez-Bada
Virginia Reyes-Garrido
Patricia Urbaneja-Romero
Carmen Muñoz
María Díaz-Sánchez
Elisa Martín-Montañez
María-del-Rosario Cabello-Porras

Frontiers in Immunology

doi 10.3389/fimmu.2025.1579045

1,989 views

Editorial

Published on 20 Aug 2025

Editorial: Use of big data and artificial intelligence in multiple sclerosis

in Multiple Sclerosis and Neuroimmunology

Liesbet M. Peeters
Axel Faes
Hans-Peter Hartung

Frontiers in Immunology

doi 10.3389/fimmu.2025.1679482

1,908 views

Original Research

Published on 19 Aug 2025

GM-CSF production by immune cells in steady state and autoimmune neuroinflammation mapped using fate reporting mice

in Multiple Sclerosis and Neuroimmunology

Gholamreza Azizi
Javad Rasouli
Hamed Naziri
Michael V. Gonzalez
James Garifallou
Guang-Xian Zhang
Bogoljub Ciric
Abdolmohamad Rostami

Frontiers in Immunology

doi 10.3389/fimmu.2025.1617074

2,720 views

Review

Published on 13 Aug 2025

Homer-3 antibody in autoimmune cerebellar syndromes: a potentially treatable mimic of MSA-C – A review

in Multiple Sclerosis and Neuroimmunology

Patryk Chunowski
Natalia Madetko-Alster
Piotr Alster

Frontiers in Immunology

doi 10.3389/fimmu.2025.1660587

2,848 views

Original Research

Published on 07 Aug 2025

Identification of cellular factors associated with inflammation and neurodegeneration in multiple sclerosis

in Multiple Sclerosis and Neuroimmunology

Alexander Rodero-Romero
José Ignacio Fernández-Velasco
Enric Monreal
Raquel Sainz-Amo
Roberto Álvarez-Lafuente
Manuel Comabella
Lluís Ramió-Torrentà
José M. García-Domínguez
Noelia Villarrubia
Susana Sainz de la Maza

Frontiers in Immunology

doi 10.3389/fimmu.2025.1648725

3,214 views
1 citation

Editorial

Published on 07 Aug 2025

Editorial: Microglia and tissue macrophages in pain

in Multiple Sclerosis and Neuroimmunology

Darian Mohsenin
Jessica Yu
Zhonghui Guan
Xiaobing Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1666972

1,590 views

Review

Published on 01 Aug 2025

Immunological microenvironment and targeted therapeutics in multiple sclerosis: new insights in crosstalk between immune niches and CNS

in Multiple Sclerosis and Neuroimmunology

Xiaodi Sun
Feng Zhang
Luojinyun Wang
Gyeore Lee
Sibo Yang
Daqiang Zhou
Bohao Chang
Bo Hu
Yifan Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1604987

3,910 views

Original Research

Published on 30 Jul 2025

Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers

in Multiple Sclerosis and Neuroimmunology

Wentong Li
Yiyi Zhang
Chuanhong Li
Mingyang Jiang
Dong Wang
Luomeng Chao
Yuxia Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1615540

2,958 views

Original Research

Published on 24 Jul 2025

Reduced tolerogenic factor sCD83 in NMOSD and relapsing MOGAD: a potential new therapeutic pathway

in Multiple Sclerosis and Neuroimmunology

Ariel Rechtman
Omri Zveik
Lyne Shweiki
Garrick Hoichman
Tal Friedman-Korn
Livnat Brill
Adi Vaknin-Dembinsky

Frontiers in Immunology

doi 10.3389/fimmu.2025.1620069

2,933 views
1 citation

Original Research

Published on 24 Jul 2025

Clinical characteristics of patients with GFAP-IgG coexisting with AQP4-IgG or MOG-IgG

in Multiple Sclerosis and Neuroimmunology

Qingchen Li
Xinyun Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1610486

2,447 views

Correction

Published on 24 Jul 2025

Correction: The P2X7R-antagonist AFC-5128 ameliorates chronic experimental autoimmune encephalomyelitis in a preventive and therapeutic paradigm

in Multiple Sclerosis and Neuroimmunology

Robert Hoffrogge
Anna Karachunskaya
Neele Heitmann
Steffen Haupeltshofer
Xiomara Pedreiturria
Katharina Klöster
Verian Bader
Konstanze F. Winklhofer
Michael Hamacher
Bert Klebl

Frontiers in Immunology

doi 10.3389/fimmu.2025.1652299

970 views

Original Research

Published on 24 Jul 2025

Single-nucleus RNA sequencing reveals the specific molecular signatures of myeloid cells responding to brain injury after microglial replacement

in Multiple Sclerosis and Neuroimmunology

Xiao-Yi Xiong
Haicheng Yuan
Ying Mu
Yi He
Fang Xie
Xiao-Shuang Feng
Jia-Xin Xie
Xin-Ru Pan
Yu-Fei Wang
Jian Gong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1625673

3,147 views
1 citation

Original Research

Published on 23 Jul 2025

Exploring the mycobiota in multiple sclerosis: its influence on disease development and progression

in Multiple Sclerosis and Neuroimmunology

Ane Otaegui-Chivite
Miriam Gorostidi-Aicua
Laura Martins-Almeida
Ainhoa Alberro
Leire Romarate
Idoia Mendiburu
Amaya Álvarez de Arcaya
Maialen Arruti
Tamara Castillo-Triviño
David Otaegui

Frontiers in Immunology

doi 10.3389/fimmu.2025.1625794

2,410 views

Original Research

Published on 04 Jul 2025

Subcortical shape biomarkers reveal limbic and basal ganglia damage in anti-LGI1 encephalitis

in Multiple Sclerosis and Neuroimmunology

Jianping Qiao
Zhishun Wang
Jiaxiang Xin
Shengjun Wang
Anning Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1623577

1,642 views

Editorial

Published on 03 Jul 2025

Editorial: Community series in trends in neuroimmunology: cross-talk between brain-resident and peripheral immune cells in both health and disease, volume II

in Multiple Sclerosis and Neuroimmunology

Suryanarayan Biswal
Janina E. Borgonovo
Carlos L. Freites
Verónica Martínez-Cerdeño
Rajnikant Mishra
Shashank K. Maurya
Estela M. Muñoz

Frontiers in Immunology

doi 10.3389/fimmu.2025.1644278

3,097 views
1 citation

Original Research

Published on 01 Jul 2025

T-cell repertoire correlates with cytokine imbalance in multiple sclerosis patients

in Multiple Sclerosis and Neuroimmunology

Lisa Weidner
Rodolphe Poupardin
Tobias Zrzavy
Sandra Laner-Plamberger
Georg Gratz
Tanja Eichhorn
Viktoria Weber
Paulus S. Rommer
Christof Jungbauer
Dirk Strunk

Frontiers in Immunology

doi 10.3389/fimmu.2025.1604452

2,648 views

Original Research

Published on 01 Jul 2025

Chronic ethanol administration exacerbates memory loss by altering N6-methyladenosine-mediated epigenetic signaling

in Multiple Sclerosis and Neuroimmunology

Yuanhang Liao
Fu Xu
Yuqing Yan
Sicheng Zhou
Na Liu
Baomin Dou
Nivetha Srinivasan
Weizheng Wang
Xiongwei Zhu
Jianghong Ye

Frontiers in Immunology

doi 10.3389/fimmu.2025.1455994

2,358 views

Original Research

Published on 30 Jun 2025

Longitudinal immune profiling following autologous hematopoietic stem cell transplantation in multiple sclerosis: insights into immune reconstitution and disease modulation

in Multiple Sclerosis and Neuroimmunology

Malin Müller
Ivan Pavlovic
Anna Wiberg
Joachim Burman

Frontiers in Immunology

doi 10.3389/fimmu.2025.1601223

3,041 views

Original Research

Published on 30 Jun 2025

Understanding the microbiome in autologous haemopoietic stem cell transplant for multiple sclerosis

in Multiple Sclerosis and Neuroimmunology

Jun Yin
Nadeem O. Kaakoush
Jennifer Massey
Mark Danta

Frontiers in Immunology

doi 10.3389/fimmu.2025.1590601

2,668 views

Original Research

Published on 26 Jun 2025

Adherence to therapeutic recommendation in relapsing-remitting multiple sclerosis patients

in Multiple Sclerosis and Neuroimmunology

Justyna Chojdak-Łukasiewicz
Aleksandra Kołtuniuk
Ewa Sawicka
Anna Pokryszko-Dragan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1545430

1,651 views
1 citation

Review

Published on 26 Jun 2025

Rational therapeutic targeting of myeloid cells in glioblastoma: challenges and perspectives

in Multiple Sclerosis and Neuroimmunology

Faruk Akay
Maya Saleh

Frontiers in Immunology

doi 10.3389/fimmu.2025.1472710

4,094 views

Review

Published on 19 Jun 2025

Role of meningeal lymphatic vessels in brain homeostasis

in Multiple Sclerosis and Neuroimmunology

Meng-Ying Zhao
Chao-Yuan Ye
Yuan-Cheng Liu
Xiao-Ming Wang
Jun-Cai Fu
Xin-Yuan Liu
Rui Zhu
Yi-Zhao Li
Qing Tian

Frontiers in Immunology

doi 10.3389/fimmu.2025.1593630

5,300 views
2 citations

1,480 articles

articles

Bidirectional crosstalk between microglia and serotonin signaling in neuroinflammation and CNS disorders

Amygdala volume changes as a potential marker of multiple sclerosis progression: links to EDSS scores and PIRA

Discovery and early validation of serum protein signatures in untreated multiple sclerosis patients: identification of candidate biomarkers for diagnosis and stratification

Editorial: Use of big data and artificial intelligence in multiple sclerosis

GM-CSF production by immune cells in steady state and autoimmune neuroinflammation mapped using fate reporting mice

Homer-3 antibody in autoimmune cerebellar syndromes: a potentially treatable mimic of MSA-C – A review

Identification of cellular factors associated with inflammation and neurodegeneration in multiple sclerosis

Editorial: Microglia and tissue macrophages in pain

Immunological microenvironment and targeted therapeutics in multiple sclerosis: new insights in crosstalk between immune niches and CNS

Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers

Reduced tolerogenic factor sCD83 in NMOSD and relapsing MOGAD: a potential new therapeutic pathway

Clinical characteristics of patients with GFAP-IgG coexisting with AQP4-IgG or MOG-IgG

Correction: The P2X7R-antagonist AFC-5128 ameliorates chronic experimental autoimmune encephalomyelitis in a preventive and therapeutic paradigm

Single-nucleus RNA sequencing reveals the specific molecular signatures of myeloid cells responding to brain injury after microglial replacement

Exploring the mycobiota in multiple sclerosis: its influence on disease development and progression

Subcortical shape biomarkers reveal limbic and basal ganglia damage in anti-LGI1 encephalitis

Editorial: Community series in trends in neuroimmunology: cross-talk between brain-resident and peripheral immune cells in both health and disease, volume II

T-cell repertoire correlates with cytokine imbalance in multiple sclerosis patients

Chronic ethanol administration exacerbates memory loss by altering N6-methyladenosine-mediated epigenetic signaling

Longitudinal immune profiling following autologous hematopoietic stem cell transplantation in multiple sclerosis: insights into immune reconstitution and disease modulation

Understanding the microbiome in autologous haemopoietic stem cell transplant for multiple sclerosis

Adherence to therapeutic recommendation in relapsing-remitting multiple sclerosis patients

Rational therapeutic targeting of myeloid cells in glioblastoma: challenges and perspectives

Role of meningeal lymphatic vessels in brain homeostasis