Bispecific Antibodies and their Conjugates in Solid Tumors and Hematological Malignancies

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ORIGINAL RESEARCH

Published on 18 Sep 2025

Blinatumomab demonstrates MRD eradication in MRD-positive/chemotherapy-delayed pediatric B-ALL and high response in relapsed/refractory cases: a multicenter cohort study

Na Zhang
Wenting Hu
Yunpeng Dai
Jian Wang
Lijun Qu
Dan Wang
Bingju Liu
Jingbo Shao
Shuhong Shen
Hui Jiang

doi 10.3389/fimmu.2025.1607138

1,588 views

SYSTEMATIC REVIEW

Published on 10 Sep 2025

Dual-target immunotherapies in NSCLC: a systematic review and meta-analysis of randomized clinical trials

Yike Zhang
Haozhe Wang
Xinyue Yang
Changhai Lei

doi 10.3389/fimmu.2025.1605877

2,160 views

ORIGINAL RESEARCH

Published on 27 Aug 2025

Trispecific eFab-eIg T-cell engagers targeting HER2 and HER3

Ann-Kathrin Löffler
Annika Huber
Monilola A. Olayioye
Roland E. Kontermann
Oliver Seifert

doi 10.3389/fimmu.2025.1642454

2,113 views

ORIGINAL RESEARCH

Published on 12 Aug 2025

Dual T/NK cell engagement via B7-H6-targeted bispecific antibodies and IL-15 eradicates chemo-resistant solid tumors

Xuqian Ma
Huixia He
Yuankui Zhu
Dianbao Zuo
FangLin Wang
Mingqian Feng
Kangkang Ji
Xin Chen

doi 10.3389/fimmu.2025.1625813

1,885 views

REVIEW

Published on 23 Jul 2025

Blinatumomab in pediatric B-acute lymphoblastic leukemia

Yifang Cheng
Aiguo Liu

doi 10.3389/fimmu.2025.1611701

3,509 views

CORRECTION

Published on 17 Jul 2025

Correction: Bispecific antibody for lung cancer: mechanisms and clinical insights

Wei Chen
Afang Zhou
Yunfeng Zhou

doi 10.3389/fimmu.2025.1656082

551 views

ORIGINAL RESEARCH

Published on 18 Jun 2025

Characterization and functional evaluation of JS207, a novel bispecific antibody against human PD-1 and VEGFA

Shihua Lin
Min Hong
Jing Zhang
Wenting Zhao
Ke Li
Chun Wu
Qiuyun Yang
Yi Xiao
Lanqing Huang
3 more
Sheng Yao

doi 10.3389/fimmu.2025.1612547

5,755 views
1 citation

REVIEW

Published on 29 May 2025

Bispecific antibody for lung cancer: mechanisms and clinical insights

Wei Chen
Afang Zhou
Yunfeng Zhou

doi 10.3389/fimmu.2025.1572802

4,323 views

SYSTEMATIC REVIEW

Published on 25 Apr 2025

Effectiveness and safety of teclistamab for relapsed or refractory multiple myeloma: a systematic review and meta-analysis

Wenze Li
Defeng Zhao
Yu Jiao
Weilin Dong
Ziyi Wang
Xiaojing Yan

doi 10.3389/fimmu.2025.1565407

4,909 views
1 citation

MINI REVIEW

Published on 09 Apr 2025

Bispecific antibodies in immunotherapy for acute leukemia: latest updates from the 66th annual meeting of the American society of hematology, 2024

Weijie Cao
Shuhan Ma
Lijie Han
Hanzhou Xing
Yingmei Li
Zhongxing Jiang
Xuejun Guo
Jifeng Yu

doi 10.3389/fonc.2025.1566202

2,644 views
1 citation

CASE REPORT

Published on 31 Mar 2025

Successful treatment of primary refractory DLBCL/HGBL - MYC/BCL2 transformed from FL using glofitamab: a case report

Ming-qiang Chu
Ting-juan Zhang
Yuan Feng
Xun Shao
Yong-hui Ji
Jun Qian
Jing-dong Zhou

doi 10.3389/fimmu.2025.1566035

2,644 views
3 citations

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Frontiers in Oncology
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Articles

Blinatumomab demonstrates MRD eradication in MRD-positive/chemotherapy-delayed pediatric B-ALL and high response in relapsed/refractory cases: a multicenter cohort study

Dual-target immunotherapies in NSCLC: a systematic review and meta-analysis of randomized clinical trials

Trispecific eFab-eIg T-cell engagers targeting HER2 and HER3

Dual T/NK cell engagement via B7-H6-targeted bispecific antibodies and IL-15 eradicates chemo-resistant solid tumors

Blinatumomab in pediatric B-acute lymphoblastic leukemia

Correction: Bispecific antibody for lung cancer: mechanisms and clinical insights

Characterization and functional evaluation of JS207, a novel bispecific antibody against human PD-1 and VEGFA

Bispecific antibody for lung cancer: mechanisms and clinical insights

Effectiveness and safety of teclistamab for relapsed or refractory multiple myeloma: a systematic review and meta-analysis

Bispecific antibodies in immunotherapy for acute leukemia: latest updates from the 66th annual meeting of the American society of hematology, 2024

Successful treatment of primary refractory DLBCL/HGBL - MYC/BCL2 transformed from FL using glofitamab: a case report

Frontiers in Immunology

Cancer Immunity and Immunotherapy

Participating Journals

Frontiers in Oncology

Cancer Immunity and Immunotherapy