Frontiers in Pharmacology | Obstetric and Pediatric Pharmacology

Original Research

Published on 04 Dec 2025

Physiologically-based pharmacokinetic modeling and simulation for initial dose optimization of levetiracetam in pediatrics

in Obstetric and Pediatric Pharmacology

Julia Macente
Rodolfo Hernandes Bonan
Edilainy Rizzieri Caleffi-Marchesini
Leonardo Régis Leira Pereira
Priscila De Freitas Lima
Pieter Annaert
Karel Allegaert
Andrea Diniz

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1678960

330 views

Systematic Review

Published on 27 Nov 2025

The efficacy and safety of combining different Chinese patent medicines with conventional Western drugs in the treatment of pediatric allergic rhinitis: network meta-analysis

in Obstetric and Pediatric Pharmacology

Yue Ma
Wenrui Huang
Hang Wu
Chunbo Zhang
Zhiyue Xiao
Yuying Gao
Junying Xie
Jingyao Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1693357

496 views

Original Research

Published on 25 Nov 2025

Effect of preoperative intranasal dexmedetomidine versus placebo on intraoperative shivering in parturients undergoing cesarean section: a randomized controlled trial

in Obstetric and Pediatric Pharmacology

Guolin Xu
Zhuhong Tian
Yong Ding
Jingjing Ma
Rui Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1661683

294 views

Original Research

Accepted on 24 Nov 2025

Effects of Methylphenidate on Children with Attention Deficit Hyperactivity Disorder: A Study Using Clinical and Multimodal Approaches Including Go/No-Go Task and Functional Near-infrared Spectroscopy

in Obstetric and Pediatric Pharmacology

Fang Shen
Zhou Hui

Frontiers in Pharmacology

Original Research

Published on 24 Nov 2025

Effects of remimazolam on hemodynamics in children with congenital heart disease undergoing cardiac catheterization

in Obstetric and Pediatric Pharmacology

Hongyun Li
Zhaomeng Song
Xunwei Jiang
Wei Liu
Yan Jiang
Rong Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1714645

265 views

Original Research

Published on 21 Nov 2025

Medical cannabis utilization in children – a study based on a nationwide cohort

in Obstetric and Pediatric Pharmacology

Nir Treves
Noa Yakirevich-Amir
Karel Allegaert
John N. van den Anker
Elkana Kohn
Maya Berlin
Ariela Hazan
Elyad Davidson
Matitiahu Berkovitch
Omer Bonne

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1646560

435 views

Original Research

Accepted on 18 Nov 2025

Validation of diagnostic screening test for Pharmacogenomic targets for Thiopurine drugs in Indian Pediatric acute lymphoblastic leukemia patients

in Obstetric and Pediatric Pharmacology

GRATIAL THERES JOSEPH
Sandeep Kumar Swain
TEJAS SOMWANSHI
Aarishi Singh
Manpreeet Kaur
Raj Kamal
Himanshu Dhanda
Prashant Kumar
Upasana Kaushik
Baseer Noor

Frontiers in Pharmacology

119 views

Original Research

Accepted on 18 Nov 2025

Acceptability of minitablets in soft food. A randomised cross-over study in children

in Obstetric and Pediatric Pharmacology

Jennifer Claire Duncan
Rebecca Page
Janet Clark
Gabrielle Seddon
Joy Slater
Andrea Gill
Silothabo Dliso
Udeme Ohia
Nikolaos Skoutelis
Leonie Wagner

Frontiers in Pharmacology

102 views

Case Report

Published on 11 Nov 2025

Accidental cannabis intoxication in two young children: clinical presentation and toxicokinetics - a case series

in Obstetric and Pediatric Pharmacology

Alessia Cafaro
Federica Pigliasco
Sebastiano Barco
Ilaria Negro
Emanuela Piccotti
Luca Manfredini
Samir Mahameed
Roberto Bandettini
Carla Debbia
Francesca Mattioli

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1695194

796 views

Original Research

Published on 03 Nov 2025

Propranolol (1 mg/kg/day) with intralesional bleomycin versus propranolol monotherapy for infantile hemangioma: a randomized controlled trial

in Obstetric and Pediatric Pharmacology

Yanyan Guo
Xinxian Liu
Sicheng He
Bin Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1710517

617 views

Original Research

Published on 27 Oct 2025

Comparative study between calcium gluconate with diosmin, cabergoline, and cabergoline with diosmin in prevention of ovarian hyperstimulation syndrome in high-risk women undergoing intracytoplasmic sperm injection (ICSI) procedures

in Obstetric and Pediatric Pharmacology

Aya M. Abdallah
Amal K. Hussien
Sumaiah J. Alarfaj
Thanaa A. Elmasry
Marwa Kamal
Hatem Sarhan
Mohammed H. Mosbeh
Eman Mohamed Sadek

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1655866

658 views

Mini Review

Published on 20 Oct 2025

Pain and anesthesia — on fetal nervous system and brain development

in Obstetric and Pediatric Pharmacology

Mengjie Gao
Ganzhu Bao
Shuancheng Bai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1710759

1,037 views

Clinical Trial

Published on 13 Oct 2025

A randomized controlled study of remimazolam in preschool children undergoing adenotonsillectomy

in Obstetric and Pediatric Pharmacology

Yong Wu
Fenjun Wang
Kai Zhu
Li Ling
Wangping Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1678650

1,680 views

Original Research

Published on 08 Oct 2025

The effective sedative dose of remimazolam for BIS <60 during general anesthesia induction between elderly and non-elderly patients-A randomized controlled trial

in Obstetric and Pediatric Pharmacology

Jun-Li Zheng
Jie-Feng Sun
Qing Han
Si-Ren Shi
Jin Zhou
Wei-Long Wang
Xiao-Dong Huang
Zhen-Feng Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1692105

1,701 views

Case Report

Published on 02 Oct 2025

Severe hematologic toxicity after low-dose methotrexate in ectopic pregnancy: role of MTHFR polymorphism and drug interaction - a case report and literature review

in Obstetric and Pediatric Pharmacology

Xiaojie Huang
Fangjie He
Yanhong Deng
Shengying Shi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1671369

3,538 views
1 citation

Original Research

Published on 01 Oct 2025

Pharmacoeconomic evaluation of ICS-LABA therapy in pediatric asthma: a cost-effectiveness and cost-utility analysis

in Obstetric and Pediatric Pharmacology

Fan Dai
Jin Xu
Jing Xu
Wenjing Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1639444

2,592 views