Frontiers in Oncology | Pharmacology of Anti-Cancer Drugs

Original Research

Published on 12 Jun 2025

Synergistic effects of 5-fluorouracil in combination with salinomycin promoted ferroptosis via inhibiting SLC7A11/GPX4 in colorectal cancer

in Pharmacology of Anti-Cancer Drugs

Can Wang
Junyang Wang
Fei Xing
Ning Liu
Xudong Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1558290

218 views

Clinical Trial

Published on 10 Jun 2025

Clinical outcomes of DNA-damaging agents and DNA damage response inhibitors combinations in cancer: a data-driven review

in Pharmacology of Anti-Cancer Drugs

Rick Fontenot
Neha Biyani
Kishor Bhatia
Reggie Ewesuedo
Marc Chamberlain
Panna Sharma

Frontiers in Oncology

doi 10.3389/fonc.2025.1577468

520 views

Original Research

Published on 06 Jun 2025

Interrogation of macrophage-related prognostic signatures reveals a potential immune-mediated therapy strategy by histone deacetylase inhibition in glioma

in Pharmacology of Anti-Cancer Drugs

Xisen Wang
Xuya Wang
Lei Chen
Haozhe Ding
Jikang Fan
Jianshen Liang
Yu Zhang
Yiming Li
Yiming Zhang
Shengping Yu

Frontiers in Oncology

doi 10.3389/fonc.2025.1554845

845 views

Original Research

Accepted on 30 May 2025

The Anti-Inflammatory Effects of Oridonin in Resisting Esophageal Cancer

in Pharmacology of Anti-Cancer Drugs

Mengfan Peng
Xiaofang Zhang
Lei Yang
Baosong Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1585057

123 views

Original Research

Published on 29 May 2025

A study on the effectiveness and safety of interventional embolization using drug-loaded microspheres in combination with sorafenib and envafolimab for intermediate and advanced renal cell carcinoma

in Pharmacology of Anti-Cancer Drugs

Cheng Chen
Yanfeng Shen
Yanhong Ma
Yingying Zhang
Shuyan Zhang
Na Su
Hefei Guo
Yapeng Guo
Xuehui Zhang
Xianming Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1558410

388 views

Correction

Published on 29 May 2025

Corrigendum: LCT-3d induces oxidative stress-mediated apoptosis by upregulating death receptor 5 in gastric cancer cells

in Pharmacology of Anti-Cancer Drugs

Menglin Wang
Xinxin Wu
Lu Yu
Zi-yun Hu
Xiaobo Li
Xia Meng
Chun-tao Lv
Gi-Young Kim
Yung Hyun Choi
Zhenya Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1590809

256 views

Original Research

Published on 29 May 2025

Molecular targets and mechanisms of cortex mori for lung cancer treatment: a network pharmacology study, molecular docking and in vitro and in vivo experimental validation

in Pharmacology of Anti-Cancer Drugs

Ying-Ying Shao
Qiu-Hong Yang
Shu-Fen He
Han-Bin Zhang
Wei-Chao Han
Bao-Cheng Xie
Rui-Rong He
Wen-Xin Hong

Frontiers in Oncology

doi 10.3389/fonc.2025.1587856

568 views

Original Research

Published on 29 May 2025

Development of CSOARG: a single-cell and multi-omics-based machine learning model for ovarian cancer prognosis and drug response prediction

in Pharmacology of Anti-Cancer Drugs

Junyu Chen
Bin Guan
Jihong Zhang
Xin Li
Jingyi Fang
Wencai Guan
Qi Lu
Guoxiong Xu

Frontiers in Oncology

doi 10.3389/fonc.2025.1592426

400 views

Brief Research Report

Published on 27 May 2025

Severe immunotherapy-related thrombocytopenia in metastatic bone cancer: a multicenter retrospective case series highlighting early recognition and management

in Pharmacology of Anti-Cancer Drugs

Qian Gao
Zhaonong Yao
Yuhong Yao
Yunxia Liu
Jianshui Mao
Binghao Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1574379

394 views

Review

Accepted on 23 May 2025

Aberrant Angiogenic Signaling in HCC: Therapeutic Targeting and Drug Resistance

in Pharmacology of Anti-Cancer Drugs

Hongtao Zhang
Zhaoming Yang
Zhengwu Jiang
Zhijian Zhao
Xun Chen
Jian Wan
Yukun Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1595195

143 views

Original Research

Published on 23 May 2025

Combination therapy of TKIs and ICIs for the treatment of anaplastic thyroid carcinoma

in Pharmacology of Anti-Cancer Drugs

Xi Zhang
Hongzhi Lu
Yuanshi Lv
Hong Gao
Hui Jin

Frontiers in Oncology

doi 10.3389/fonc.2025.1564865

433 views

Editorial

Published on 22 May 2025

Editorial: EGFR-TKIs for lung cancer treatment: development, application, and side effects

in Pharmacology of Anti-Cancer Drugs

Qinglin Shen
Hexiao Tang
Shengxi Chen

Frontiers in Oncology

doi 10.3389/fonc.2025.1617788

576 views

Original Research

Published on 21 May 2025

Antiproliferative and pro-apoptotic effects of Pseudevernia furfuracea (L.) Zopf extract and its active component physodic acid via oxidative stress and DNA damage in breast cancer cells

in Pharmacology of Anti-Cancer Drugs

Dominika Sebova
Simona Zilakova
Viktoria Medvecova
Michal Goga
Richard Frenak
Annamaria Bardelcikova
Andrej Mirossay
Ladislav Mirossay
Jan Mojzis
Martin Kello

Frontiers in Oncology

doi 10.3389/fonc.2025.1557884

757 views

Original Research

Published on 19 May 2025

Iodine-131 induces ferroptosis and synergizes with sulfasalazine in differentiated thyroid cancer cells via suppressing SLC7A11

in Pharmacology of Anti-Cancer Drugs

Li Ling
Jinhe Zhang
Xiao Zhang
Peiqi Wang
Mingjun Ma
Bingling Yin

Frontiers in Oncology

doi 10.3389/fonc.2025.1580828

900 views

Original Research

Published on 16 May 2025

Cyclophosphamide for anticancer therapy-induced interstitial lung disease in the modern era: a retrospective cohort study

in Pharmacology of Anti-Cancer Drugs

Honami Katahara
Kaede Baba
Hiromichi Nakajima
Chikako Funasaka
Chihiro Kondoh
Yoichi Naito
Hibiki Udagawa
Kohei Shitara
Tomoaki Sasaki
Toshikatsu Kawasaki

Frontiers in Oncology

doi 10.3389/fonc.2025.1567317

868 views

Review

Published on 15 May 2025

Application of bifidobacterium in tumor therapy

in Pharmacology of Anti-Cancer Drugs

Yinwu Kong
Han Bai
Feifei Deng
Yaomin Zhao
Qianyan Li
Li Chang

Frontiers in Oncology

doi 10.3389/fonc.2025.1551924

906 views