Frontiers in Pharmacology | Cardiovascular and Smooth Muscle Pharmacology

Original Research

Accepted on 20 Nov 2025

Preventive effect of small molecule active substances on septic cardiomyopathy after abdominal trauma: A systematic review and meta-analysis

in Cardiovascular and Smooth Muscle Pharmacology

Gen Ouyang
Neng Wang
Yujuan Liu
Chuang Yang
Peng Zeng
Tao Gong
Lu Tao
Ying Zheng
Guiying Ye
Hong Li

Frontiers in Pharmacology

Original Research

Accepted on 20 Nov 2025

Gallic acid attenuates diabetic cardiomyopathy by inhibiting ferroptosis and protecting mitochondria via the TSPO/FTMT pathway

in Cardiovascular and Smooth Muscle Pharmacology

Chenchao Zou
Huaihan Xu
Fajia Hu
Yuxian Yu
Lanxiang Liu
Xiuqi Wang
Zheyu Zhang
Huaxi Zou
Jichun Liu
Songqing Lai

Frontiers in Pharmacology

Original Research

Accepted on 19 Nov 2025

The complications of cyclosporine A in pediatric use and its effectiveness in treating pediatric congenital heart diseases-a meta analysis in combined with a retrospective clinical study

in Cardiovascular and Smooth Muscle Pharmacology

Lincai Ye
Yiting Xue
Siqi She
Sijuan Sun
Junxian Chen
Yanhui Huang

Frontiers in Pharmacology

Original Research

Published on 19 Nov 2025

The potential mechanism of celastrol attenuating atherosclerosis by promoting macrophage autophagy via AMPK/ULK1 pathway

in Cardiovascular and Smooth Muscle Pharmacology

Jiao Li
Yanrong Zhao
Yanfang Qi
Yafang Chen
Yue Liu
Linlin Fang
Zhenying Zhou
Liping Wei
Qi Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1700663

267 views

Original Research

Accepted on 18 Nov 2025

Ensemble Learning Approach with Explainable AI for Improved Heart Disease Prediction

in Cardiovascular and Smooth Muscle Pharmacology

Ayomide Adekoya
Faisal Saeed
Wad Ghaban
Sultan Noman Qasem

Frontiers in Pharmacology

Original Research

Accepted on 18 Nov 2025

Impact of Different Doses of Rivaroxaban on Clinical Outcomes in Elderly Patients with Non-Valvular Atrial Fibrillation: A Real-World Study

in Cardiovascular and Smooth Muscle Pharmacology

Juan Yu
Zufeng Zhang
Qingru Yuan
Haobing Hu
Huimin Li
Meifang Huang
Youlin Mao

Frontiers in Pharmacology

Review

Published on 17 Nov 2025

Endoplasmic reticulum oxidoreductin 1α as a potential therapeutic target in diseases: from oxidative protein folding to pathophysiological mechanisms

in Cardiovascular and Smooth Muscle Pharmacology

Fang He
Xiaoyue Ge
Xiaohui Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1709284

222 views

Original Research

Published on 17 Nov 2025

Terminal complement inhibition in atypical haemolytic uremic syndrome: a single-centre experience

in Cardiovascular and Smooth Muscle Pharmacology

Valentin D. Mocanu
Bogdan M. Sorohan
Elena G. Micu
Sonia Bălănică
Bogdan Obrişcă
Roxana A. Jurubiță
Camelia A. Achim
Adrian C. Lungu
Cristina S. Căpuşă
Gabriel Mircescu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1683188

804 views

Original Research

Accepted on 14 Nov 2025

Gut Microbiota-Dependent Anti-Inflammatory Mechanisms of Berberine in Ameliorating Hypertension: Role of SCFAs, LPS Reduction, and STAT3 Signaling

in Cardiovascular and Smooth Muscle Pharmacology

Wang Shanshan
Yaqian Hu
Xin Li
Yanhua Ou
Jinling Chen
Chen Yuhan
Jingyi Chen
Kunran Bai
Fangwen Xu
Xingyi Wang

Frontiers in Pharmacology

268 views

General Commentary

Accepted on 12 Nov 2025

Commentary: Hyperoside alleviates myocardial ischemia-reperfusion injury in heart transplantation by promoting mitochondrial fusion via activating the Stat3-Tom70-Opa1 pathway

in Cardiovascular and Smooth Muscle Pharmacology

Qin Yang
Yingjie Liu
Xinzheng Tang

Frontiers in Pharmacology

101 views

Original Research

Accepted on 10 Nov 2025

Association between Ranolazine therapy and cognitive decline in elderly patients with ischemic heart disease

in Cardiovascular and Smooth Muscle Pharmacology

Giandomenico Severini
Giuseppe Armentaro
Velia Cassano
Valentino Condoleo
Carlo Alberto Pastura
Alberto Panza
Carlo Fuoco
Sofia Miceli
Teresa Vanessa Fiorentino
Maria Perticone

Frontiers in Pharmacology

Review

Accepted on 10 Nov 2025

Echocardiographic assessment and new advances of right ventricle function in rats with pulmonary hypertension

in Cardiovascular and Smooth Muscle Pharmacology

Weijie Wang
Ming Ren
Dianxiang Lu

Frontiers in Pharmacology

Review

Published on 10 Nov 2025

The unmet promise: a critical review of antioxidant strategies in myocardial ischemia-reperfusion injury and the path towards precision medicine

in Cardiovascular and Smooth Muscle Pharmacology

Hao Chen
Yutao Tang
Pan Ren
Wenbin Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1693441

640 views

Original Research

Published on 10 Nov 2025

A novel bioactive peptide-peptoid hybrid of alpha-calcitonin gene-related peptide protects against pressure-overload induced heart failure

in Cardiovascular and Smooth Muscle Pharmacology

Ambrish Kumar
Sarah Deloach
Lernix Williams
Donald J. DiPette
Jay D. Potts

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1692472

807 views

Case Report

Published on 07 Nov 2025

Rifampicin-induced challenges in managing endocrine hypertension and primary aldosteronism: a case report and literature review

in Cardiovascular and Smooth Muscle Pharmacology

Xiaoxiao Song
Minyue Jia
Hanxiao Yu
Zhichao Dong
Kai Cheok
Xin Pan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1678430

408 views

Original Research

Published on 31 Oct 2025

Agonizing GABABR suppresses GLP-1RA’s chronotropic effect and reduces post-myocardial infarction arrhythmogenesis

in Cardiovascular and Smooth Muscle Pharmacology

Run Qi
Zhang Jingjing
Gu Hongchang
Li Chenyu
Hu He
Li Juan
Zhao Yuqin
Wu Xiaolin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1616181

2,369 views