Frontiers in Bioengineering and Biotechnology

Original Research

Published on 17 Oct 2025

Polydopamine nanoparticles as immunomodulators: inhibition of M1 microglial polarization

in Nanobiotechnology

Maria Cristina Ceccarelli
Luigi Lai
Alessio Carmignani
Matteo Battaglini
Gianni Ciofani

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1672520

2,084 views
1 citation

Original Research

Published on 17 Oct 2025

Implementation of the sensory organization test with the CAREN system: a pilot study

in Biomechanics

Paolo De Pasquale
Augusto Ielo
Cristiano De Marchis
Daniele Borzelli
Antonino Casile
Antonio Caronni
Stefano Scarano
Rocco Salvatore Calabrò
Luigi Tesio
Angelo Quartarone

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1635514

1,647 views

Original Research

Published on 17 Oct 2025

A multimodal microfluidic-based platform integrating topographical and equibiaxial mechanical cues for next-generation in vitro cell microenvironment mimicking

in Biofabrication

Denise Pagliara
Raffaele Vecchione
Valentina Mollo
Paolo Antonio Netti

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1657107

1,834 views

Original Research

Published on 17 Oct 2025

A multifunctional bilayer wound dressing co-loaded with nanosilver and bFGF for enhanced skin regeneration: synergistic antibacterial, hemostatic, and angiogenic effects

in Tissue Engineering and Regenerative Medicine

Qianqian Wang
Fang Ma
Ying Xian
Xingyan Shi
Shenglan Ma
Rui Zhang
Hualin Zhang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1650545

1,631 views

Review

Published on 16 Oct 2025

Photobiomodulation in fibroblasts: from light to healing through molecular pathways, omics and artificial intelligence

in Tissue Engineering and Regenerative Medicine

Sarassunta Ucci
Eugenio Caradonna
Anna Aliberti
Andrea Cusano

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1675619

3,902 views
3 citations

Systematic Review

Published on 16 Oct 2025

Effectiveness of AI-assisted rehabilitation for musculoskeletal disorders: a network meta-analysis of pain, range of motion, and functional outcomes

in Biomechanics

Zixuan Luo
Yang Wang
Tongyan Zhang
Jiale Wang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1660524

5,007 views
4 citations

Review

Published on 16 Oct 2025

Bioscaffold materials resist infection and promote bone defect repair by regulating neutrophil function

in Tissue Engineering and Regenerative Medicine

Jingyu Zhou
Shilang Xiong
Shiwei Liu
Zhigang Zhou
Min Liu
Hanrui Xi
Weihao Kong
Jianguo Zhou
Long Xiong

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1644625

2,223 views

Review

Published on 16 Oct 2025

Human induced pluripotent stem cell-derived cardiomyocytes for disease modeling and drug discovery

in Tissue Engineering and Regenerative Medicine

Taijun Moriwaki
Hidenori Tani
Shugo Tohyama

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1687840

3,704 views

Original Research

Published on 15 Oct 2025

Production of high-affinity glycosylated anti-mouse conjugated nanobodies in Pichia pastoris

in Bioprocess Engineering

Sofía Orioli
Javier Santos
Lorena I. Ibañez
Cecilia D’Alessio

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1673481

2,444 views

Original Research

Published on 15 Oct 2025

Artificial cell vesicle-mediated delivery of Catharanthus roseus (L.) G. Don-derived vinca alkaloids for enhanced antitumor efficacy

in Biomaterials

Xiaodong Zhuang
Liangjiu Huang
Risheng Liu
Liwen Guan
Xingyue Fang
Ting Ma

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1703637

1,777 views

Original Research

Published on 15 Oct 2025

The influence of sex on lower limb biomechanical characteristics during single-leg drop landing in individuals with unilateral functional ankle instability

in Biomechanics

Huizi Cui
Zilong Wang
Minjie Lin
Tao Liu
Xiangdong Wang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1703251

1,778 views

Original Research

Published on 15 Oct 2025

Construction of bioactive nanocomposites from beta-sitosterol, fucoidan, chitosan, and silver nanoparticles for anticancer applications

in Nanobiotechnology

Ahmed A. Tayel
Fatma K. Elagezy
Asmaa Abdella
Hend A. Gad
Mohamed E. El-Hefnawy
Sultan Alhayyani
Shaymaa W. El-Far

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1668888

1,741 views

Original Research

Published on 15 Oct 2025

Development and in-vitro validation of an intraoral wearable biofeedback system for bruxism management

in Biosensors and Biomolecular Electronics

Khalid A. Al-Hamad
Ashwaq Asiri
Ali M. Al-Qahtani
Saud Alotaibi
Abdullah Almalki

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1572970

2,489 views

Review

Published on 15 Oct 2025

Fibroblasts as key cellular targets in acupuncture therapy: a mechanistic perspective

in Biomechanics

Shi-Wei Tu
Jun Kawanokuchi
Ken Takagi
Yang-Yang Liu
Yan-Wei Li
Jun-Yi Li
Jia-Yi Tu
Ning Ma
Yi Guo

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1662525

3,967 views

Original Research

Published on 15 Oct 2025

Automated detection of pinworm parasite eggs using YOLO convolutional block attention module for enhanced microscopic image analysis

in Biosensors and Biomolecular Electronics

Esraa Hassan
Felwah Alqahtani
Samar Elbedwehy
Amira Samy Talaat

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1559987

2,596 views

Original Research

Published on 14 Oct 2025

Biomechanical design of titanium-PEEK combined fusion cage based on PLIF surgical model

in Biomechanics

Chunsheng Liu
Yutang Xie
Xinrui Wu
Yanqin Wang
Yanru Xue
Pengcui Li
Wangping Duan
Xiaochun Wei
Weiyi Chen
Jinzhu Yin

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1671068

2,177 views

Original Research

Published on 14 Oct 2025

The inclination of the tibial component has an impact on fracture stability in unicompartmental knee arthroplasty: an artificial bone study

in Biomechanics

Mathis Wegner
Maximilian Bettendorff
Malte Bruhn
Jörg Bahr
Jürgen Carstensen
Leonard Siebert
Babak Moradi

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1615216

1,582 views

Review

Published on 13 Oct 2025

Protein-based micro- and nano-transporters for gut microbiota modulators: advances in delivery strategies and gut health benefits

in Nanobiotechnology

Mohammad Nasiruddin Rana
Md. Saifullah
Abu Saeid
Md. Murtuza Kamal
Xiangjing Gao
Xiangwei Gao

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1706245

2,877 views
1 citation

Original Research

Published on 13 Oct 2025

Retinal features as predictive indicators for high myopia: insights from explainable multi-machine learning models

in Biomechanics

Haohan Zou
Jing Liu
Shenda Shi
Saiguang Ling
Qian Fan
Yan Huo
Zhou Dong
Guoge Han
Shengjin Wang
Yan Wang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1609639

2,035 views
1 citation

Editorial

Published on 13 Oct 2025

Editorial: Biomacromolecule systems for enhanced therapeutic delivery in medical implants

in Biomaterials

Joao Henrique Lopes
Nicolas Tabary
Jacobo Hernandez-Montelongo

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1700914

1,240 views

Original Research

Published on 13 Oct 2025

Joint modeling and marker set selection significantly influence functional biomechanics in end-stage knee osteoarthritis: evidence from the sit-to-stand task

in Biomechanics

Giovanni Spallone
Letizia Mancini
Arianna Carnevale
Stefano Campi
Emiliano Schena
Pieter D’Hooghe
Michael T. Hirschmann
Rocco Papalia
Umile Giuseppe Longo

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1677244

2,158 views

Original Research

Published on 13 Oct 2025

Targeted UDP-glucose ceramide glucosyltransferase stable overexpression induces a metabolic switch improving cell performance at high cell density

in Synthetic Biology

Marzia Rahimi
Lars K. Nielsen
Jesús Lavado-García

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1690203

2,233 views

Original Research

Published on 13 Oct 2025

FieldNA: a 3D printed vertical microfluidic device for portable nucleic acid isolation from olive oil samples

in Biosensors and Biomolecular Electronics

Vineet Penumarthy
Athanasia-Maria Dourou
Evangelia Lampropoulou
Stilianos Arhondakis
Ravi Prakash

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1646041

2,022 views

Original Research

Published on 10 Oct 2025

Optimising tibial extension stem selection in total knee arthroplasty: the role of digital modelling

in Biomechanics

Mathieu Severyns
François Zot
Marc Gardegaront
Arnaud Germaneau
Tanguy Vendeuvre

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1634172

1,640 views