Frontiers in Immunology | Primary Immunodeficiencies

Case Report

Published on 26 May 2025

Case Report: Biliary hemorrhage by intrahepatic pseudoaneurysm and asymptomatic right coronary artery pseudoaneurysm in a patient with STAT3 hyper IgE syndrome

in Primary Immunodeficiencies

Daiki Fujita
Masahiro Ueki
Hiroshi Yamanaka
Kota Watanabe
Satoshi Yakuwa
Atsushi Manabe
Masafumi Yamada

Frontiers in Immunology

doi 10.3389/fimmu.2025.1601776

758 views

Case Report

Published on 19 May 2025

Fatal HLH in patients with X-linked lymphoproliferative disease 1 due to a novel variant in SH2D1A: case report

in Primary Immunodeficiencies

Oksana Boyarchuk
Alla Volokha
Nataliia Yarema
Olga Dyvoniak
Tetyana Tomashivska
Ivanna Shymanska
Halyna Makukh
Jolan E. Walter

Frontiers in Immunology

doi 10.3389/fimmu.2025.1602107

1,480 views

Mini Review

Published on 19 May 2025

The clinical and socioeconomic aspects of t-cell receptor excision circle based newborn screening for severe combined immunodeficiency in Southeast and East Asia

in Primary Immunodeficiencies

Noelle Yoo
Seongjin Kim
Jane Kim
Jong Gyun Ahn
Insoo Kang
Junghee J. Shin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1549768

1,077 views

Original Research

Published on 15 May 2025

Granulomatous lymphocytic interstitial lung disease in common variable immune deficiency: an in-depth clinical, immunological, functional and radiological exploration with a focus on its management, challenged by chronic CMV infection

in Primary Immunodeficiencies

Mattia Moratti
Gioacchino Schifino
Francesco Baccelli
Simona Ferrari
Elisabetta Magrini
Mirna Bassi
Aldo Guerrieri
Maurizio Zompatori
Marcello Lanari
Francesca Conti

Frontiers in Immunology

doi 10.3389/fimmu.2025.1589052

1,489 views

Original Research

Published on 14 May 2025

Real-world evidence of the effectiveness and utilization of subcutaneous C1INH long-term prophylaxis in patients with HAE in Spain and Germany

in Primary Immunodeficiencies

Marcus Maurer
Stefan Cimbollek
Maebh Kelly
Kyle Rodney
John Elliott
Eduardo LoboGuerrero
Markus Magerl

Frontiers in Immunology

doi 10.3389/fimmu.2025.1576235

1,462 views

Original Research

Published on 09 May 2025

The effects of postponing BCG vaccination on the risk of BCG-related complications among patients with severe combined immunodeficiency disease in Saudi Arabia

in Primary Immunodeficiencies

Amal Aldhaheri
Ohoud Alyabes
Suliman Aljumaah
Raghad Alhuthil
Raghad Alonazi
Shefa Alamoudi
Mohammed Alsuhaibani
Salem Alghamdi
Esam A. Albanyan
Sami Al-Hajjar

Frontiers in Immunology

doi 10.3389/fimmu.2025.1596963

1,969 views

Case Report

Published on 08 May 2025

EBV-positive diffuse large B cell lymphoma secondary to activated phosphoinositide 3 kinase δ syndrome type 1 (APDS1): a case report and literature review

in Primary Immunodeficiencies

Qiu-yuan Xiang
Min Zuo
Ji-Hao Zhou
Chun Feng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1583405

1,212 views

Case Report

Published on 05 May 2025

Case Report: CD40LG Arg203Ile variant underlies atypical phenotype of X-linked hyper IgM syndrome

in Primary Immunodeficiencies

Takuro Nishikawa
Dan Tomomasa
Atsushi Hijikata
Hiroshi Kasabata
Yasuhiro Okamoto
Hans D. Ochs
Hirokazu Kanegane

Frontiers in Immunology

doi 10.3389/fimmu.2025.1572791

1,092 views

Case Report

Published on 30 Apr 2025

Case Report: Activated PI3-kinase-δ syndrome and ovarian malignancies: a case series from the European ESID-APDS registry

in Primary Immunodeficiencies

Maria Pia Esposto
Nizar Mahlaoui
Hassan Abolhassani
Koen Van Aerde
Simone Cesaro
Anita Chandra
Stephan Ehl
Sven Kracker
Felipe Suarez
Vincent Barlogis

Frontiers in Immunology

doi 10.3389/fimmu.2025.1572194

1,480 views

Original Research

Published on 17 Apr 2025

Reappraisal of IgG subclass deficiencies: a retrospective comparative cohort study

in Primary Immunodeficiencies

Damla Dogru
Yagmur Dogru
Faranaz Atschekzei
Abdulwahab Elsayed
Natalia Dubrowinskaja
Diana Ernst
Torsten Witte
Vega Gödecke
Georgios Sogkas

Frontiers in Immunology

doi 10.3389/fimmu.2025.1552513

1,574 views

Brief Research Report

Published on 28 Mar 2025

Genome and transcriptome sequencing for inborn errors of immunity: a feasible multi-omics diagnostic approach

in Primary Immunodeficiencies

Marija Rozevska
Katrina Daila Neiburga-Vigante
Inga Nartisa
Zane Lucane
Lota Ozola
Livija Bardina
Inta Jaunalksne
Natalija Gerula
Petra Krike
Gita Taurina

Frontiers in Immunology

doi 10.3389/fimmu.2025.1510365

2,223 views

Case Report

Published on 21 Mar 2025

Case Report: Hydroa vacciniforme-like lymphoproliferative disorder, an EBV-associated disease, successfully treated with hematopoietic stem cell transplantation

in Primary Immunodeficiencies

Eduardo Liquidano-Perez
Gibert Maza-Ramos
Marco Yamazaki-Nakashimada
Rodolfo Rodríguez-Jurado
Alfonso G. Ramírez Ristori
Juan Carlos Bustamante-Ogando
Mario Ernesto Cruz-Munoz
Arturo Gutierrez-Guerrero
Marimar Saez-de-Ocariz
Sara Espinosa-Padilla

Frontiers in Immunology

doi 10.3389/fimmu.2025.1511385

1,666 views

Mini Review

Published on 20 Mar 2025

Patient-reported outcomes with subcutaneous immunoglobulin in secondary immunodeficiency

in Primary Immunodeficiencies

Juthaporn Cowan
Il-Kang Na
André Gladiator
Marta Kamieniak
S. Shahzad Mustafa

Frontiers in Immunology

doi 10.3389/fimmu.2025.1528414

2,494 views

Case Report

Published on 18 Mar 2025

Case Report: Infection with Streptococcus constellatus manifesting as gelatinous pleural effusion in an HIV-positive patient

in Primary Immunodeficiencies

Zhongxia Yang
Wanyuan Xiong
Zibing Qian
Xiaorong Mao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1545165

908 views

Case Report

Published on 07 Mar 2025

Case Report: A novel IKBKB variant (c.1705G>T) is associated with immune dysregulation and disseminated tuberculosis

in Primary Immunodeficiencies

Gabriel Emmanuel Arce-Estrada
Miguel Rodríguez-Morales
Selma Cecilia Scheffler-Mendoza
Marimar Sáez-de-Ocariz
Laura Berrón-Ruiz
Sara Elva Espinosa-Padilla
Francisco Alberto Contreras-Verduzco

Frontiers in Immunology

doi 10.3389/fimmu.2025.1541899

1,345 views
1 citation

Review

Published on 07 Mar 2025

Multidisciplinary approach to treating complex immune dysregulation disorders: an adaptive model for institutional implementation

in Primary Immunodeficiencies

Lauren A. Henderson
Roshini S. Abraham
Aisha Ahmed
Lindsey Blount
Scott W. Canna
Natalia S. Chaimowitz
Shanmuganathan Chandrakasan
Bria Coates
James A. Connelly
Megan A. Cooper

Frontiers in Immunology

doi 10.3389/fimmu.2025.1519955

1,817 views
2 citations