Frontiers in Pharmacology | Translational Pharmacology

Review

Published on 09 Sep 2026

Research progress on protein lactylation in female reproductive disease: molecular mechanisms, functions, and therapeutic implications

in Translational Pharmacology

Xiaoyang Shen
Yan Chen
Hongxia Deng
Nannan Zhang
Liangzhi Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1867863

383 views

Original Research

Accepted on 08 Sep 2026

Ensemble Signal Detection Reveals Target-Specific Temporal Risk of Hypokalemia After Immune Checkpoint Inhibition: A Translational Pharmacology Framework

in Translational Pharmacology

Xuewen Jiang
Shengwang Chen
Ziyi Dai
Zihan Guo
Ziyi Li
Ruiqi Liu

Frontiers in Pharmacology

Original Research

Published on 08 Sep 2026

Targeting SIRT3 dysfunction with a sprayable honokiol hydrogel for diabetic burn wound repair

in Translational Pharmacology

Min Li
Xuedong Yu
Huantao Hu
Kai Wen
Qiongfang Ruan
Paul Yao
Maolong Dong

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1912136

527 views

Original Research

Accepted on 07 Sep 2026

Population Cellular Kinetics and Exposure-CRS Analysis of CAR-T Cells in Chinese Patients with Relapsed/Refractory B-ALL

in Translational Pharmacology

Yicong Bian
Jinjie Yuan
Chenrong Huang
Kaijie Zhang
Ling Xue
Fan Xia
Liqing Kang
Yan Wang
Hua Zhang
Lei Yu

Frontiers in Pharmacology

Editorial

Published on 04 Sep 2026

Editorial: Emerging targeted and immunotherapeutic strategies in oncology: from solid tumors to hematologic malignancies

in Translational Pharmacology

Ximena Maria Muresan
Adrian Bogdan Tigu
Andrei Roman
Arianna Romani

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1965471

704 views

Original Research

Published on 04 Sep 2026

Median effective dose and 95% effective dose of oliceridine combined with ciprofol for painless gastroscopy: a dose-finding study based on Dixon’s up-and-down method

in Translational Pharmacology

Xikun Sun
Pei Song
Bin Zou
Yimeng Zhuang
Xiaohang Han
Jianyu Zu
Yugang Diao

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1918438

1,883 views

Review

Published on 03 Sep 2026

Vitamin D in male reproduction: molecular mechanisms and pharmacological perspectives

in Translational Pharmacology

Jing Liu
Bang Liu
Xingyun Qiu
Mengmei Lv
Shasha Liu
Dai Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1849299

342 views

Review

Published on 02 Sep 2026

The multifaceted functions of lactate and its translational potentials in cancer

in Translational Pharmacology

Ping Wang
Xia Yang
Yunfei Yan
Qiang Fu
Jinxia Hu
Sen Xu
Xin Wang
Fei Jiao

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1881938

473 views

Review

Published on 01 Sep 2026

Microbiota-mitochondria axis in neurodegenerative disorders and retinal dysfunction: mechanisms and emerging therapeutic opportunities

in Translational Pharmacology

Puneet K. Samaiya
Akshat Agrawal
Shrija Kesharwani
Rini Sathe
Santosh Kumar Prajapati
Shreyasi Majumdar

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1889898

549 views

Original Research

Published on 01 Sep 2026

Preclinical pharmacokinetic modeling and clinical translation of SIG001, a novel anti-cancer therapeutic antibody targeting on cancer-derived sialylated IgG

in Translational Pharmacology

Qingyu Yao
Chen Liu
Shenghua Zhang
Yaou Liu
Ying Zhou
Xiaoyan Qiu

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1904283

555 views

Clinical Trial

Published on 01 Sep 2026

Bioavailability of a novel anti-influenza agent, onradivir granules, in healthy Chinese adults: a first-in-human study

in Translational Pharmacology

Xiaoyi Yi
Yuting Liu
Xiaosong Wang
Yahui Peng
Jian Fu
Youyun Li
Haijun Li
Hong Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1905152

513 views

Mini Review

Published on 01 Sep 2026

A review bridging pharmacokinetics, preclinical data, and human evidence on curcuminoids in cardiovascular disease

in Translational Pharmacology

Katarzyna Zolnik
Andrzej Mogielnicki
Bartlomiej Kalaska

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1906759

538 views

Clinical Trial

Published on 31 Aug 2026

Pharmacokinetics and safety comparison of cycloserine capsules and their generic counterpart: a randomized, open-label, two-period, two-sequence, single-dose crossover bioequivalence study in healthy Chinese subjects

in Translational Pharmacology

Xiuqing Peng
Liying Zhang
Caiyun Jia
Congyang Ding
Haojing Song
Zhanjun Dong
Huizhen Wu
Wanjun Bai

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1801953

482 views

Original Research

Accepted on 27 Aug 2026

A Non-Destructive Methodological Framework for Modernizing Legacy Clinical Reporting Systems for AI-Driven Pharmacoinformatics: A SAS Case Study

in Translational Pharmacology

Jaime Yan

Frontiers in Pharmacology

102 views

Case Report

Accepted on 26 Aug 2026

Case Report: Massive Sustained-Release Valproate Overdose With Prolonged Gastric Tablet Retention and Partial Pharmacobezoar Formation Managed by Endoscopic Removal and Delayed Extracorporeal Therapy

in Translational Pharmacology

POCHEN LI
Yang Wu
Qianping Zhang
Danxia Ge
Yujiao Li
Fangyu Yu

Frontiers in Pharmacology

162 views

Methods

Accepted on 25 Aug 2026

A Novel Provocation Protocol to Identify Nocebo Effects in Clinical Practice - A Proof-of-Concept n-of-1 Study

in Translational Pharmacology

Martin Coenen
Gunther Hartmann
Thomas Büttner

Frontiers in Pharmacology

188 views

Original Research

Published on 25 Aug 2026

A population pharmacokinetic model library for polymyxin B: clinical implementation of model-informed precision dosing

in Translational Pharmacology

Shimin Wang
Xiaoyan Cui
Lili Li
Lijie Kang
Guangjie Hou

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1900585

391 views

Review

Published on 25 Aug 2026

Protease-activated receptor 1 in diabetes and its chronic complications: signaling mechanisms and emerging therapeutic advances

in Translational Pharmacology

Yanrui Wei
Bing Wang
Qiuyue Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1891733

843 views

Review

Accepted on 21 Aug 2026

Orlistat: A Comprehensive Review of a Lipase Inhibitor from Obesity Management to Emerging Oncological Applications

in Translational Pharmacology

Yuchao Hao
Li Li

Frontiers in Pharmacology

444 views

Original Research

Accepted on 21 Aug 2026

Bioequivalence Study of Two Formulations of a Sitagliptin/Metformin Hydrochloride Extended-Release Tablet in Healthy Chinese Subjects Under Fasting and Fed Conditions: A Randomized, Open-Label, Single-Dose, Crossover Trial

in Translational Pharmacology

Lin Fang
Xin Li
Rongxin Ban
Chenjing Wang
Yi Xu
Lipeng Xue
Ping Shi
Feifei Sun
Yu Cao

Frontiers in Pharmacology

273 views

Review

Accepted on 21 Aug 2026

Mechanism-Aware and Safety-Validated AI for Drug Repurposing: A Critical Review and Translational Pharmacology Framework

in Translational Pharmacology

Moumita Hazra

Frontiers in Pharmacology

223 views

Original Research

Accepted on 21 Aug 2026

A Preliminary Study of a Machine-Learning Prediction Model for Lung Cancer Diagnosis Based on Routine Blood Indicators and Traditional Chinese Medicine (TCM) Diagnostic Parameters

in Translational Pharmacology

Zhanhui Lu
Chengcheng Zhang
Yiyi Liu
Jingru Qin
Lu Yang
Qianqian Yin
Zhijing RAO
Junqing Ji
Kaiting Chen
Wan Su

Frontiers in Pharmacology

269 views

Review

Accepted on 21 Aug 2026

Revolutionizing Transdermal Drug Delivery Evaluation: The Evolution from Traditional Models to Skin Organoids and the Integration of Artificial Intelligence

in Translational Pharmacology

Xinqiang Mo
Mingshi Qiu
Ru Song
Zhenjie Wu
Chunyan Liu
Linqi Su
Haiyi Wang
Rui Xue
Lu Yu
Maoyao Wang

Frontiers in Pharmacology

206 views

Original Research

Published on 21 Aug 2026

Plasma untargeted metabolomics reveals promising diagnostic metabolites for adrenocortical carcinoma

in Translational Pharmacology

Yihui Yang
Shuping Shi
Jianqiang Wu
Tingting Xu
Junmei Shang
Jiaxin Yu
Bo Zhang
Xin Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1817514

532 views

1,202 articles

articles

Research progress on protein lactylation in female reproductive disease: molecular mechanisms, functions, and therapeutic implications

Ensemble Signal Detection Reveals Target-Specific Temporal Risk of Hypokalemia After Immune Checkpoint Inhibition: A Translational Pharmacology Framework

Targeting SIRT3 dysfunction with a sprayable honokiol hydrogel for diabetic burn wound repair

Population Cellular Kinetics and Exposure-CRS Analysis of CAR-T Cells in Chinese Patients with Relapsed/Refractory B-ALL

Editorial: Emerging targeted and immunotherapeutic strategies in oncology: from solid tumors to hematologic malignancies

Median effective dose and 95% effective dose of oliceridine combined with ciprofol for painless gastroscopy: a dose-finding study based on Dixon’s up-and-down method

Vitamin D in male reproduction: molecular mechanisms and pharmacological perspectives

The multifaceted functions of lactate and its translational potentials in cancer

Microbiota-mitochondria axis in neurodegenerative disorders and retinal dysfunction: mechanisms and emerging therapeutic opportunities

Preclinical pharmacokinetic modeling and clinical translation of SIG001, a novel anti-cancer therapeutic antibody targeting on cancer-derived sialylated IgG

Bioavailability of a novel anti-influenza agent, onradivir granules, in healthy Chinese adults: a first-in-human study

A review bridging pharmacokinetics, preclinical data, and human evidence on curcuminoids in cardiovascular disease

Pharmacokinetics and safety comparison of cycloserine capsules and their generic counterpart: a randomized, open-label, two-period, two-sequence, single-dose crossover bioequivalence study in healthy Chinese subjects

A Non-Destructive Methodological Framework for Modernizing Legacy Clinical Reporting Systems for AI-Driven Pharmacoinformatics: A SAS Case Study

Case Report: Massive Sustained-Release Valproate Overdose With Prolonged Gastric Tablet Retention and Partial Pharmacobezoar Formation Managed by Endoscopic Removal and Delayed Extracorporeal Therapy

A Novel Provocation Protocol to Identify Nocebo Effects in Clinical Practice - A Proof-of-Concept n-of-1 Study

A population pharmacokinetic model library for polymyxin B: clinical implementation of model-informed precision dosing

Protease-activated receptor 1 in diabetes and its chronic complications: signaling mechanisms and emerging therapeutic advances

Orlistat: A Comprehensive Review of a Lipase Inhibitor from Obesity Management to Emerging Oncological Applications

Bioequivalence Study of Two Formulations of a Sitagliptin/Metformin Hydrochloride Extended-Release Tablet in Healthy Chinese Subjects Under Fasting and Fed Conditions: A Randomized, Open-Label, Single-Dose, Crossover Trial

Mechanism-Aware and Safety-Validated AI for Drug Repurposing: A Critical Review and Translational Pharmacology Framework

A Preliminary Study of a Machine-Learning Prediction Model for Lung Cancer Diagnosis Based on Routine Blood Indicators and Traditional Chinese Medicine (TCM) Diagnostic Parameters

Revolutionizing Transdermal Drug Delivery Evaluation: The Evolution from Traditional Models to Skin Organoids and the Integration of Artificial Intelligence

Plasma untargeted metabolomics reveals promising diagnostic metabolites for adrenocortical carcinoma