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Featured news

16 Dec 2022

Screening a puppy’s DNA methylome may help predict how energetic or fearful they will be

By Mischa Dijkstra, Frontiers science writer Scientists found that differences in the epigenome, in particular the DNA methylome, are predictably associated with differences in the temperament of dogs, especially their energy and fearfulness. The DNA methylome predicted these traits better than Single-Locus Polymorphisms or age. In future, breeders could screen the epigenome of puppies to find the best candidates for companion or service dogs. Anyone who’s ever had a dog knows how different one can be from another. For example, they can be reserved or friendly, playful or calm, fearful or bold, and prone to bark or fetch or not. Research has shown that some of these differences are genetically determined. But even within dog breeds, where line breeding and artificial selection have led to the loss of much of the original genetic variation, the behavior of individuals can differ widely. Now, researchers show that part of the differences in temperament – in particular  their ‘energy’ level and fear-related behaviors – depend on acquired differences in the epigenome. The epigenome, an individual’s unique set of chemical tags on DNA and its associated histone complexes (nucleosomes), can dial the expression of local genes up or down. Because the epigenome is known […]

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15 Dec 2022

Five articles you need to check out on the future of neurology research

By Colm Gorey, Frontiers Science Communications Manager Image: Shutterstock.com In an ever-changing field of research such as neurology, it can be difficult to keep up with the latest breakthroughs. Now at Frontiers, we highlight just three of the latest research articles to shed more light on how the mind works. The human brain is an organ that has fascinated our species for centuries, with vast amounts of research so far yielding a wealth of discoveries. However, so much of how the brain works remains a mystery waiting to be solved. In 2022, Frontiers published one of the biggest neurological research breakthroughs of the year with the discovery that life may indeed flash before our eyes as we die. However, this was just one paper of thousands published by Frontiers this year that helped set the groundwork for new neurological discoveries, ranging from multiple sclerosis to deep brain stimulation. Five such articles are essential reading to anyone looking to learn more about neurology were published as part of the research topic ‘Horizons in Neurology’. The Neuroimmunology of Multiple Sclerosis: Fictions and Facts There have been tremendous advances in the neuroimmunology of multiple sclerosis (MS) over the past five decades, which have […]

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13 Dec 2022

The (un)fair allocation of scarce vaccines and how maths can provide a solution

By Prof Carlos Alós-Ferrer Prof Carlos Alós-Ferrer. Image: Nomis Foundation The Covid-19 global vaccine roll-out is considered one of the greatest achievements in modern medical history, saving hundreds of thousands of lives. However, it was marred by decisions that saw those most in need of a vaccine in some countries wait too long, while those perceived to be least at risk getting them first. Now, Prof Carlos Alós-Ferrer of the University of Zurich writes about how he and his colleagues’ latest research in Frontiers in Public Health shows that one maths procedure can ensure a fair distribution of scarce vaccines across the globe. Remember when Covid-19 vaccines first became available? After many months of lockdowns and  increasing casualty rates, people across the planet were allowed to exhale a collective sigh of relief.  However, as is always the case when new vaccines are developed, there were not enough doses for all who wanted them. Rationing had to be imposed. Unfortunately, the rationing procedures violated elementary ethical principles, which might have led to some elderly and at-risk patients being neglected while younger, healthier citizens were already vaccinated. How did it go wrong? Vaccine acquisition and allocation across the world was as centralized […]

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13 Dec 2022

Western Michigan University Homer Stryker M.D. School of Medicine forms publishing agreement with Frontiers

Western Michigan University Homer Stryker M.D. School of Medicine Library has formed an institutional membership agreement for open access publishing with Frontiers. To qualify for funding to cover some or all of the publishing costs, affiliated corresponding authors are required to contact the Medical Library to obtain a PO number to be preapproved prior to submitting their manuscript to any Frontiers journal. Articles may also benefit from a 2.5% membership discount. The Western Michigan University Homer Stryker M.D. School of Medicine library supports its researchers in making their research more widely available. This agreement will further encourage Western Michigan University Homer Stryker M.D. School of Medicine researchers to publish open access, increasing the volume of research openly available. While this reduces costs for the researcher, it also benefits the wider research community and the public at large.   For more information on Frontiers’ institutional agreements please visit our institutional memberships page or contact institutions@frontiersin.org to discuss the possibilities for your own organization.  Information for researchers  If you are a Western Michigan University Stryker School of Medicine researcher, please contact the Medical Library to obtain a PO number to be preapproved to cover some or all of the publishing costs prior to submission. Once […]

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09 Dec 2022

Evolution of bat wings and calls through ‘foraging syndromes’ allows diversity to flourish

By Mischa Dijkstra, Frontiers science writer Egyptian slit-faced bats, Nycteris thebaica In a new study, scientists show that the wing shape and the echolocation frequency of bats are tightly linked across species. This pattern could only be identified because of the large dataset in the present study, which allowed the authors to look beyond the effect of bat family on these traits. The results mean that wing shape and echolocation frequency have jointly evolved in response to foraging ecology, yielding an optimal combination of traits or ‘foraging syndrome’ in each habitat. Bats are an evolutionary success story. With approximately 1,400 species living today, they thrive in every environment except the polar regions. They come in a remarkable range of sizes, from the golden-crowned flying fox with a mass of 1.2 kg and a wingspan of 171 cm, to Kitti’s hog-nosed ‘bumblebee’ bat with a mass of 2 g and a wingspan of 33 cm. The frequencies that bats emit during echolocation are also highly variable, ranging from 11 kHz to 212 kHz. But what has driven the evolution of this extraordinary diversity? “Here we show with that among bat species, there is a close correspondence between wing shape and the […]

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08 Dec 2022

Flocking to fire: wildfires don’t deter Americans from moving to at-risk regions

by Angharad Brewer Gillham, Frontiers science writer Image/Shutterstock.com Scientists investigated whether environmental hazards put people off moving to regions at risk and found that heatwaves and hurricanes deter newcomers, but wildfires don’t. The climate crisis has caused humans to move both within their countries of origin and across borders. Although climate migration is often treated as a phenomenon of the ‘global south’, a team of scientists led by Mahalia Clark at the University of Vermont (UVM) turned the spotlight on the US. The US has experienced numerous destructive weather events recently, which have killed and injured many people and done billions of dollars of damage. But the team found that despite the death toll, more people are moving to areas in the United States that are at serious risk of wildfires. “Our original motivation was the increasing number of headlines each year about record breaking heat waves, hurricanes, and wildfires,” said Clark, a researcher at UVM’s Gund Institute for Environment. “I had been studying natural amenities — features of the climate and environment that are attractive to movers — but I began to wonder if the threat of these hazards might have a deterring effect on migration.” Read original article […]

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07 Dec 2022

Could new cancer drugs come from potatoes and tomatoes?

by Angharad Brewer Gillham, Frontiers science writer Image/Shutterstock.com Polish scientists revealed the potential for new cancer drugs to be formulated from bioactive compounds found in plants from the genus Solanum, like potatoes and aubergines. Everyone knows someone who has had cancer. In 2020, around 19m new cases — and around 10m deaths — were registered worldwide. Treatments are improving all the time but can damage healthy cells or have severe side-effects which are hard on patients; in the search for new, more targeted cancer drugs, traditional medicine offers many possible candidates. A team of Polish scientists led by Magdalena Winkiel at Adam Mickiewicz University, publishing today in Frontiers in Pharmacology, reviewed the bioactive compounds called glycolalkaloids that are found in many vegetables that are household names, like potatoes and tomatoes, to demonstrate their potential to treat cancer. “Scientists around the world are still searching for the drugs which will be lethal to cancer cells but at the same time safe for healthy cells,” said Winkiel. “It is not easy despite the advances in medicine and powerful development of modern treatment techniques. That is why it might be worth going back to medicinal plants that were used years ago with success […]

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06 Dec 2022

10 Frontiers articles that caught the world’s attention in 2022

By Frontiers’ science writers Image: Shutterstock.com As part of Frontiers’ passion to make science available to all, we highlight just a small selection of the most fascinating research published with us each month to help inspire current and future researchers to achieve their research dreams. 2022 was no different, and saw many game-changing discoveries contribute to the world’s breadth of knowledge on topics ranging from the climate crisis to robotics, and exercise to the lives of our ancestors. So to round of the year, here are 10 Frontiers articles from this year that got the world’s top media talking. 1. This illusion, new to science, is strong enough to trick our reflexes Have a look at the image below. Do you perceive that the central black hole is expanding, as if you’re moving into a dark environment, or falling into a hole? If so, you’re not alone: a study published to Frontiers in Human Neuroscience showed that this ‘expanding hole’ illusion, which is new to science, is perceived by approximately 86% of people. The researchers don’t yet know why a minority seem unsusceptible to the ‘expanding hole’ illusion. Nor do they know whether other vertebrate species, or even nonvertebrate animals […]

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05 Dec 2022

Scientists find inorganic food additives might make babies more vulnerable to allergies

By Angharad Brewer Gillham, Frontiers science writer Image/Shutterstock.com Inorganic nanoparticles used to help process food may be crossing the placental barrier and getting into breastmilk, potentially damaging intestinal regulation and compromising babies’ oral tolerance, predisposing them to food allergies. Nanotechnologies have revolutionized food technology with changes to food production, manufacture, and processing that are intended to make our food safer and healthier. Phytosanitary products, processing aids, food additives, and surfaces that touch food in storage can all transfer nanoparticles that might be consumed by humans. In a review published in Frontiers in Allergy today, Mohammad Issa, at the Université Paris-Saclay, and colleagues pointed out that such a significant change to food production could have unforeseen health consequences. The team presented evidence that suggested that nanoparticles not only cross the placenta to reach developing fetuses but leave them at greater risk of potentially life-threatening food allergies. “Due to the immunotoxic and biocidal properties of nanoparticles, exposure may disrupt the host-intestinal microbiota’s beneficial exchanges and may interfere with intestinal barrier and gut-associated immune system development in fetus and neonate,” said Dr Karine Adel-Patient, corresponding author of the study. “This may be linked to the epidemic of immune-related disorders in children, such as […]

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02 Dec 2022

Open access publisher Frontiers strengthens its global public affairs team

Research publisher Frontiers appoints Dr Anke Beck and Ms Nancy (Yinan) Chen as heads of public affairs and advocacy for Europe and China respectively. They have been appointed to lead advocacy initiatives in support of Frontiers’ mission to make all science open.  Europe and China are the unique hubs for research and high-potential innovations. The diverse nature of these research communities requires stronger links between academia and policy makers in line with regional or national smart specialization strategies. It also requires a deep understanding of the different stakeholders and their needs, as well as the willingness to engage and collaborate on all sides. Anke and Nancy’s deep knowledge of the challenges, as well as their combined twenty-two years’ industry experience, makes them perfectly suited to reinforce Frontiers’ community engagement.  Photo credit: Frontiers Over the past ten years, Dr Anke Beck has been at the forefront of open access publishing. As a managing director at Walter de Gruyter, she was responsible for the portfolio growth in both traditional and open access publishing. To maintain a market-leading position in open access book publishing, Anke took the role of chief executive officer of IntechOpen, where she developed new institutional partnerships across academia. In 2018, she […]

Featured news

02 Dec 2022

‘The Maya had, and continue to have, a creative impact on forest composition’ – Dr Anabel Ford

El Pilar, an ancient Maya site in Belize In our Frontier Scientists series, we talk to Dr Anabel Ford, a leading researcher on the ancient Maya, about her career and research interests. Ford recently published a study in Frontiers in Ecology and Evolution in which she stressed the importance of the traditional milpa land use system for the Maya civilization, not only in the Classical Period, but also today. Dr Anabel Ford is a US archeologist who specializes in the ancient Maya of Central America. In 1983, she led the team that encountered the ancient Maya city of El Pilar in Belize. Ford is a faculty member of the Institute of Social Behavioral and Economic Research at the University of California Santa Barbara and the director of the MesoAmerican Research Center at the same university. She is an expert on the still-flourishing forest gardens of the Maya region, built up over several millennia of traditional land use by the Maya people. Recently she published the study, “Scrutinizing the paleoecological record of the Maya forest” in Frontiers in Ecology and Evolution. In the paper, she focuses on the traditional milpa-forest garden cycle, where maize, beans, squashes, tomatoes, and many others are […]

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30 Nov 2022

How to write a manuscript: Expert advice on getting published

By: John R. Porter, Helen Kimbell, Aida Finn, Catarina Alves, and Bhagirath Chauhan There’s a saying in science – ‘publish or perish’, meaning your ability to pursue a scientific career is highly dependent on the number and quality of papers you produce. In short, publications are your scientific currency. Writing papers helps your results to be confirmed or challenged by other scientists, allowing your findings to help move your field of interest forward. So how do you write a manuscript? First, prepare your paper. The most important thing to remember is the order in which other scientists will read your paper is not the same as the order in which you should prepare it. A good rule at the start of your career is to focus on writing about what you know before drawing up the introduction and summary. Materials and methods come first because writing about these should come naturally – you know this better than anyone else. Following this will be the results section. This means analyzing and deciding which data you wish to present and then formulating it into tables or graphs. You don’t have to present all the data you’ve collected in your paper. In fact, […]

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30 Nov 2022

Biomarker in urine could be the first to reveal early-stage Alzheimer’s disease

By Conn Hastings, science writer Image: BlurryMe/Shutterstock.com Alzheimer’s disease can remain undetected until it is too late to treat. Large-scale screening programs could help to detect early-stage disease, but current diagnostic methods are too cumbersome and expensive. A new study published to Frontiers is the first to identify formic acid as a sensitive urinary biomarker that can reveal early-stage Alzheimer’s disease, potentially paving the way for inexpensive and convenient disease screening.   Could a simple urine test reveal if someone has early-stage Alzheimer’s disease and could this pave the way for large-scale screening programs? A new study in Frontiers in Aging Neuroscience certainly suggests so. The researchers tested a large group of patients with Alzheimer’s disease of different levels of severity and healthy controls with normal cognition to identify differences in urinary biomarkers. They found that urinary formic acid is a sensitive marker of subjective cognitive decline that may indicate the very early stages of Alzheimer’s disease. Current methods to diagnose Alzheimer’s are expensive, inconvenient, and unsuitable for routine screening. This means that most patients only receive a diagnosis when it is too late for effective treatment. However, a non-invasive, inexpensive, and convenient urine test for formic acid could be […]

Featured news

29 Nov 2022

Philipp University of Marburg forms publishing agreement with Frontiers

Philipps University Marburg has formed an institutional membership agreement for open access publishing with Frontiers. This institutional agreement means that eligible researchers of Philipps University Marburg may benefit from 10 % membership discount. To check your eligibility, for information on how much of the APCs can be covered by the Open Access Publishing Fund or if you require any further details, please visit the libraries Open Access Publishing page or contact openaccess@ub.uni-marburg.de, a prerequisite for eligibility is that the corresponding author of the article is a member of Philipps University Marburg Philipps University of Marburg supports its researchers in making their research more widely available. This agreement will further encourage researchers of Philipps University Marburg to publish open access, increasing the volume of research openly available. While this reduces costs for the researcher, it also benefits the wider research community and the public at large.   For more information on Frontiers’ institutional agreements please visit our institutional memberships page or contact institutions@frontiersin.org to discuss the possibilities for your own organization.  Information for researchers  If you are a researcher of Philipps University Marburg, please select Philipp University Marburg in the payment information section (“Frontiers institutional members”) when submitting your article. Frontiers will verify your […]