Frontiers in Pharmacology | Renal Pharmacology

Original Research

Published on 20 Jul 2026

Integrating machine learning, deep learning, and docking to predict aristolochic acid A carcinogenesis

in Renal Pharmacology

Longzhu Li
Jiacheng Liao
Xintian Chen
Zeqiong Lin
Siqiao Gong
Junmin Huang
Ziqian Bi
Tianyang Wang
Xinliang Chia
Lu Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1873914

448 views

Review

Accepted on 16 Jul 2026

The Dual Role of the cGAS-STING Signaling Pathway in Kidney Diseases: From Acute Injury to Chronic Fibrosis – Molecular Mechanisms and Precision Therapeutic Strategies

in Renal Pharmacology

Guangdong Qi
Fei Xue
Hualin Sun
Xinlei Yao
Qingyuan Liu

Frontiers in Pharmacology

Review

Accepted on 14 Jul 2026

DIABETIC KIDNEY DISEASE WITHIN THE FRAMEWORK OF CARDIO-KIDNEY-METABOLIC HEALTH: A PARADIGM SHIFT

in Renal Pharmacology

Juarez R Braga
Joseph H Holthoff
Nithin Karakala
Fatima Ayub

Frontiers in Pharmacology

Review

Accepted on 13 Jul 2026

The Chemokine Network in Lupus Nephritis: Pathogenesis, Targeted Therapies, and Future Directions

in Renal Pharmacology

Chengye Wang
Liming Chen

Frontiers in Pharmacology

105 views

Original Research

Accepted on 13 Jul 2026

Bruceine A attenuates renal tubulointerstitial fibrosis via inhibiting Wnt7a/PI3K/AKT pathway

in Renal Pharmacology

Shuangyu Li
Renqing Wang
Tong Wang
Wenyan Zhang
Shengchun Xu
Zhenhua Ren
Renfei Luo

Frontiers in Pharmacology

Original Research

Accepted on 13 Jul 2026

Linear Dose-Response Relationship Between Vancomycin Trough Concentration and Acute Kidney Injury in Sepsis: Effect Modification by Hyperlactatemia

in Renal Pharmacology

Jing Tang
Daiyu Shen
Xun Zhou
Ling Xiao
Xinzhu Yuan
Bo Hu

Frontiers in Pharmacology

Original Research

Published on 10 Jul 2026

Paeoniflorin alleviates CKD-associated constipation by modulating TPH1/AHR-related signaling and suppressing NLRP3/GSDMD-mediated pyroptosis

in Renal Pharmacology

Jun Qiu
Zhimin Ao
Fenghua Yao
Jianing Zhang
Yong Wen
Yu Zhan

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1844043

741 views

Original Research

Accepted on 09 Jul 2026

Comparative Effectiveness of Finerenone Versus Steroidal Mineralocorticoid Receptor Antagonists on Sepsis-Induced Cardiomyopathy in Patients With Diabetic Kidney Disease: A Real-World Cohort Study

in Renal Pharmacology

Jheng-Yan Wu
Keng-Wei Lee
Sheng-Chi Huang
Hsuan-Yuan Chang
Yu Min Lin

Frontiers in Pharmacology

221 views

Review

Accepted on 09 Jul 2026

The pathological mechanisms and potential therapeutic strategies for renal anemia

in Renal Pharmacology

JiaXing Rao
Hao-Ming Zhou
Kim Fey Leu
Ming Liu
Ze-Feng Liu
Yu-Ping Tang

Frontiers in Pharmacology

Original Research

Accepted on 07 Jul 2026

Association of gut microbiome signatures with iron metabolism response to roxadustat in peritoneal dialysis patients with anemia: A cross-sectional study

in Renal Pharmacology

Jiangqing Fan
Xinqi Tan
Ying liu
Zhe Liu
Jialing Dai
Lulu Wang

Frontiers in Pharmacology

154 views

Review

Accepted on 06 Jul 2026

Gut Microbiota and Gut-Kidney Axis in Kidney Diseases: Therapeutic Potential and Perspectives of Natural Products

in Renal Pharmacology

Qianwei Wang
Jiahe Zhang
Ruiyan Chen
Junyan Song
Jinye Lv
Zhicheng Zhou
Lijuan Dai

Frontiers in Pharmacology

166 views

Correction

Accepted on 06 Jul 2026

Correction: Multidimensional mechanisms of natural products in modulating metabolic dysfunction–associated kidney disease: recent advances and future perspectives

in Renal Pharmacology

Yue Zhang
Jiarui Li
Qi Zhong
Mingda Han
Xiao Sun
Huili Huang
Shuang Zhao
Hao Xu
Kaile Ma
Xiangyan Li

Frontiers in Pharmacology

Original Research

Published on 06 Jul 2026

Clinical evaluation of rituximab combined with ACE inhibitors and statins in refractory nephrotic syndrome: associations with proteinuria, lipid profiles, and podocyte-related biomarkers

in Renal Pharmacology

Mengmeng Zhuang
Minguo Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1851207

457 views

Original Research

Published on 06 Jul 2026

Sodium bicarbonate combined with urokinase for the prevention and management of hemodialysis central venous catheter dysfunction

in Renal Pharmacology

Lin Lin
Lin-Jie Hu
Jia-Fei Geng
Ying Zhang
Zhi-Hui Li
Ye-Huan Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1775941

498 views

Original Research

Published on 02 Jul 2026

CX-01 mitigates trauma-induced acute kidney injury and improves survival in a combat-relevant polytrauma rat model

in Renal Pharmacology

Zhangsheng Yang
Caroline Gusson Shimoura
Heaven D. Sessions
Dustin M. Kneifel
Jeanette Rocha
Kassandra Gonzalez
Robert P. Willis
Emily M. Corbin
Venkata Yellepeddi
Brian J. Kirkwood

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1834668

671 views

Perspective

Accepted on 30 Jun 2026

Potential Nephroprotective Mechanisms of Orforglipron, an Oral Non-Peptide GLP-1 Receptor Agonist

in Renal Pharmacology

Prerana Ramadurgum
Joel Shah
Emily Shah
Biff F Palmer

Frontiers in Pharmacology

254 views

Original Research

Accepted on 29 Jun 2026

Sirolimus Application in Patients with Autoimmune-Associated Kidney Diseases Based on mTORC1 Activation: A Preliminary Exploration and Future Perspectives

in Renal Pharmacology

Chuanchuan Sun
Li Wan
Hui Gao
Yishan Ding
Zhen Qu
Feng Yu

Frontiers in Pharmacology

183 views

Original Research

Published on 26 Jun 2026

Wulingsan alleviates cisplatin-induced acute kidney injury and inhibits renal tubular epithelial cell apoptosis in association with the CaSR/CaMKKβ/AMPK pathway

in Renal Pharmacology

Xiuye Huang
Yuxian Li
Yongan Liao
Xiaotong Lin
Xipan Zhao
Xiaojie Li
Shengliang Yuan
Jiuyao Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1824226

719 views

Review

Published on 26 Jun 2026

Multidimensional mechanisms of natural products in modulating metabolic dysfunction–associated kidney disease: recent advances and future perspectives

in Renal Pharmacology

Yue Zhang
Jiarui Li
Qi Zhong
Mingda Han
Xiao Sun
Huili Huang
Shuang Zhao
Hao Xu
Kaile Ma
Xiangyan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1881128

586 views

Original Research

Accepted on 25 Jun 2026

Polyphyllin II attenuates renal fibrosis in diabetic kidney disease partly through regulation of autophagy and PI3K/AKT/mTOR signaling

in Renal Pharmacology

筱竹孙
慧欣毕
欣芳覃

Frontiers in Pharmacology

219 views

Review

Published on 24 Jun 2026

The dysregulated unfolded protein response in diabetic kidney disease: mechanisms and crosstalk with cell death pathways

in Renal Pharmacology

Hao Zhang
Kaixiang Li
Jia Ma
Ling Ma
Muhammad Asad Farooq
Jing E

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1875777

721 views

Original Research

Published on 24 Jun 2026

Protective role of Bergenia ciliata in artesunate-induced nephrotoxicity: a translational pharmacology study integrating in-silico and experimental evidence

in Renal Pharmacology

Sudip Prasad Jena
Sabina Evan Prince

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1862707

637 views

Review

Published on 18 Jun 2026

The role of mitochondria in the gut-kidney axis: implications for kidney health

in Renal Pharmacology

Qin Hu
Hua Jin
Lan Hu
Xu Li

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1851705

718 views

Correction

Published on 12 Jun 2026

Correction: Licochalcone A mitigates cisplatin-induced nephrotoxicity by inhibiting ferroptosis and mitochondrial dysfunction via the Nrf2/GPX4 axis

in Renal Pharmacology

Mo Han
Feihu Zhang
Mengyuan Li
Qixiang Zhang
Kaidi Shen
Depeng Zhang
Huanke Xu
Fang Zhou
Xinyu Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1876105

554 views

791 articles

articles

Integrating machine learning, deep learning, and docking to predict aristolochic acid A carcinogenesis

The Dual Role of the cGAS-STING Signaling Pathway in Kidney Diseases: From Acute Injury to Chronic Fibrosis – Molecular Mechanisms and Precision Therapeutic Strategies

DIABETIC KIDNEY DISEASE WITHIN THE FRAMEWORK OF CARDIO-KIDNEY-METABOLIC HEALTH: A PARADIGM SHIFT

The Chemokine Network in Lupus Nephritis: Pathogenesis, Targeted Therapies, and Future Directions

Bruceine A attenuates renal tubulointerstitial fibrosis via inhibiting Wnt7a/PI3K/AKT pathway

Linear Dose-Response Relationship Between Vancomycin Trough Concentration and Acute Kidney Injury in Sepsis: Effect Modification by Hyperlactatemia

Paeoniflorin alleviates CKD-associated constipation by modulating TPH1/AHR-related signaling and suppressing NLRP3/GSDMD-mediated pyroptosis

Comparative Effectiveness of Finerenone Versus Steroidal Mineralocorticoid Receptor Antagonists on Sepsis-Induced Cardiomyopathy in Patients With Diabetic Kidney Disease: A Real-World Cohort Study

The pathological mechanisms and potential therapeutic strategies for renal anemia

Association of gut microbiome signatures with iron metabolism response to roxadustat in peritoneal dialysis patients with anemia: A cross-sectional study

Gut Microbiota and Gut-Kidney Axis in Kidney Diseases: Therapeutic Potential and Perspectives of Natural Products

Correction: Multidimensional mechanisms of natural products in modulating metabolic dysfunction–associated kidney disease: recent advances and future perspectives

Clinical evaluation of rituximab combined with ACE inhibitors and statins in refractory nephrotic syndrome: associations with proteinuria, lipid profiles, and podocyte-related biomarkers

Sodium bicarbonate combined with urokinase for the prevention and management of hemodialysis central venous catheter dysfunction

CX-01 mitigates trauma-induced acute kidney injury and improves survival in a combat-relevant polytrauma rat model

Potential Nephroprotective Mechanisms of Orforglipron, an Oral Non-Peptide GLP-1 Receptor Agonist

Sirolimus Application in Patients with Autoimmune-Associated Kidney Diseases Based on mTORC1 Activation: A Preliminary Exploration and Future Perspectives

Wulingsan alleviates cisplatin-induced acute kidney injury and inhibits renal tubular epithelial cell apoptosis in association with the CaSR/CaMKKβ/AMPK pathway

Multidimensional mechanisms of natural products in modulating metabolic dysfunction–associated kidney disease: recent advances and future perspectives

Polyphyllin II attenuates renal fibrosis in diabetic kidney disease partly through regulation of autophagy and PI3K/AKT/mTOR signaling

The dysregulated unfolded protein response in diabetic kidney disease: mechanisms and crosstalk with cell death pathways

Protective role of Bergenia ciliata in artesunate-induced nephrotoxicity: a translational pharmacology study integrating in-silico and experimental evidence

The role of mitochondria in the gut-kidney axis: implications for kidney health

Correction: Licochalcone A mitigates cisplatin-induced nephrotoxicity by inhibiting ferroptosis and mitochondrial dysfunction via the Nrf2/GPX4 axis