Frontiers in Oncology | Thoracic Oncology

Original Research

Published on 20 Nov 2025

Deciphering the let-7c-5p/RRM2 axis in lung adenocarcinoma: expression, prognosis, and immune landscape implications

in Thoracic Oncology

Jinlong Liu
Jinying Wu
Yu Han
Lele Li
Xingbo Bian
Xialin Sun
Xuefeng Bian
Xin Sun

Frontiers in Oncology

doi 10.3389/fonc.2025.1628429

504 views

Original Research

Published on 19 Nov 2025

Prognostic significance of the lymphocyte-to-high-density lipoprotein ratio in long-term efficacy of combined immunotherapy for advanced non-small cell lung cancer

in Thoracic Oncology

Gaolei Ma
Lijie Ma
Yuan Zhang
Yuanyuan Chen
Yingnan Zhang
Wenwen Guo
Zhiyuan Yao
Guijuan Ji

Frontiers in Oncology

doi 10.3389/fonc.2025.1712779

819 views

Case Report

Published on 19 Nov 2025

Case Report: A case of necrotizing sarcoid granulomatosis mimicking metastatic tumor

in Thoracic Oncology

Lingjun Dong
Linhai Fu
Desheng Wei
Guangmao Yu

Frontiers in Oncology

doi 10.3389/fonc.2025.1703599

453 views

Original Research

Published on 18 Nov 2025

CD20+ and CD204+ exhibit distinct prognostic associations in thymic epithelial tumors

in Thoracic Oncology

Qinyang Chen
Jian Zhang
Jianwei Feng
Chaowen Chen
Chuan Su
Wenxiu Yao

Frontiers in Oncology

doi 10.3389/fonc.2025.1710544

669 views

Original Research

Published on 14 Nov 2025

CD302 regulates the malignant phenotypes of lung adenocarcinoma as a tumor suppressor gene

in Thoracic Oncology

Kai Wang
Yao Wang
Tao Lu
Manjun Gao
Yongxiang Song
Cheng Chen
Xixian Ke

Frontiers in Oncology

doi 10.3389/fonc.2025.1601706

732 views

Mini Review

Published on 13 Nov 2025

AI-based prediction of pathological risk factors in lung adenocarcinoma from CT imaging: bridging innovation and clinical practice

in Thoracic Oncology

Yu Huang
Bowen Zhao
Ruiyang Yan
Chi Zhang
Zuhan Geng
Peiyuan Mei
Kuo Li
Yongde Liao

Frontiers in Oncology

doi 10.3389/fonc.2025.1687360

796 views

Original Research

Published on 10 Nov 2025

18F-FAPI-04 PET/CT in the evaluation of ground-glass nodules less than 3 cm in diameter comparing to 18F-FDG PET/CT

in Thoracic Oncology

Zhehao Lyu
Jianing Liu
Wei Han
Shibo Guo
Chunyu Duan
Lili Liu
Hongyue Zhao
Yexin Su
Haibo Wang
Qi Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1605678

924 views

Correction

Published on 07 Nov 2025

Correction: Case report: A case report and literature review on the efficacy of high-dose aumolertinib combined intrathecal pemetrexed by Ommaya reservoir for EGFR-mutated NSCLC with leptomeningeal metastasis as the initial symptoms

in Thoracic Oncology

Maoxi Zhong
Li Zhou
Jing Guo
Chuan Chen
Yi Liu
Xiaoping Huang
Wei Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1720422

416 views

Original Research

Published on 07 Nov 2025

Predicting immunotherapy response in stage III-IV non-small cell lung cancer using integrated radiomics and clinical features

in Thoracic Oncology

Na Geng
Zhijun Li
Langlang Deng
Yuxiang Li
Haitao Ma

Frontiers in Oncology

doi 10.3389/fonc.2025.1669469

863 views

Case Report

Published on 06 Nov 2025

Case Report: Pitfalls in anatomic pathology and clinical oncology: a case of misdiagnosed pulmonary Ewing sarcoma as SCLC

in Thoracic Oncology

Nagham S. El Waary
Angelo A. Chami
Jawad K. Zrein
Doha A. Houcheimy
Ryan T. Akl
Siham D. Fleifel
Francois G. Kamar

Frontiers in Oncology

doi 10.3389/fonc.2025.1635424

890 views

Original Research

Published on 06 Nov 2025

Analysis of short-term clinical efficacy and immune function changes of advanced non-small cell lung cancer after radiotherapy or chemotherapy under CT-guided 125I seed implantation

in Thoracic Oncology

Songbai Chen
Yunfeng Kou
Yuting Yuan
Guangsheng Zhao
Jun Zhou
Ruoyu Wang
Zhe Wang
Chuang Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1667205

584 views

Original Research

Published on 04 Nov 2025

MiR-4664-3p as a potential diagnostic, prognostic, and immunotherapeutic biomarker in NSCLC: modulation of tumor progression through CD8 + T cell regulation

in Thoracic Oncology

Chun Yi
Hao Zhang
Qianqian Guo
Linzhu Lu
Cong Gao
Yunlong Zhao
Yan Su
Jing Lu

Frontiers in Oncology

doi 10.3389/fonc.2025.1642999

812 views

Case Report

Accepted on 03 Nov 2025

CASE REPORT: MUCOEPIDERMOID CARCINOMA OF THE LUNG, A CHALLENGING DIAGNOSIS OF AN UNUSUAL CASE

in Thoracic Oncology

María C. Garijo Martínez
Alejandro Olivares Hernández
Lorena Bellido Hernández
Fernando L Begliardo
Daniel Morchón Araujo
Jonnathan Roldán Ruiz
Juan Carlos Redondo-González
Luis Posado Domínguez
Emilio Fonseca Sánchez
EDEL DEL BARCO MORILLO

Frontiers in Oncology

168 views

Original Research

Published on 31 Oct 2025

To predict the spread through air spaces in lung adenocarcinoma using radiomic features from different regions of part-solid nodules: a multicenter study

in Thoracic Oncology

Shiyu Cui
Hongzheng Song
Fanxia Lin
Xiaomeng Han
Bo Wang
Liang Zhang
Feng Hou
Enhao Kang
Jizheng Lin
Henan Lou

Frontiers in Oncology

doi 10.3389/fonc.2025.1700843

811 views

Original Research

Published on 31 Oct 2025

Preoperative plasma fibrinogen combined with the platelet-to-lymphocyte ratio (F-PLR) serves as a prognostic indicator in patients with non-small cell lung cancer

in Thoracic Oncology

Hongzhen Zhao
Xiaopeng Zhang
Dahu Ren
Shicheng Liu
Yuedong Wang
Wenbo Wu
Kun Zhang
Yajing Niu
Guochen Duan

Frontiers in Oncology

doi 10.3389/fonc.2025.1587443

640 views

Original Research

Published on 30 Oct 2025

Predicting EGFR gene mutation in lung adenocarcinoma using spectral CT combined with AI parameters: a diagnostic accuracy study

in Thoracic Oncology

Lilan She
Min Xie
Guolin Xu
Xiangmei Zhan
Meilan Huang
Yunjing Xue

Frontiers in Oncology

doi 10.3389/fonc.2025.1611759

957 views

Original Research

Published on 29 Oct 2025

Fusion of CT radiomics and autoantibody biomarkers for enhanced prediction of lung cancer diagnosis: a comprehensive study

in Thoracic Oncology

Xianwu Xia
Jinshuo Liu
Yiman Du
Xiaowen Ma
Guoming Zhou
Jianjun Yuan
Qianjin Hua
Lingling Wang
Haitao Jiang
Caidi He

Frontiers in Oncology

doi 10.3389/fonc.2025.1591156

1,051 views

Original Research

Published on 29 Oct 2025

Development and validation of machine learning models for predicting STAS in stage I lung adenocarcinoma with part-solid and solid nodules: a two-center study

in Thoracic Oncology

Qing-Lin Ren
Liu Lin
Kai Chu
Xin-Rong Xu
Hui-Jun Wang
Jun Wu
Jin-Zhi You
Jun-Xi Hu
Xiao-Lin Wang
Yu-Sheng Shu

Frontiers in Oncology

doi 10.3389/fonc.2025.1682633

823 views

Case Report

Published on 28 Oct 2025

Long-term survival following multimodal therapy for lung cancer with hepatic metastasis: a case report

in Thoracic Oncology

Zhao Junjun
Zhang Jiandong
Dong Lingjun
Yu Guangmao
Zhang Chu

Frontiers in Oncology

doi 10.3389/fonc.2025.1663079

1,205 views

Case Report

Published on 27 Oct 2025

Case Report: Evolution and targeted therapy of an EGFR-mutant large-cell neuroendocrine carcinoma

in Thoracic Oncology

Li Jiang
Xiaowen Yao
Xiuyu Cai
Pengfei Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1599765

1,240 views

Original Research

Published on 27 Oct 2025

Preoperative absolute neutrophil count: a potential indicator for prognosis in carcinoembryonic antigen normal stage I non-small cell lung cancer

in Thoracic Oncology

Bailin Wang
Long Liu
Meiqi Cui
Qianwen Ye
Panhua Li
Bing Yan

Frontiers in Oncology

doi 10.3389/fonc.2025.1632597

597 views

Brief Research Report

Published on 27 Oct 2025

Impact of prior immunotherapy on paclitaxel/bevacizumab in advanced non-squamous non-small cell lung cancer

in Thoracic Oncology

Agathe Peyret
Clémentine Le Berrurier
Luc Heraudet
Tara Delon
Maéva Zysman
Mathieu Larroquette
Laura Leroy
Sophie Cousin
Charlotte Domblides

Frontiers in Oncology

doi 10.3389/fonc.2025.1675386

1,286 views

Original Research

Published on 27 Oct 2025

Conformal sublobar electroresection with volume optimization achieves greater parenchymal preservation than stapler in wedge resection: a volumetric analysis

in Thoracic Oncology

Xining Zhang
JingWei Liu
ShiJie Zhang
Jian Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1657405

672 views

Review

Published on 27 Oct 2025

A comparison of clinical guidelines, treatment characteristics and outcomes in small cell lung cancer between East Asia and Europe/North America

in Thoracic Oncology

Chi-Lu Chiang
Ross Andrew Soo
Tony Mok
Pei Jye Voon
Lucksamon Thamlikitkul
Ying Cheng
Hidehito Horinouchi
Byong Chul Cho
Krista Lin Xu
Myung-Ju Ahn

Frontiers in Oncology

doi 10.3389/fonc.2025.1646608

2,004 views

1,909 articles

articles

Deciphering the let-7c-5p/RRM2 axis in lung adenocarcinoma: expression, prognosis, and immune landscape implications

Prognostic significance of the lymphocyte-to-high-density lipoprotein ratio in long-term efficacy of combined immunotherapy for advanced non-small cell lung cancer

Case Report: A case of necrotizing sarcoid granulomatosis mimicking metastatic tumor

CD20+ and CD204+ exhibit distinct prognostic associations in thymic epithelial tumors

CD302 regulates the malignant phenotypes of lung adenocarcinoma as a tumor suppressor gene

AI-based prediction of pathological risk factors in lung adenocarcinoma from CT imaging: bridging innovation and clinical practice

18F-FAPI-04 PET/CT in the evaluation of ground-glass nodules less than 3 cm in diameter comparing to 18F-FDG PET/CT

Correction: Case report: A case report and literature review on the efficacy of high-dose aumolertinib combined intrathecal pemetrexed by Ommaya reservoir for EGFR-mutated NSCLC with leptomeningeal metastasis as the initial symptoms

Predicting immunotherapy response in stage III-IV non-small cell lung cancer using integrated radiomics and clinical features

Case Report: Pitfalls in anatomic pathology and clinical oncology: a case of misdiagnosed pulmonary Ewing sarcoma as SCLC

Analysis of short-term clinical efficacy and immune function changes of advanced non-small cell lung cancer after radiotherapy or chemotherapy under CT-guided 125I seed implantation

MiR-4664-3p as a potential diagnostic, prognostic, and immunotherapeutic biomarker in NSCLC: modulation of tumor progression through CD8 + T cell regulation

CASE REPORT: MUCOEPIDERMOID CARCINOMA OF THE LUNG, A CHALLENGING DIAGNOSIS OF AN UNUSUAL CASE

To predict the spread through air spaces in lung adenocarcinoma using radiomic features from different regions of part-solid nodules: a multicenter study

Preoperative plasma fibrinogen combined with the platelet-to-lymphocyte ratio (F-PLR) serves as a prognostic indicator in patients with non-small cell lung cancer

Predicting EGFR gene mutation in lung adenocarcinoma using spectral CT combined with AI parameters: a diagnostic accuracy study

Fusion of CT radiomics and autoantibody biomarkers for enhanced prediction of lung cancer diagnosis: a comprehensive study

Development and validation of machine learning models for predicting STAS in stage I lung adenocarcinoma with part-solid and solid nodules: a two-center study

Long-term survival following multimodal therapy for lung cancer with hepatic metastasis: a case report

Case Report: Evolution and targeted therapy of an EGFR-mutant large-cell neuroendocrine carcinoma

Preoperative absolute neutrophil count: a potential indicator for prognosis in carcinoembryonic antigen normal stage I non-small cell lung cancer

Impact of prior immunotherapy on paclitaxel/bevacizumab in advanced non-squamous non-small cell lung cancer

Conformal sublobar electroresection with volume optimization achieves greater parenchymal preservation than stapler in wedge resection: a volumetric analysis

A comparison of clinical guidelines, treatment characteristics and outcomes in small cell lung cancer between East Asia and Europe/North America