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Original Research ARTICLE Provisionally accepted The full-text will be published soon. Notify me

Front. Psychol. | doi: 10.3389/fpsyg.2019.02147

Dimensionality and measurement invariance of the Italian version of the EORTC QLQ-C30 in postoperative lung cancer patients

 Chiara Marzorati1, 2*,  Dario Monzani1, 2,  Ketti Mazzocco1, 2, Francesca Pavan3, Massimo Monturano3 and Gabriella Pravettoni1, 2
  • 1Applied Research Division for Cognitive and Psychological Science, European Institute of Oncology, Italy
  • 2Department of Oncology and Hematology Oncology, Faculty of Medicine and Surgery, University of Milan, Italy
  • 3European Institute of Oncology (IEO), Italy

Background This study aims to validate and evaluate the psychometric properties and measurement invariance of the Italian version of the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire-Core 30 (QLQ-C30), which is a measure of Quality of Life (QoL) for lung cancer patients after surgery.
Methods 167 lung cancer patients completed the Italian version of the EORTC QLQ-C30 questionnaire at 30 days after they received a lobectomy. The factor structure of this scale was assessed by performing Confirmatory Factor Analysis (CFA). Measurement invariance was evaluated by considering differential item functioning (DIF) due to age, gender, and type of surgery (i.e., robot- or not robot-assisted).
The CFA demonstrated the validity of the factor structure of the EORTC QLQ-C30 in assessing overall health and eight distinct subscales of adverse events and functioning. Moreover, the results highlighted a minimal DIF with only trivial consequences on measurement invariance. Specifically, the DIF did not affect the mean differences of latent scores of QoL between patients undergoing robot-assisted surgery or traditional surgery.
These findings supported the validity and suitability of the EORTC QLQ-C30 for the assessment of Quality of Life in lung cancer patients of diverse ages and genders undergoing lobectomy with or without robot-assisted surgery.

Keywords: lung cancer, EORTC QLQ C-30, Quality of Life, validity, assessment, Measurement invariance

Received: 15 May 2019; Accepted: 05 Sep 2019.

Copyright: © 2019 Marzorati, Monzani, Mazzocco, Pavan, Monturano and Pravettoni. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Ms. Chiara Marzorati, Applied Research Division for Cognitive and Psychological Science, European Institute of Oncology, Milan, Italy,