In the original article, there was a calculation error underestimating the number of cancer deaths attributable to 9vHPV-targeted types.
In Table 3, the numeric values in the two rows with the subheading High-risk HPV types targeted by 9vHPV have been updated. The corrected Table 3 appears below.
Table 3
| Total | Women | Men | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Cervix | Vagina | Vulva | Anus | Oropharynx | Penis | Anus | Oropharynx | ||
| Estimated deathsa | |||||||||
| Any HPV | 7,085 | 3,812 | 308 | 868 | 677 | 182 | 223 | 388 | 628 |
| High-risk HPV types targeted by 9vHPVb | 6,482 | 3,403 | 302 | 793 | 661 | 173 | 200 | 362 | 588 |
| Estimated YPLL | |||||||||
| Any HPV | 154,954 | 100,998 | 4,405 | 12,247 | 12,548 | 3,249 | 3,377 | 7,223 | 10,905 |
| High-risk HPV types targeted by 9vHPVb | 141,019 | 90,185 | 4,311 | 11,179 | 12,249 | 3,095 | 3,036 | 6,751 | 10,212 |
| Estimated YPLL per death | 22 | 26 | 14 | 14 | 19 | 18 | 15 | 19 | 17 |
Estimated number of HPV-attributable cancer deaths in the United States in 2017 and estimated YPLL associated with HPV-attributable cancer stratified by sex and HPV type.
9vHPV, nonavalent HPV vaccine; HPV, human papillomavirus; YPLL, years of potential life lost.
HPV-attributable cancer deaths were calculated based on CDC WONDER-reported total US cancer deaths per type in 2017 (i.e., 4,207 cervical; 1,262 vulvar; 411 vaginal; 352 penile; 1,169 anal; 1,154 oropharyngeal).
HPV 16, 18, 31, 33, 45, 52, and 58.
In Table 4, the numeric values in the two rows with the subheadings HPV 16/18 and HPV 31/33/45/52/58 have been updated. The corrected Table 4 appears below.
Table 4
| PVFLP By Sex and Cancer Site (% of Total PVFLP) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Total | Women | Men | |||||||
| Cervix | Vagina | Vulva | Anus | Oropharynx | Penis | Anus | Oropharynx | ||
| Any HPV | 4,215,447 (100) | 2,847,795 (67.6) | 90,885 (2.2) | 256,211 (6.1) | 291,883 (6.9) | 73,389 (1.7) | 100,938 (2.4) | 232,742 (5.5) | 321,605 (7.6) |
| HPV 16/18 | 3,203,913 (76.0) | 2,080,839 (49.4) | 66,770 (1.6) | 180,986 (4.3) | 250,861 (6.0) | 58,896 (1.4) | 76,381 (1.8) | 207,553 (4.9) | 281,626 (6.7) |
| HPV 31/33/45/52/58 | 626,077 (14.9) | 462,059 (11.0) | 22,176 (0.5) | 52,881 (1.3) | 34,079 (0.8) | 11,014 (0.3) | 14,351 (0.3) | 9,971 (0.2) | 19,545 (0.5) |
| PVFLP per death | 595 | 747 | 295 | 295 | 431 | 404 | 453 | 600 | 512 |
Estimated present value of future lifetime productivity due to HPV-attributable cancer deaths by sex and HPV type (in thousands, 2017 $).
HPV, human papillomavirus; PVFLP, present value of future lifetime productivity.
A correction has been made to some numeric values within the abstract, results, and discussion:
Abstract Results: “An estimated 7,085 HPV-attributable cancer deaths occurred in 2017 accounting for 154,954 YPLL, with 6,482 deaths (91%) and 141,019 YPLL (91%) attributable to 9vHPV-targeted types. The estimated PVFLP was $3.8 billion for cancer deaths attributable to 9vHPV-targeted types (84% from women). The highest productivity burden was associated with cervical cancer in women and anal and oropharyngeal cancers in men.”
Results sentence 1: “This analysis estimated that a total of 7,085 HPV-attributable cancer deaths occurred in the United States in 2017; of these, 6,482 (91%) deaths were attributable to the high-risk types targeted by 9vHPV (i.e., HPV 16, 18, 31, 33, 45, 52, and 58; Table 3).”
Results paragraph 3: “The estimated PVFLP for cancer deaths due to HPV 16/18 and HPV 31/33/45/52/58 were $3.2 billion (76%) and $626 million (15%), respectively. The average PVFLP per death among men and women were $529,248 and $608,906, respectively.”
Discussion paragraph 8: “Cancer deaths caused by high-risk 9vHPV-targeted types accounted for 91% of the total YPLL and total PVFLP.”
In the original article, there was a mistake in the discussion that has been corrected:
Discussion paragraph 10: “However, the statement also acknowledged the non-labor-market value of women who are raising children, caring for their families, and contributing to the social and economic fabric of their communities, a burden that is captured in our analysis but also needs to be evaluated in future studies.”
The authors apologize for the errors and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
Publisher's Note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.
Summary
Keywords
human papillomavirus, productivity loss, mortality, cervical cancer, oropharyngeal cancer
Citation
Priyadarshini M, Prabhu VS, Snedecor SJ, Corman S, Kuter BJ, Nwankwo C, Chirovsky D and Myers E (2021) Corrigendum: Economic Value of Lost Productivity Attributable to Human Papillomavirus Cancer Mortality in the United States. Front. Public Health 9:691634. doi: 10.3389/fpubh.2021.691634
Received
06 April 2021
Accepted
25 June 2021
Published
26 July 2021
Volume
9 - 2021
Edited and reviewed by
Olatunde Aremu, Birmingham City University, United Kingdom
Updates
Copyright
© 2021 Priyadarshini, Prabhu, Snedecor, Corman, Kuter, Nwankwo, Chirovsky and Myers.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Vimalanand S. Prabhu vimalanand.prabhu@merck.com
This article was submitted to Health Economics, a section of the journal Frontiers in Public Health
Disclaimer
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.