Frontiers in Pharmacology | Renal Pharmacology

Original Research

Published on 08 Jul 2025

Luteolin delays the progression of IgA nephropathy by attenuating inflammation, oxidative stress and reducing extracellular matrix accumulation through activating the Nrf-2/HO-1 pathway

in Renal Pharmacology

Dong-Yu Liang
Shao-Hua Cong
Lin-Hui Li
Qing-Qing Yi
Li-Ping Tang
Li-Ou Cao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1530655

384 views

Review

Accepted on 07 Jul 2025

Inhibitory Effects of Herbal Monomers on Ferroptosis in Renal Fibrosis: A Review and Mechanistic Study

in Renal Pharmacology

Kaixiang Liu
Min Yu
Yangyang He
Ting Wang
Guisen Li
Li Wang
Xiang Zhong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1610573

Editorial

Accepted on 03 Jul 2025

Editorial: Acute Kidney Injury: From Pathology to Phytotherapy

in Renal Pharmacology

Ya-long Feng
Wan-Ying Ma
Yin-Xuan Jiang
Le Shui
Hua Chen
Xuezhong Gong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1649837

128 views

Review

Accepted on 30 Jun 2025

High-mobility group box 1 in acute kidney injury

in Renal Pharmacology

Xuan Li
Guilin Jing
Zhentao Guo
Zhaoan Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1618971

138 views

Original Research

Accepted on 30 Jun 2025

The effects of Shenkang suppository on kidney function and gut microbiota in nondialysis patients with chronic kidney disease stages 3-4: A randomized controlled trial

in Renal Pharmacology

Weiwei Zhang
Xin Zhang
Shuang Xu
Yousuf Abdulkarim Waheed
Yizhou Xu
Shulin Li
Dong Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1621208

114 views

Original Research

Accepted on 30 Jun 2025

Huangkui capsule combined with finerenone attenuate diabetic n ephropathy by regulating JAK2/STAT3 signaling pathway based on network pharmacology, molecular docking and experimental verification

in Renal Pharmacology

Xunake Liua
Chunjiang Zhanga
Yanjie Fua
JingJing Daia
Jiaying Lua
Gang Lua
Xiaoping Yanga

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1625286

114 views

Original Research

Accepted on 30 Jun 2025

Acridocarpus smeathmannii Root Extracts Inhibit Human Prostate and Bladder Smooth Muscle Contraction, Porcine Arterial Vasoconstriction, and Cytotoxicity of Prostate Stromal Cells

in Renal Pharmacology

OLUWAFEMI Ezekiel KALE
Sheng Hu
Claudia Huber
Felix Schierholz
Anna Ciotkowska
Alexander Tamalunas
Christian G. Stief
Wolfgang Eisenreich
Martin Hennenberg

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1621346

Review

Published on 27 Jun 2025

Critical role of LncRNA in sepsis-associated acute kidney injury

in Renal Pharmacology

Lingjian Jin
Jian Liao
Litong Jin
Chunyan Chen
Feng Yuan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1627253

250 views

Original Research

Published on 24 Jun 2025

Efficacy and safety of HSK21542 for pruritus management in hemodialysis patients: a multicenter, randomized, double-blind, placebo-controlled trial

in Renal Pharmacology

Ming-Ming Pan
Min Gao
Li Zhou
Yan Xu
Li Yao
Chao-Qing Wu
Chang-Lin Mei
Zhan-Zheng Zhao
Dong Sun
Tian-Jun Guan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1583515

379 views

Systematic Review

Published on 24 Jun 2025

Effectiveness and safety of Shengxuening for treatment of renal anemia: a comprehensive systematic review and meta-analysis

in Renal Pharmacology

Li Zheng
Xiaotong Gu
Ming Liu
Changhai Fu
Yan Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1510227

288 views

Original Research

Published on 20 Jun 2025

Integrating single-cell RNA-seq, bulk RNA-seq and network pharmacology reveals protective effect of salidroside in peritoneal dialysis-associated peritoneal fibrosis

in Renal Pharmacology

Shuting Li
Yue Ji
Silin Zhu
Mi Liu
Dan Luo
Qimei Luo
Min Mo
Haibo Long
Fenfen Peng
Zhanjun Jia

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1558366

623 views

Original Research

Published on 20 Jun 2025

The impact of early use of statin in sepsis patients with acute kidney injury: a study based on MIMIC-IV

in Renal Pharmacology

Xiaona Zhan
Haifeng Huang
Ling Ye
Shenglang Zhu
Jiehui Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1610450

659 views

Original Research

Published on 10 Jun 2025

Dimethyl malonate alleviates obstructive nephropathy by enhancing renal metabolism and inhibiting kidney oxidative stress and inflammation

in Renal Pharmacology

Wei Zhang
Changde Fu
Jinjin Lai
Jun Xin
Wenbin Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1530635

776 views

Original Research

Published on 09 Jun 2025

Homotherapy for heteropathy of chronic kidney disease and oligoasthenozoospermia through regulating SIRT1/NF-κB pathway by Shenqi pills

in Renal Pharmacology

Shuo Huang
Qihan Luo
Xinyue Li
Yiming Liu
Jiale Wei
Sichen Wang
Ping Qiu
Changyu Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1551423

1,156 views

Systematic Review

Published on 02 Jun 2025

Tetramethylpyrazine and renal ischemia-reperfusion injury: a systematic review and meta-analysis of preclinical studies

in Renal Pharmacology

Zhongmei Fu
Lianyan Jiang
Xiaojuan Su
Hua Wang
Mingquan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1559314

892 views

Original Research

Published on 30 May 2025

ATP/P2X7 receptor/NLRP3 pathway facilitates renal tubular epithelial-myofibroblast transdifferentiation and interstitial fibrosis in rats with unilateral ureteral obstruction

in Renal Pharmacology

Hui Tan
Feiyan Li
Yanchao Cui
Ziwen Li
Shiqiang Yan
Quanfeng Deng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1598151

632 views