Frontiers in Aging Neuroscience

Original Research

Published on 25 Sep 2025

Early-life hearing loss induces persistent cognitive deficits: evidence from human data and a mouse model with environmental intervention

Xuehua Zhou
Huiqian Yu
Yiru Wang
Kaizheng Chen
Xia Shen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1662732

2,047 views

Review

Published on 25 Sep 2025

Current aspects of targeting cellular senescence for the therapy of neurodegenerative diseases

Ravindran Jaganathan
Ashok Iyaswamy
Senthilkumar Krishnamoorthi
Abhimanyu Thakur
Siva Sundara Kumar Durairajan
Chuanbin Yang
Dapkupar Wankhar

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1627921

4,704 views
3 citations

Methods

Published on 25 Sep 2025

Current application status of non-invasive brain stimulation techniques in Alzheimer’s disease: a bibliometric analysis

Shan Cong
Meng Wang
Long Yan
Li Sun
Bowen Zheng
Jinying Xie
Tao Yu
Yulin Qian

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1585885

3,411 views
1 citation

Correction

Published on 25 Sep 2025

Correction: Altered dynamic functional network connectivity patterns in Alzheimer's disease: insights into neural dysfunction

Xuerui Pang
Yi Ji
Chenyang Hu
Yulong Dai
Panpan Hu
Xingqi Wu
Kai Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1693649

1,323 views

Original Research

Published on 25 Sep 2025

Risk factor analysis of cognitive frailty in older adults with type 2 diabetes mellitus: a cross-sectional study

Qingjuan Ren
Shu Niu
Lei Zhi
Hongfang Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1667405

2,649 views
1 citation

Opinion

Published on 24 Sep 2025

Regulatory mechanisms of neuro inflammation from a gender perspective: interactions among astrocytes, sex hormones, and the gut-brain axis

Jia-Wei Shi
Xiu-Li Meng
Yu Ye
Yi-Ting Wang
He-Xuan Ding
Wen-Xu Qi
Rui Feng
Ke Zhang
Ming Lei

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1675694

2,454 views

Systematic Review

Published on 24 Sep 2025

Unveiling the glymphatic system’s impact on neurodegenerative diseases: a comprehensive bibliometric analysis (2012–2024)

Younian Wang
Qiangsheng Liu
Junyi Wu
Kun Meng
Lanting Zhou
Fan Ye

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1598608

4,881 views
3 citations

Original Research

Published on 24 Sep 2025

Regional high iron deposition is linked with cognitive impairments in peritoneal dialysis: a quantitative susceptibility mapping study

Dashan Li
Yongjie Yin
Shan Jiang
Jiuyu Yin
Luyao Yu
Nan Feng
Zhaohua Sun
Zilian Chen
Hongting Xu
Yu Zhou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1660734

2,322 views

Original Research

Published on 24 Sep 2025

Latent profiles and correlates factors of cognitive function in older adults: a cross-sectional study

Jin Xiang
Yan Xiong
Heting Liang
Qingyun Mao
Yumeng Zhang
Yunting Li
Zhixia Jiang
Xiaoli Yuan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1622804

2,697 views

Original Research

Published on 23 Sep 2025

The impact of ondansetron on clinical outcomes in cranial surgery patients: a propensity-matched analysis of retrospective data

Debo Yun
Yongzhen Luo
Rui Li
Wenyong Li
Chunyou Wan
Qinjiang Huang
Jiang Du
Shiyi Zeng
Guangdong Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1627353

2,441 views

Original Research

Published on 23 Sep 2025

Music elicits different gene expression responses in the buccal cavity of age-related cognitive disorders patients and healthy controls

Alberto Gómez-Carballa
Laura Navarro
Nour El Zahraa Mallah
Xabier Bello
Sara Pischedda
Sandra Viz-Lasheras
María José Currás
Isabel Ferreirós-Vidal
Narmeen Mallah
Julián Montoto-Louzao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1622816

3,260 views
2 citations

Original Research

Published on 23 Sep 2025

Development and validation of a prognostic scoring system for cognitive decline in adults aged 50 and older in China

Ningjie Zhang
Linglei Meng
Zhendong Qian
Ying Jin
Hua Yan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1664943

2,435 views

Original Research

Published on 23 Sep 2025

Quantitative analysis of serum metabolites in a rat model of Alzheimer’s disease

Anton A. Smolentsev
Darya V. Telegina
Nataliya G. Kolosova
Yuri P. Tsentalovich
Olga A. Snytnikova

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1648561

2,734 views

Original Research

Published on 22 Sep 2025

Regional CSF volume quantification using deep learning for comparative analysis of brain atrophy in frontotemporal dementia subtypes

Kyoung Yoon Lim
Soyeon Yoon
Seongbeom Park
Seongmi Kim
Kyoungmin Kim
Jehyun Ahn
Jun Pyo Kim
Hee Jin Kim
Duk L. Na
Sang Won Seo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1631640

2,505 views

Review

Published on 19 Sep 2025

STING-mediated neuroinflammation: a therapeutic target in neurodegenerative diseases

Haoqin Zhang
Ziyang He
Can Yin
Shiyi Yang
Jianqiao Li
Hong Lin
Guishan Hu
Anguo Wu
Dalian Qin
Guangqiang Hu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1659216

5,707 views
4 citations

Systematic Review

Published on 19 Sep 2025

Association of brain-derived neurotrophic factor in blood and cerebrospinal fluid with Parkinson’s disease and non-motor symptoms of Parkinson’s disease: a systematic review and meta-analysis of 6655 participants

Zhenzhen Zhao
Jiahui Sun
Youhong Liu
Miao Liu
Di Tong

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1620172

3,711 views
2 citations

Brief Research Report

Published on 18 Sep 2025

Beyond traditional proxies: the contribution of leisure to cognitive reserve and dementia

Silvia Ottaviani
Luca Tagliafico
Stefania Peruzzo
Marta Ponzano
Alessio Signori
Alessio Nencioni
Fiammetta Monacelli

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1600798

3,000 views

Original Research

Published on 18 Sep 2025

Association between cardiovascular disease risk, regional brain age gap, and cognition in healthy adults

Sriya Pallapothu
Roger D. Newman-Norlund
Nicholas Riccardi
Raghav Pallapothu
Pranesh Rajesh Kannan
Leonardo Bonilha
Julius Fridriksson
Chris Rorden

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1611847

3,327 views

Review

Published on 18 Sep 2025

Understanding Parkinson’s disease: current trends and its multifaceted complications

Sameer A. Chaudhary
Sapana Chaudhary
Sakshi Rawat

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1617106

9,278 views
3 citations

Original Research

Published on 18 Sep 2025

Global burden of Alzheimer’s disease and other dementias (1990–2021): inequality, frontier, and decomposition analysis

Haishou Fu
Huaqing Huang
Shuzhen Liao
Zhisen Dai

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1637029

4,500 views

Original Research

Published on 17 Sep 2025

Moderating effect of APOE ε4 on the association of sleep disturbance and amyloid-β pathology among cognitively normal older adults

Shufei Feng
Jianyu Que
Qianwen Wang
Kai Yuan
Le Shi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1627774

3,066 views

Systematic Review

Published on 17 Sep 2025

The effects of Nordic walking on cognitive function in older adults: a systematic review and meta-analysis

Haobai Li
Ke Zhu
Jianyu Gan
Ziyi Wang
Zhikun Gao
Liangru Liu
Xiaojie Guo
Jianfeng Niu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1666449

3,445 views

Clinical Trial

Published on 16 Sep 2025

Effects of exercise-cognitive dual-task training on cognitive frailty in older adults: a randomized controlled trial

Xiaoxing Lai
Hongwei Zhu
Yonghua Cai
Baoyu Chen
Yang Li
Hongdi Du
Liping Zhang
Wenwen Wang
Shuxian Li
Xiaopeng Huo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1639245

5,322 views
2 citations

Review

Published on 16 Sep 2025

Exercise-mediated cerebrovascular repair in Alzheimer's disease: from pathophysiology to therapeutic precision

Ming Cai
Keren Cai
Ziqi Wei
Jing Zhou
Jiayi Shu
Weiyi Wang
Wanju Sun
Jingyun Hu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1632365

3,743 views

7,812 Publications

volumes

Volume 17 - 2025

Early-life hearing loss induces persistent cognitive deficits: evidence from human data and a mouse model with environmental intervention

Current aspects of targeting cellular senescence for the therapy of neurodegenerative diseases

Current application status of non-invasive brain stimulation techniques in Alzheimer’s disease: a bibliometric analysis

Correction: Altered dynamic functional network connectivity patterns in Alzheimer's disease: insights into neural dysfunction

Risk factor analysis of cognitive frailty in older adults with type 2 diabetes mellitus: a cross-sectional study

Regulatory mechanisms of neuro inflammation from a gender perspective: interactions among astrocytes, sex hormones, and the gut-brain axis

Unveiling the glymphatic system’s impact on neurodegenerative diseases: a comprehensive bibliometric analysis (2012–2024)

Regional high iron deposition is linked with cognitive impairments in peritoneal dialysis: a quantitative susceptibility mapping study

Latent profiles and correlates factors of cognitive function in older adults: a cross-sectional study

The impact of ondansetron on clinical outcomes in cranial surgery patients: a propensity-matched analysis of retrospective data

Music elicits different gene expression responses in the buccal cavity of age-related cognitive disorders patients and healthy controls

Development and validation of a prognostic scoring system for cognitive decline in adults aged 50 and older in China

Quantitative analysis of serum metabolites in a rat model of Alzheimer’s disease

Regional CSF volume quantification using deep learning for comparative analysis of brain atrophy in frontotemporal dementia subtypes

STING-mediated neuroinflammation: a therapeutic target in neurodegenerative diseases

Association of brain-derived neurotrophic factor in blood and cerebrospinal fluid with Parkinson’s disease and non-motor symptoms of Parkinson’s disease: a systematic review and meta-analysis of 6655 participants

Beyond traditional proxies: the contribution of leisure to cognitive reserve and dementia

Association between cardiovascular disease risk, regional brain age gap, and cognition in healthy adults

Understanding Parkinson’s disease: current trends and its multifaceted complications

Global burden of Alzheimer’s disease and other dementias (1990–2021): inequality, frontier, and decomposition analysis

Moderating effect of APOE ε4 on the association of sleep disturbance and amyloid-β pathology among cognitively normal older adults

The effects of Nordic walking on cognitive function in older adults: a systematic review and meta-analysis

Effects of exercise-cognitive dual-task training on cognitive frailty in older adults: a randomized controlled trial

Exercise-mediated cerebrovascular repair in Alzheimer's disease: from pathophysiology to therapeutic precision