New Approach Methodologies in Regulatory Toxicology

192
Total downloads
3,824
Total views and downloads

Participate in this topic

Articles

ORIGINAL RESEARCH

Published on 08 Oct 2025

Reproduction of the human relevant potency threshold (HRPT) for estrogen receptor alpha agonism in an inference performance screen for ICCVAM’s regulatory scientific confidence framework

Jessica Ryman
Richard A. Becker

doi 10.3389/ftox.2025.1657708

1,028 views

ORIGINAL RESEARCH

Published on 15 Sep 2025

Error-corrected next-generation sequencing mutagenicity assays in human HepaRG cells as human-relevant genetic toxicology new approach methodology

A. Rasim Barutcu
Nimisha Bhattarai
Raymond Samuel
Jamie Scaglione
Leslie Recio

doi 10.3389/ftox.2025.1657189

949 views

ORIGINAL RESEARCH

Accepted on 10 Sep 2025

Rodent home cage monitoring for preclinical safety pharmacology assessment: results of a multi-company validation evaluating nonclinical and clinical data from three compounds

Rowland Radford Sillito
Joanne Sutherland
Aileen Milne
Chiara Giuliano
Carl-Gustav Sigfridsson
Mike Rolf
Ajeesh K Cherian
Michelle L Mcclafferty
Eric I Rossman
2 more
Anthony M Holmes

doi 10.3389/ftox.2025.1655330

542 views

Share on

Frontiers in Toxicology

Frontiers in Toxicology

Regulatory Toxicology

Manuscripts can be submitted to this Research Topic via the main journal or any other participating journal.

Impact

3,824Topic views
2,519Article views
192Article downloads