Regulation and Mechanism of Plant Metabolites on Hyperuricemia

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ORIGINAL RESEARCH

Published on 18 Nov 2025

Puerariae lobatae Radix aqueous extract ameliorates asymptomatic hyperuricemia in a potassium oxonate-induced rat model by dual modulation of uric acid production and excretion

Danping Zhao
Yuannan Wang
Tingting He
Yingna Chen
Yu Bai
Yuchun Huang
Kaiyue Ding
Junnan Ma
Lin Zhang

doi 10.3389/fnut.2025.1685674

506 views

CLINICAL TRIAL

Published on 21 Oct 2025

Qifu Huazhuo formula for gout recurrence prevention: an interim analysis combining clinical outcomes with proteomic and metabolomic profiling

Zhengdong Shen
Fangjie Zhu
Yongliang Chu
Haiyu Wang
Maojie Wang
Xiumin Chen
Yunting Xiao
Yongqiang Yang
Runyue Huang

doi 10.3389/fphar.2025.1642121

1,518 views

ORIGINAL RESEARCH

Published on 15 Oct 2025

Aloe-emodin attenuates hyperuricemia-induced renal injury in mice by mitigating inflammation and oxidative stress

Shengfeng Wang
Quanfeng Zhu
Chengcheng Zhang
Shuang Hu
Daqun Liu
Jiawen Yu
Xiao Liu
Yan Chen
Guojun Jiang

doi 10.3389/fnut.2025.1677560

1,182 views

ORIGINAL RESEARCH

Published on 11 Dec 2024

Potential candidates from a functional food Zanthoxyli Pericarpium (Sichuan pepper) for the management of hyperuricemia: high-through virtual screening, network pharmacology and dynamics simulations

Meilin Chen
Xiaomei Chen
Qinghong Chen
Chenyang Chu
Shuxuan Yang
Chuanghai Wu
Yanting You
Andrew Hung
Angela Wei Hong Yang
4 more
Yanyan Liu

doi 10.3389/fendo.2024.1436360

2,884 views
5 citations

ORIGINAL RESEARCH

Published on 04 Dec 2024

Study on the mechanism of lactic acid bacteria and their fermentation broth in alleviating hyperuricemia based on metabolomics and gut microbiota

Lijuan Rao
Biao Dong
Yanru Chen
Jiajing Liao
Chen Wang
Guiming Fu
Yin Wan

doi 10.3389/fnut.2024.1495346

2,857 views
3 citations

ORIGINAL RESEARCH

Published on 07 Nov 2024

Association between serum carotenoids and hyperuricemia: a cross-sectional study based on NHANES 2001–2006

Pengfei Chen
Lina Miao
Lixiao Zhang
Jianpeng Du
Ming Guo
Dazhuo Shi

doi 10.3389/fnut.2024.1476031

2,051 views
3 citations

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Frontiers in Nutrition

Nutritional Epidemiology
Nutrition and Metabolism
Nutrition and Microbes

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Articles

Puerariae lobatae Radix aqueous extract ameliorates asymptomatic hyperuricemia in a potassium oxonate-induced rat model by dual modulation of uric acid production and excretion

Qifu Huazhuo formula for gout recurrence prevention: an interim analysis combining clinical outcomes with proteomic and metabolomic profiling

Aloe-emodin attenuates hyperuricemia-induced renal injury in mice by mitigating inflammation and oxidative stress

Potential candidates from a functional food Zanthoxyli Pericarpium (Sichuan pepper) for the management of hyperuricemia: high-through virtual screening, network pharmacology and dynamics simulations

Study on the mechanism of lactic acid bacteria and their fermentation broth in alleviating hyperuricemia based on metabolomics and gut microbiota

Association between serum carotenoids and hyperuricemia: a cross-sectional study based on NHANES 2001–2006

Frontiers in Nutrition

Nutritional Epidemiology

Nutrition and Metabolism

Nutrition and Microbes