Toward a Roadmap for Addressing Today's Health Dilemma -The 101-Statement Consensus Report

Katharina C. Wirnitzer^1*Mohamad Motevalli²Derrick Tanous²Clemens Drenowatz³Maximilian Moser⁴Holger Cramer⁵Thomas Rosemann⁶Karl-Heinz Wagner⁷Andreas Michalsen⁸Beat Knechtle⁶Zlatko Fras⁹Merel Ritskes-Hoitinga¹⁰Adilson Marques¹¹Nataša Fidler Mis¹²Fatima Cody Stanford, MD, MPH, MPA, MBA, FAAP, FACP, FAHA, FAMWA, FTOS¹³Christian Schubert¹⁴Nandu Goswami⁴Claus - Leitzmann¹⁵Per Morten Fredriksen¹⁶Gerhard Ruedl²Doris Wilflingseder¹⁴Rodrigo Antunes Lima¹⁷Christian S. Kessler⁸Michael Jeitler⁸Naim Akhtar Khan¹⁸Hassan Joulaei¹⁹Maryam Fatemi¹⁹Andrew Knight²⁰Karl W. Kratky⁷Kara K Palmer²¹Bernd Haditsch²²Bostjan Jakse²³Walter Kofler¹⁴Tomas Pfeiffer²⁴Kathya Lorena Cordova-Pozo²⁵PATRIZIA TORTELLA²⁶Simon Straub²⁷Heidi Lynch²⁸Manuel Schätzer²⁹Anupama Krishnan³⁰Shahnaz Fathima³⁰Lukas Gatterer³¹Fabian Kriwan²⁷Mittal Abhishek³²Hemant Nandgaonkar³³Shalaka Nandgaonkar³⁴Abiola O. Adedara³⁵Josep Maria Haro³⁶Corina Gericke³⁷Gaby Neumann³⁷Aysha Akhtar³⁸Amir Rashidlamir³⁹Madan Thangavelu⁴⁰Ngoumou Gonza⁴¹Éva Perpék⁴²Michael Klaper⁴³Bhaswati Bhattacharya⁴⁴Werner Kirschner²Kathelijne Bessems⁴⁵Peter Jones⁴⁶Gregory E Peoples⁴⁷Raul Bescos⁴⁸Christina Duftner¹⁴Georg Johannes Seifert⁴¹

• ¹Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
• ²Universitat Innsbruck, Innsbruck, Austria
• ³Padagogische Hochschule Oberosterreich, Linz, Austria
• ⁴Medizinische Universitat Graz Otto Loewi Forschungszentrum fur Gefasbiologie Immunologie und Entzundung, Graz, Austria
• ⁵Universitatsklinikum Tubingen Universitats-Frauenklinik, Tübingen, Germany
• ⁶Universitat Zurich, Zürich, Switzerland
• ⁷Universitat Wien, Vienna, Austria
• ⁸Immanuel Krankenhaus Berlin Standort Berlin-Wannsee, Berlin, Germany
• ⁹Univerzitetni klinicni center Ljubljana, Ljubljana, Slovenia
• ¹⁰Universiteit Utrecht, Utrecht, Netherlands
• ¹¹Universidade de Lisboa, Lisbon, Portugal
• ¹²Ministry of Health, Ljubljana, Slovenia
• ¹³Harvard Medical School, Boston, United States
• ¹⁴Medizinische Universitat Innsbruck, Innsbruck, Austria
• ¹⁵Justus Liebig Universitat Giessen Zweigbibliothek im Zeughaus, Giessen, Germany
• ¹⁶Høgskolen i Innlandet, Lillehammer, Norway
• ¹⁷Universidad Autonoma de Madrid, Madrid, Spain
• ¹⁸Universite Bourgogne Europe, Dijon, France
• ¹⁹Shiraz University of Medical Sciences, Shiraz, Iran
• ²⁰Griffith University, Nathan, Australia
• ²¹University of Michigan, Ann Arbor, United States
• ²²Osterreichische Gesundheitskasse, Graz, Austria
• ²³Slovenian Strategic Council for Nutrition, Ljubljana, Slovenia
• ²⁴Institute for TCIM/CAM, Prague, Czechia
• ²⁵Radboud Universiteit, Nijmegen, Netherlands
• ²⁶Universita degli Studi di Enna 'Kore', Enna, Italy
• ²⁷Landeskrankenhaus Innsbruck Universitatskliniken, Innsbruck, Austria
• ²⁸Point Loma Nazarene University, San Diego, United States
• ²⁹Special Institute for Preventive Cardiology and Nutrition (SIPCAN), Elsbethen, Austria
• ³⁰Kerala University of Health Sciences, Thrissur, India
• ³¹Universitatsklinikum St Polten, St Pölten, Austria
• ³²Amity University, Uttar Pradesh, India
• ³³Maharashtra University of Health Sciences, Nashik, India
• ³⁴Occupational Therapy, Hands On Therapy Concepts, Mumbai, India
• ³⁵Institute of Human Virology Nigeria, Abuja, Nigeria
• ³⁶Universitat de Barcelona, Barcelona, Spain
• ³⁷Doctors Against Animal Experiments (DAAE), Cologne, Germany
• ³⁸Center for Contemporary Sciences (CCS), Gaithersburg, United States
• ³⁹Ferdowsi University of Mashhad, Mashhad, Iran
• ⁴⁰Ayush Valley Foundation, Kerala, India
• ⁴¹Charite - Universitatsmedizin Berlin, Berlin, Germany
• ⁴²Hungarian Academy of Sciences Centre of Excellence, Budapest, Hungary
• ⁴³Moving Medicine Forward, Medical School Nutrition Education Initiative, Peterburg, United States
• ⁴⁴Weill Cornell Medicine, New York, United States
• ⁴⁵Universiteit Maastricht, Maastricht, Netherlands
• ⁴⁶NHS, Wigan, United Kingdom
• ⁴⁷University of Wollongong, Wollongong, Australia
• ⁴⁸University of Plymouth, Plymouth, United Kingdom

Importance: Over the past decades, there has been an expansion in the quantity and quality of scientific findings and guidelines on different health topics to promote individual and public health status. Reports also indicate that there has been a simultaneous increase in the financial burden of disease, including trillions spent on healthcare resources by governments worldwide (predominantly in developing countries) to address health concerns. At the same time, personal health behavior is well-known as efficient and cost-free, holding four times the potential to prevent early death compared to health care. Despite this knowledge, data show that the increasing prevalence of unhealthy lifestyles and the associated chronic diseases, especially in Western societies, still need to be controlled. This circumstance exemplifies today`s global health dilemma, which alarms the inadequacy of ongoing efforts to address the existing health concerns worldwide. Setting, Insights and Observations: Three international, multidisciplinary, and inter-university events (two scientific conferences and one tertiary education symposium) were held in Austria (Innsbruck) between 2020 and 2022 to discourse, discuss, and debate these concerns. Two hundred eighty-four experts from 76 universities, organizations, and stakeholders spanning 31 nations and five continents participated in this international research and knowledge exchange to address today´s global health dilemma. The latest scientific findings were discussed to develop practical strategies for improving lifestyle behavior and focus on the dual "Healthy Eating & Active Living" approach as a minimum recommendation for sustainable lifelong health and care. The expert panel debated crucial research priorities and future policies, identified gaps and untapped potential in basic health approaches that have been grossly neglected, and approved the evidence-based 101 consensus statements presented. Conclusions and Relevance: These endeavors aim to develop novel and effective interventions that address the needs of individuals and communities and promote optimal health status.