Frontiers in Oncology | Cancer Molecular Targets and Therapeutics

Original Research

Published on 23 May 2025

Upregulation of stomatin is associated with poor prognosis and promotes tumor progression of orbital diffuse large B-cell lymphoma

in Cancer Molecular Targets and Therapeutics

Wen Chen
Jingyi Chi
Weichen Song
Xiuyun Li
Jinlei Ma
Xinyu Liu
Lihua Xiao
Wenwen Zhu

Frontiers in Oncology

doi 10.3389/fonc.2025.1596614

288 views

Original Research

Accepted on 22 May 2025

Prognostic Alternative mRNA Splicing in Lung Adenocarcinoma

in Cancer Molecular Targets and Therapeutics

Panke Su
Pei Xu
Deying Xu

Frontiers in Oncology

doi 10.3389/fonc.2025.1579017

Original Research

Published on 22 May 2025

CD46 TREM1 regulates the autophagy marker LC3B ATG5 in oral squamous cell carcinoma

in Cancer Molecular Targets and Therapeutics

Xiaodan Liu
Fumin Zheng
Meihua Gao
Yuanfei Wang
Xiaofang Lv
Beibei Cong
Wanchun Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1579282

408 views

Original Research

Published on 22 May 2025

Analysis of risk factors in breast cancer patients with hand-foot syndrome and oral mucositis caused by pegylated liposomal doxorubicin

in Cancer Molecular Targets and Therapeutics

Xianghua Quan
Jing Li
Jialin Sun
Xiaomin Xing
Donghua Liu
Hongyan Ji
Qie Guo

Frontiers in Oncology

doi 10.3389/fonc.2025.1564681

301 views

Original Research

Accepted on 21 May 2025

S100A11 as an Immune-Related Exosomal Driver of Colorectal Cancer Progression: A Novel Diagnostic Biomarker

in Cancer Molecular Targets and Therapeutics

Haibo Wang
Rongchao He
Deng Liu
Jun He
Zhong Shen

Frontiers in Oncology

doi 10.3389/fonc.2025.1590128

Original Research

Accepted on 19 May 2025

Evaluating the Multitargeted Potency of Pixuvri against Cell Cycle Regulation Proteins in Cervical Cancer

in Cancer Molecular Targets and Therapeutics

Mohammed Ali Alshehri
Hadil Alahdal
Akram Ahmed Aloqbi
Afnan Shakoori
Ghadir Sindi
Rehab M Bagadood
Nida Alsaffar
Mohammad Ahmad Alobaidy
Noof Abdulrahman Alrabiah
Md Khursheed

Frontiers in Oncology

doi 10.3389/fonc.2025.1598883

108 views

Original Research

Published on 19 May 2025

Preclinical NCI-MPACT: prospective modeling of the mutation-based NCI-MPACT clinical trial therapeutic strategy in patient-derived xenograft models

in Cancer Molecular Targets and Therapeutics

Yvonne A. Evrard
Sergio Y. Alcoser
Michael Mullendore
Li Chen
Chih-Jian Lih
Vishnuprabha Rahul Kannan
Vivekananda Datta
Lindsay Dutko
Shahanawaz Jiwani
Lawrence V. Rubinstein

Frontiers in Oncology

doi 10.3389/fonc.2025.1571635

449 views

Original Research

Published on 16 May 2025

A trispecific antibody targeting EGFR/cMET/VEGF-A demonstrates multiple mechanisms of action to inhibit wild-type and mutant NSCLC animal models

in Cancer Molecular Targets and Therapeutics

Ying Jin
Ping Sun
Peng Chen
Yuqiang Xu
Guangmao Mu
Zhengxia Zha
Simin Wu
Meixia Fu
Hao Jiang
Sheng Huang

Frontiers in Oncology

doi 10.3389/fonc.2025.1533059

556 views

Correction

Accepted on 15 May 2025

Corrigendum: MiR-21 and let-7 cooperation in the regulation of lung cancer

in Cancer Molecular Targets and Therapeutics

Jinquan Bai
Zhenzhou Shi
Shuting Wang
Hong Pan
Tong Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1602462

Perspective

Published on 15 May 2025

Bringing value to cancer research

in Cancer Molecular Targets and Therapeutics

Casey J. Allen
Horn M. Danea
Fabrice Smieliauskas
Stephen Edge
Rachel A. Greenup

Frontiers in Oncology

doi 10.3389/fonc.2025.1580575

299 views

Review

Published on 15 May 2025

Circulating tumor DNA laboratory processes and clinical applications in nasopharyngeal carcinoma

in Cancer Molecular Targets and Therapeutics

Ziman Wu
Haiyan Yang
Xinying Li
Xiang Ji
Chan Mo
Zhou Zheng
Yafei Xu
Dan Xiong

Frontiers in Oncology

doi 10.3389/fonc.2025.1520733

307 views

Review

Published on 14 May 2025

Role of exosomes in castration-resistant prostate cancer

in Cancer Molecular Targets and Therapeutics

Yuan Cao
Jianjun Wang
Huiwen Luo
Yaodong Wang
Xianfu Cai
Tiansheng Zhang
Yougang Liao
Decai Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1498733

406 views

Original Research

Accepted on 13 May 2025

Metabolic profiling of glioblastoma and identification of G0S2 as a metabolic target

in Cancer Molecular Targets and Therapeutics

Jianlei Kang
Yujie Xu
Qitai Zhao
Ying Wang
Zhenyan He
Xin Xu

Frontiers in Oncology

doi 10.3389/fonc.2025.1572040

108 views

Original Research

Published on 13 May 2025

Pan-cancer analysis reveals TRA16 as a master regulator of human carcinogenesis

in Cancer Molecular Targets and Therapeutics

Yanyan Zhu
Yike Gao
Xiaoqing Huang
Bowang Chen
Xinyi Wang
Ying Wu
Jian Sun
Xiaoyun Huang

Frontiers in Oncology

doi 10.3389/fonc.2025.1543419

625 views

Review

Published on 13 May 2025

Exploring two tumor treatment strategies: effectiveness of ribosome inactivating proteins and mesenchymal stem cells/MSC derived extracellular vesicles in cancer treatment

in Cancer Molecular Targets and Therapeutics

Maryamosadat Mavaei
Simin Farokhi
Mohammad Hasan Yousefi
Arshia Fakouri
Alireza Shadab
Mohammad Hossein Abdolmohammadi
Faranak Fallahian
Hamed Afkhami

Frontiers in Oncology

doi 10.3389/fonc.2025.1533065

604 views

Original Research

Accepted on 12 May 2025

Comprehensive pan-cancer analysis and experimental validation reveal FCHSD1 as a potential biomarker for diagnosis, immune infiltration, and prognosis

in Cancer Molecular Targets and Therapeutics

Ming Liu
Guixin Ding
Gonglin Tang
Shangjing Liu
Qiancheng Mao
Xidong Wang
Qingsong Zou
Jitao Wu

Frontiers in Oncology

doi 10.3389/fonc.2025.1547067

170 views