Exploring Nutrigenomics in Managing Metabolic Inflammation

Metabolic inflammation is a chronic, low-grade systemic condition that crucially impacts several major diseases, including obesity, metabolic syndrome, type 2 diabetes, nonalcoholic fatty liver disease, and cardiovascular disease. Advancements in nutrigenomic sciences have offered breakthrough insights into the pathophysiological processes that drive metabolic inflammation, suggesting the effectiveness of personalized nutritional strategies. By integrating disciplines like Nutrigenetics, Nutrigenomics, Nutriepigenetics, Nutrimetabolomics, and Metagenomics, researchers are beginning to decode the complex biological narratives between diet and gene interactions in inflammation.

This Research Topic aims to deepen the understanding of nutrigenomic applications in the personalized management of metabolic inflammation. It seeks to explore how variations in genes affect individual responses to nutrients, thus paving the way for personalized diet-based interventions to mitigate or prevent metabolic inflammation.

To ensure a comprehensive exploration of this field, the scope of this Research Topic is defined by its orientation towards both practical application and theoretical advancement in nutrigenomics. We invite contributions that cover, but are not limited to, the following themes:
• Applications of Nutrigenetics in identifying genetic predispositions related to metabolic inflammation.
• The impact of gene expression alterations in the dietary management of metabolic syndromes.
• The role of epigenetic modifications due to dietary interventions in metabolic pathways.
• Metabolomic profiling linking diet to metabolic health outcomes.
• Analysis of gut microbiota alterations through Metagenomic studies for nutrition planning.

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Clinical Trial
• Conceptual Analysis
• Data Report
• Editorial
• FAIR² Data
• FAIR² DATA Direct Submission
• General Commentary
• ... View all formats

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Article types

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Clinical Trial
• Conceptual Analysis
• Data Report
• Editorial
• FAIR² Data
• FAIR² DATA Direct Submission
• General Commentary
• Hypothesis and Theory
• Methods
• Mini Review
• Opinion
• Original Research
• Perspective
• Review
• Systematic Review
• Technology and Code

Keywords: metabolic inflammation, nutrigenomics, personalized nutrition, metabolic syndrome, obesity, type 2 diabetes, nonalcoholic fatty liver disease, cardiovascular disease, nutrigenetics, nutriepigenetics, nutrimetabolomics, metagenomics, diet-gene interactions, personalized diet interventions, gene-nutrient interaction, epigenetic modifications, metabolomic profiling, gut microbiota, genetic predispositions, nutrition planning

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.