Frontiers in Oncology | Pediatric Oncology

Original Research

Accepted on 11 Aug 2025

Endotheliopathy Syndromes, TA-TMA and SOS, are Risk Factors for Morbidity and Mortality in Critically Ill Pediatric Hematopoietic Cell Transplant Recipients

in Pediatric Oncology

Shivani Goel
Erin Frost
Keiko Tarquino
Pradip P Kamat
Taylor Fitch
Elizabeth Stenger
Katie Liu
Muna Qayed
Zhulin He
Adrianna Westbrook

Frontiers in Oncology

doi 10.3389/fonc.2025.1642939

Case Report

Published on 11 Aug 2025

Case Report: Uncommon presentation of Ewing sarcoma complicated by hemophagocytic lymphohistiocytosis: a diagnostic dilemma and therapeutic challenge

in Pediatric Oncology

Zhuan Zou
Bin Chen
Fajuan Tang
Xihong Li
Chengshuang Huang

Frontiers in Oncology

doi 10.3389/fonc.2025.1613906

238 views

Case Report

Published on 11 Aug 2025

Pediatric small intestine cavernous lymphangioma detected via wireless capsule endoscopy: a rare case report

in Pediatric Oncology

Xiaoyu Yang
Junwen Guan
Yi Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1594332

224 views

Original Research

Published on 08 Aug 2025

Prevalence and prognostic impact of BRAF V600E mutation and CDKN2A deletion in pediatric high-grade glioma

in Pediatric Oncology

Soha Karim
Amal Mosaab
Hala Taha
Iman Naguib
Amal Refaat
Eslam Maher
Mohamed Saad Zaghloul
Mohamed El-Beltagy
Hanafy Hafez
Mohamed Kamal

Frontiers in Oncology

doi 10.3389/fonc.2025.1537268

511 views

Original Research

Accepted on 07 Aug 2025

Expression of aberrant markers in monitoring of measurable residual disease in B-cell precursor acute lymphoblastic leukemia patients during remission-inducing therapy phase

in Pediatric Oncology

Łukasz Słota
Łukasz Sędek
Monika Lejman
Bartosz Perkowski
Aleksandra Lasia
Joanna Bulsa
Wojciech Mlynarski
Jerzy Kowalczyk
Tomasz Szczepański

Frontiers in Oncology

doi 10.3389/fonc.2025.1641088

103 views

Case Report

Published on 07 Aug 2025

Case Report: Application of ex-vivo drug sensitivity testing to identify personalized treatment options for an adolescent with diffuse midline glioma

in Pediatric Oncology

Philip K. Tan
Timothy J. Martins
Pamela S. Becker
Robert J. Wechsler-Reya
John Ross Crawford

Frontiers in Oncology

doi 10.3389/fonc.2025.1606575

689 views

Systematic Review

Published on 06 Aug 2025

Meta-analysis of mortality factors after COVID-19 infection in pediatric oncology patients

in Pediatric Oncology

Qingchen Liu
Xia Wang
Xueqin Zhou

Frontiers in Oncology

doi 10.3389/fonc.2025.1594617

376 views

Case Report

Accepted on 04 Aug 2025

Cardiac tamponade as a rare presentation of Hodgkin's lymphoma: a case report

in Pediatric Oncology

Piotr Limanówka
Matylda Kujawińska
Anna Kaput
Aleksandra Spyra
Michał Dobrakowski
Tomasz Szczepański
Aneta Pobudejska-Pieniążek

Frontiers in Oncology

doi 10.3389/fonc.2025.1653256

Original Research

Published on 01 Aug 2025

Arginine methylation regulates Ewing sarcoma cell viability in a EWSR1::FLI1 dependent manner and provides a therapeutic opportunity

in Pediatric Oncology

Ciara M. Ward
Charles Brockwell
Gavin S. McNee
Emily Orton
Emily N. P. Prowse
Susanne A. Gatz
Clare C. Davies

Frontiers in Oncology

doi 10.3389/fonc.2025.1538208

714 views

Case Report

Accepted on 31 Jul 2025

Case Report: Relapsed alveolar rhabdomyosarcoma treated with abemaciclib, temozolomide, and irinotecan in the JPCS study

in Pediatric Oncology

Antonio Juan Ribelles
Nuria Benavent
Daniel Sanchez Mateos
Celine Pitou
Yanhong Zhou
Molly C. Hardebeck
Holly Knoderer
Adela Cañete

Frontiers in Oncology

doi 10.3389/fonc.2025.1637177

745 views

Review

Accepted on 31 Jul 2025

Treating and Triggering Hyperinflammation: Tackling Hemophagocytic Lymphohistiocytosis (HLH) and HLH-like syndromes in the Pediatric Cell Therapy and Critical Care Setting

in Pediatric Oncology

Holly Wobma
Lauren A. Henderson
Christine Noel Duncan
Susan E. Prockop
Adrienne G. Randolph
Barbara A. Degar
Leslie E. Lehmann
Susanne H.C. Baumeister

Frontiers in Oncology

doi 10.3389/fonc.2025.1631557

166 views

Original Research

Published on 30 Jul 2025

Molecular subtypes, prognostic factors, and treatment optimization in pediatric medulloblastoma: a real-world study from China

in Pediatric Oncology

Jingjing Liu
Yanling Sun
Huming Li
Shuxu Du
Jin Zhang
Zhen Zhang
Liming Sun
Wanshui Wu

Frontiers in Oncology

doi 10.3389/fonc.2025.1597123

493 views

Original Research

Accepted on 29 Jul 2025

Retrospective analysis of the efficacy and safety of anlotinib plus sintilimab (anti-PD-1) as maintenance therapy in advanced pediatric solid tumors

in Pediatric Oncology

Rui Zhao
Luyang Chang
Cheng Yi Zhang
Rongheng He
Xudong Wei

Frontiers in Oncology

doi 10.3389/fonc.2025.1518987

108 views

Brief Research Report

Accepted on 29 Jul 2025

New sepsis-associated morbidity and mortality in pediatric oncology patients: a secondary analysis of the TOPICC dataset

in Pediatric Oncology

Alicia M Alcamo
Robert B Lindell
Sydney A Sheetz
Steven D Ham
Andrew Strayer
Scott L Weiss
Akira Nishisaki
Neethi P Pinto
Alexis A Topjian
Julie C Fitzgerald

Frontiers in Oncology

doi 10.3389/fonc.2025.1638516

122 views

Original Research

Published on 28 Jul 2025

Impact of standardized immunophenotyping and MRD monitoring on early mortality reduction in childhood leukemia: a step towards addressing healthcare disparities in vulnerable populations from Southern Mexico

in Pediatric Oncology

Laura Alfaro-Hernández
Dalia Ramírez-Ramírez
Rubí Romo-Rodríguez
Karen Ayala-Contreras
Ángeles del Campo-Martínez
Enrique López-Aguilar
Janet Flores Lujano
Aldo Allende-López
Erika Alarcón-Ruiz
Ma Del Rocio Banos-Lara

Frontiers in Oncology

doi 10.3389/fonc.2025.1614445

773 views

Original Research

Published on 25 Jul 2025

Predictive model based on blood cell analysis and coagulation function indicators for neuroblastic tumors staging diagnosis

in Pediatric Oncology

Yanzi Zhang
Lihong Zhang
Mengmeng Chen
Qin Dong
Chong Hu
Juan Wang
Jiao Meng
Xin Lv

Frontiers in Oncology

doi 10.3389/fonc.2025.1575863

601 views