Frontiers in Pharmacology | Translational Pharmacology

Original Research

Published on 06 Jan 2026

Synergistic therapy for diabetic retinopathy via dual blockade of VEGF-A and TNF-α with a bispecific nanobody

in Translational Pharmacology

Chenlu Wu
Yue Shen
Chengnan Xu
Chong Bi
Chenyue Yan
Jinping Niu
Wenyun Zheng
Xingyuan Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1729606

134 views

Opinion

Published on 05 Jan 2026

What role will physiological resilience play in brown-white fat dynamic in obesity management?

in Translational Pharmacology

Oksana Zayachkivska
Iryna Kovalchuk
Iryna Muzyka
Maryana Savytska

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1691149

309 views

Review

Accepted on 02 Jan 2026

HtrA2/Omi: Potential therapeutic targets for neurodegenerative diseases

in Translational Pharmacology

Liting Xu
Min Zeng

Frontiers in Pharmacology

Editorial

Accepted on 24 Dec 2025

Editorial: Nutrition as a Pharmacological Approach to Metabolic Disorders and Ageing

in Translational Pharmacology

Chiara Ruocco
Amit Kumar Singh
Enzo Nisoli
Maurizio Ragni

Frontiers in Pharmacology

136 views

Correction

Accepted on 19 Dec 2025

Correction: Rubidium Chloride Targets Jnk/p38-Mediated NF-κB Activation to Attenuate Osteoclastogenesis and Facilitate Osteoblastogenesis

in Translational Pharmacology

Zhengxiao Ouyang
Qianli Huang
Bin Liu
Hong Wu
Tang Liu
Yong Liu

Frontiers in Pharmacology

115 views

Correction

Accepted on 19 Dec 2025

Correction: Hesperetin Prevents Bone Resorption by Inhibiting RANKL-Induced Osteoclastogenesis and Jnk Mediated Irf-3/c-Jun Activation

in Translational Pharmacology

Qiang Zhang
Xinqiao Tang
Zhong Liu
Xiaoxia Song
Dan Peng
Wei Zhu
Zhengxiao Ouyang
Wanchun Wang

Frontiers in Pharmacology

Review

Published on 19 Dec 2025

Engineering immunity with CAR-NK cells: advancing the frontiers of cancer immunotherapy

in Translational Pharmacology

Vlad Andrei Cianga
Ion Antohe
Cosmin Minciună
Angela Dăscălescu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1738558

820 views

Original Research

Accepted on 18 Dec 2025

PTX-Loaded, Polysorbate 80-Functionalized Brain-Targeting Pullulan Nanoparticles for Drug Delivery

in Translational Pharmacology

Huabing Yuan
Lu Han
Hao Deng
Yue Tan
Yi Yang
Yi Liu
Jiaxin Ying
Mengqi Fang
Hui Wei
Zhihe Tao

Frontiers in Pharmacology

173 views

Review

Published on 12 Dec 2025

Relevant pharmacokinetics, bioavailability, and bioequivalence studies on Chlorpheniramine maleate (various species): a review

in Translational Pharmacology

César Alas-Pineda
Dennis J. Pavón-Varela
Kristhel Gaitán-Zambrano
Gustavo Ferrer

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1737690

1,177 views

Correction

Published on 11 Dec 2025

Correction: Cimifugin suppresses NF-κB signaling to prevent osteoclastogenesis and periprosthetic osteolysis

in Translational Pharmacology

Juan Duan
Xuantao Hu
Tao Li
Gen Wu
Pengcheng Dou
Zhengxiao Ouyang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1678203

352 views

Original Research

Published on 10 Dec 2025

Real-world patient outcomes with Blinatumomab and Inotuzumab in adult relapsed/refractory B-cell acute lymphoblastic leukemia: a retrospective analysis from two Romanian oncology centers

in Translational Pharmacology

Ion Antohe
Amalia Titieanu
Vlad Andrei Cianga
Cosmin Minciună
Cătălin Dănăilă
Alina Daniela Tănase
Iuliu Ivanov
Loredana Dragoş
Mihaela Zlei
Mihaela Mențel

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1684382

769 views

Original Research

Published on 10 Dec 2025

Real-world data analysis of the risk of Fournier’s gangrene in patients using sodium-glucose cotransporter 2 inhibitors (SGLT2i)

in Translational Pharmacology

Moritz Hertel
Hanno Jaoulak
Max Heiland
Susanne Nahles
Robert Preissner
Saskia Preissner

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1643866

659 views

Review

Published on 09 Dec 2025

Pharmacological effects and application prospects of mussel adhesive proteins

in Translational Pharmacology

Junsha An
Zengmiao Hou
Jiaqi Li
Qian Bi
Shile Huang
Cheng Peng
Fu Peng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1704475

815 views

Original Research

Accepted on 08 Dec 2025

Refined Target-mediated Drug Disposition Modeling of the Anti-Tissue Factor Pathway Inhibitor Antibody MG1113 in Cynomolgus Monkeys and Rabbits

in Translational Pharmacology

Heechun Kwak
Yoo-Seong Jeong
Jiyoung Kim
Minsoo Lee
Seonyoung Byoun
Yasunori Aoki
Suk-Jae Chung
Wooin Lee

Frontiers in Pharmacology

199 views

Original Research

Published on 08 Dec 2025

Pterostilbene mitigates the senescence of human dermal fibroblast cells by enhancing mitochondrial quality

in Translational Pharmacology

Xinyu Zhou
Ning Wang
Jihua Wei
Guizhi Li
Zhengwei Lue
Chang Liu
Qi Bao
Zhe Feng
Minjie Zhang
Hu Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1732154

1,153 views

Correction

Published on 08 Dec 2025

Correction: DICAR/DICAR-JP exerts therapeutic effects in brain stroke via the miR-361-5p/PRMT1 pathway

in Translational Pharmacology

Zhijun Yu
Aihua Jiang
Kai Yang
Lin Zhan
Zifei Xiang
Li Chen
Zheng Kuai
Qiong Yuan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1756716

406 views

Original Research

Published on 03 Dec 2025

Essential amino acids preserve intestinal barrier integrity via mitochondrial protection in obesity and gut inflammation

in Translational Pharmacology

Letizia Spataro
Maurizio Ragni
Agnese Segala
Alice Vetturi
Giulia Sofia Marcotto
Luca Canciani
Michele O. Carruba
Roberto Aquilani
Ginetta Collo
Alessandra Valerio

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1694723

1,270 views

Original Research

Published on 03 Dec 2025

Dendrobine promotes bone formation via the canonical Wnt/β-catenin signaling pathway and prevents postmenopausal osteoporosis

in Translational Pharmacology

Shengfa Li
Peili Liang
Jian Chen
Youming Zhang
Haixiong Miao
Ting Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1616070

771 views

Original Research

Accepted on 28 Nov 2025

Donor Lymphocyte Infusion Combined with Azacitidine After Allogeneic HSCT in Pediatric AML: A Single-Center Retrospective Analysis

in Translational Pharmacology

Ana Maria Bica
Andra Daniela Marcu
Cristina Georgiana Jercan
Iuliana Iordan
Andreea Serbanica
Irina Avramescu
Matei Colita
Delia Codruta Popa
Ileana Constantinescu
Alexandra Mihaela Ichim

Frontiers in Pharmacology

180 views

Original Research

Published on 28 Nov 2025

Preclinical evaluation of uPAR-ICG-FVIOs for dual-mode imaging and magnetic hyperthermia therapy in pancreatic cancer

in Translational Pharmacology

Tao Luo
Kelan Zhang
Chong Wu
Xiaolong Wu
Haojie Yang
Zhigang Chen
Fen Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1681718

1,115 views

Review

Published on 28 Nov 2025

Part 1 - imidazolines and the changing face of nasal decongestants

in Translational Pharmacology

Rebecca J. Stinson
Laura R. Sadofsky

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1655252

1,259 views

Review

Published on 28 Nov 2025

Part II – imidazolines and rhinitis medicamentosa: how can we tackle the rebound dilemma?

in Translational Pharmacology

Rebecca J. Stinson
Laura R. Sadofsky

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1655254

1,529 views

Case Report

Published on 27 Nov 2025

Case Report: A pharmacist-led precision therapy framework for managing invasive fungal infection in CSF1R-Related leukoencephalopathy post Allo-HSCT

in Translational Pharmacology

Jin Lu
Mengqi Jia
Xinghua Luan
Zhongqiu Zhang
Jingying Wu
Xiaojun Huang
Li Yang
Xincai Zhao
Miaomiao Zhou
Yao Fu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1656503

905 views

Original Research

Published on 27 Nov 2025

DICAR/DICAR-JP exerts therapeutic effects in brain stroke via the miR-361-5p/PRMT1 pathway

in Translational Pharmacology

Zhijun Yu
Aihua Jiang
Kai Yang
Lin Zhan
Zifei Xiang
Li Chen
Zheng Kuai
Qiong Yuan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1721188

702 views