Preparation of Active Components from Marine Sources and Exploration of Their Health Functions in Gut Microbiota Regulation and Lipid Metabolism

The ocean covers about 70% of the Earth's surface and is a huge resource treasure, in the context of exploring the preparation of active components from marine sources and their health functions. On the one hand, as terrestrial resources dwindle and become harder to extract, the search for new, potent substances has increasingly turned towards marine environments. Marine organisms, surviving in extreme environments like high pressure, high salinity and low temperature, have evolved substances with special physiological activities.

On the other hand, in modern society, people's health awareness increases. The increasing demand for natural health products with benefits, such as antioxidant, anti-inflammatory, antibacterial, and immune regulation effects, supports exploration into marine polysaccharides, polypeptides, and unsaturated fatty acids, showing great potential in medicine, food and cosmetics fields. Particularly, the regulation of lipid metabolism and intestinal flora by active substances derived from marine resource, including the investigation of the mechanism of action of specific marine active substances and the screening of new active substances with regulatory functions, has emerged an important scientific advancement .

Understanding the effects of marine active substances on lipid metabolism and intestinal flora can provide scientific guidance for daily dietary choice, such as increasing the intake of foods rich in specific marine active substances, which affect lipid metabolism and intestinal microenvironment, providing guidance for nutritional intervention and health management. Additionally, the goal is to advance our knowledge of mechanism behind the health effects of marine active substance, leading development of functional foods that regulate lipid metabolism and intestinal flora. This includes nutraceuticals or foods with added seaweed polysaccharides and omega-3 fatty acids, catering to demand for a healthy diet.

To advance research in this burgeoning field, contributions are invited on a variety of themes, including but not limited to:

- Extraction, separation and identification methods of marine active substances, and characterization of their chemical structure and properties.

- The regulatory effects of marine active substances on lipid metabolism, including the effects on blood lipid levels, adipocyte differentiation, lipid metabolism-related enzymes and gene expression.

- The effects of marine active substances on the intestinal flora including alteration in the structure, diversity and function of the flora, as well as the interrelationship with lipid metabolism.

- The molecular mechanism of marine active substances in regulating lipid metabolism and intestinal flora, such as signaling pathways and gene regulation.

Topic Editor Ryosuke Matsuoka is employed by Kewpie corporation and declared no competing interests with regards to the Research Topic subject.

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Article types

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Classification
• Clinical Trial
• Community Case Study
• Conceptual Analysis
• Data Report
• Editorial
• FAIR² Data
• FAIR² DATA Direct Submission
• General Commentary
• Hypothesis and Theory
• Methods
• Mini Review
• Opinion
• Original Research
• Perspective
• Policy and Practice Reviews
• Policy Brief
• Registered Report
• Review
• Systematic Review
• Technology and Code

Keywords: Bioactive Components, Marine resources, nutrition, lipid metabolism, intestinal flora

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