ORIGINAL RESEARCH
Published on 11 Aug 2025
Discovery of compound 1105486 as a selective inhibitor of B4GALT1: potential for pancreatic cancer therapy
doi 10.3389/fchem.2025.1651402
- 2,683 views
- Frontiers in Chemistry
- Medicinal and Pharmaceutical Chemistry
- Research Topics
- New Theories, Strategies, and Technologies for Designing Original Medicinal Molecules
New Theories, Strategies, and Technologies for Designing Original Medicinal Molecules
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ORIGINAL RESEARCH
Published on 09 Jun 2025
Integrated computational and experimental identification of N-[(1H-1,2,4-triazol-3-yl)phenyl]-1-(1H-pyrazolo[3,4-b]pyridin-3-yl)methanamide as a potent and selective TIM-3 inhibitor for NSCLC immunotherapy
doi 10.3389/fchem.2025.1622511
- 2,338 views
- 1 citation
ORIGINAL RESEARCH
Published on 22 Apr 2025
Toxicity mechanism analysis of cGAS-STING-TBK1 signaling pathway small molecule modulator based on network toxicology and molecular docking strategy: quinacrine acetate as an example
doi 10.3389/fchem.2025.1584588
- 5,169 views
- 5 citations
