Frontiers in Immunology | Vaccines and Molecular Therapeutics

Original Research

Published on 31 Jul 2025

Dose-sparing effects of novel adjuvants and aluminum hydroxide on two different vaccines in a neonatal mouse model

in Vaccines and Molecular Therapeutics

Jenny Lorena Molina Estupiñan
Poorya Foroutan Pajoohian
Gabriel Kristian Pedersen
Dennis Christensen
Serena Marchi
Emanuele Montomoli
Stefanía P. Bjarnarson
Ingileif Jonsdottir
Audur Anna Aradottir Pind

Frontiers in Immunology

doi 10.3389/fimmu.2025.1646677

1,032 views

Original Research

Published on 31 Jul 2025

Fc-modification of anti-PcrV gene-encoded antibodies modulates complement-mediated killing of Pseudomonas aeruginosa

in Vaccines and Molecular Therapeutics

Jillian Eisenhauer
Spencer Dublin
Jihae Choi
Abigail R. Trachtman
Jacqueline D. Chu
David Custodio-Zegarra
Suman Bharti
Bhavya Bhardwaj
Shuangyi Bai
William T. Witt

Frontiers in Immunology

doi 10.3389/fimmu.2025.1618297

994 views

Original Research

Published on 31 Jul 2025

MDSC depletion during immunization with heat-killed Mycobacterium tuberculosis increases protection against BCG infection

in Vaccines and Molecular Therapeutics

Arpa Aintablian
Anna M. Arold
Haisam Alattar
Laura Cyran
Christoph Schoen
Nelita Du Plessis
Gerhard Walzl
Ulrich Schaible
Andreas Beilhack
Natalie E. Nieuwenhuizen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1646526

762 views

Review

Accepted on 30 Jul 2025

Molecular ingredients of an immunogen for long-lasting IgG

in Vaccines and Molecular Therapeutics

Sneh Lata Gupta
Alexander R Meyer
Erika Kay-Tsumagari
Wei Cheng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1639371

182 views

Review

Published on 30 Jul 2025

BCG and beyond: unlocking new frontiers in TB vaccine development

in Vaccines and Molecular Therapeutics

Aishwarya Shaji
Akanksha Verma
Ashima Bhaskar
Ved Prakash Dwivedi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1608104

950 views

Original Research

Accepted on 28 Jul 2025

A genome-wide association study identifies new loci associated with response to SARS-CoV-2 mRNA-1273 vaccine in a cohort of healthy healthcare workers

in Vaccines and Molecular Therapeutics

Antonio José Cabrera-Serrano
Lucía Ruiz-Durán
Juan Francisco Gutiérrez Bautista
María Carretero Fernández
Rob ter Horst
Yang Li
Fernando Jesús Reyes-Zurita
Francisco José García Verdejo
Mihai Netea
Pedro Sánchez-Rovira

Frontiers in Immunology

doi 10.3389/fimmu.2025.1639825

223 views

Brief Research Report

Published on 28 Jul 2025

Hypertension attenuates COVID-19 vaccine protection in elderly patients: a retrospective cohort study

in Vaccines and Molecular Therapeutics

Zhen Yuan
Iong Fong Wong
Ren-He Xu
Xiao Zhan Zhang
Chon Lok Lei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1612205

1,020 views

Original Research

Published on 28 Jul 2025

Mixed lipopeptide-based mucosal vaccine elicits a long-term bone marrow memory response that is potentially cross-reactive against a broad-spectrum of coronaviruses in mice

in Vaccines and Molecular Therapeutics

Raj S. Patel
Babita Agrawal

Frontiers in Immunology

doi 10.3389/fimmu.2025.1619882

1,266 views

Original Research

Published on 25 Jul 2025

Integrating bioinformatics to explore HPV-31 and HPV-52 E6/E7 proteins: from structural analysis to antigenic epitope prediction

in Vaccines and Molecular Therapeutics

Qixue Cai
Yifan Feng
Wenbo Dong
Yanling Meng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1561572

900 views

Original Research

Published on 24 Jul 2025

AS04 drives superior cross-protective antibody response by increased NOTCH signaling of dendritic cells and proliferation of memory B cells

in Vaccines and Molecular Therapeutics

Valentino D’Onofrio
Ana Carolina Santana
Marthe Pauwels
Gwenn Waerlop
Anthony Willems
Fien De Boever
Martin Müller
Peter Sehr
Tim Waterboer
Isabel Leroux-Roels

Frontiers in Immunology

doi 10.3389/fimmu.2025.1623405

992 views

Original Research

Accepted on 22 Jul 2025

mRNA-based SARS-CoV-2 vaccines: The intracellular aggregation of encoded spike monomers and their subunits as a cause of cardiac side effects

in Vaccines and Molecular Therapeutics

Rolf Schreckenberg
Nadine Woitasky
Nadja Itani
Laureen Czech
Anita Cornelia Windhorst
Malte Juchem
Christian Bär
Thomas Thum
Péter Ferdinandy
Rainer Schulz

Frontiers in Immunology

doi 10.3389/fimmu.2025.1635478

14,522 views

Original Research

Published on 22 Jul 2025

Development and characterization of the genotype F attenuated mumps candidate strains

in Vaccines and Molecular Therapeutics

Hongtao Liu
Na Liu
Yueqiu Sun
Shuang Li
Hang Li
Menghan Wang
Hui Shuang
Yan Cai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1629585

1,021 views

Original Research

Published on 22 Jul 2025

Non-cognate ligands of hepatitis C virus envelope broadly neutralizing antibodies induce virus-neutralizing sera in mice

in Vaccines and Molecular Therapeutics

Stephen Ian Walimbwa
Shiv Bharadwaj
Petr Kosztyu
Lucie Vankova
Milan Kuchar
Eliska Kopecna
Roman Effenberg
Lukas Drasar
Leona Raskova Kafkova
Petr Maly

Frontiers in Immunology

doi 10.3389/fimmu.2025.1624299

1,083 views

Methods

Accepted on 21 Jul 2025

CoreTIA: a modular, statistically robust transduction inhibition assay for AAV neutralization

in Vaccines and Molecular Therapeutics

Beatrix Kovács
Fanni Somogyi
Viktória Szabó
Zoltan Zsolt Nagy
Istvan Hernadi
Ferenc Matyas
Wim Vanduffel
Zsuzsanna Szemlaky
Balázs Rózsa
István Ulbert

Frontiers in Immunology

doi 10.3389/fimmu.2025.1623848

134 views

Original Research

Published on 21 Jul 2025

MetE: a promising protective antigen for tuberculosis vaccine development

in Vaccines and Molecular Therapeutics

Salem Salman Almujri
Elena Stylianou
Annalisa Nicastri
Iman Satti
Marcellus Korompis
Shuailin Li
Christopher J. De Voss
Marco Polo Peralta Alvarez
Rachel Tanner
Paulo J. G. Bettencourt

Frontiers in Immunology

doi 10.3389/fimmu.2025.1593263

1,737 views

Original Research

Accepted on 17 Jul 2025

Investigation on antigen-specific T cell responses induced by Outer Membrane Vesicles from Escherichia coli Δ60 strain

in Vaccines and Molecular Therapeutics

Michele Tomasi
Lorenzo Croia
Ilaria Zanella
Assunta Gagliardi
Giulia Boscato Sopetto
Mattia Benedet
Gabriele di Lascio
Gaia Gambini
Alvise Berti
Riccardo Corbellari

Frontiers in Immunology

doi 10.3389/fimmu.2025.1633961

366 views