Frontiers in Cell and Developmental Biology | Molecular and Cellular Pathology

Original Research

Accepted on 26 May 2025

Revealing age-related changes in the intraocular microenvironment and senescence modulators based on aqueous humor proteomics via machine learning

in Molecular and Cellular Pathology

Sheng Xiao Huang
Tiansheng Chou
Xinhua Liu
Kun Zeng
Liangnan Sun
Zonghui Yan
Shaoyi Mei
Wenqun Xi
Zongyi Zhan
Yi Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1583330

123 views

Review

Accepted on 26 May 2025

Immune dysregulation in ulcerative colitis: Pathogenic mechanisms and therapeutic strategies of traditional Chinese medicine

in Molecular and Cellular Pathology

Xudong Tang
Yilin Huang
Ying Zhu
Yin Xu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1610435

147 views

Original Research

Accepted on 26 May 2025

17β-Estradiol maintains extracellular matrix homeostasis of nucleus pulposus cells by activating p70 S6K1 signaling pathway

in Molecular and Cellular Pathology

Tao Liu
Zhaohui Li
Wei Zhang
Xuzhao Guo
Sidong Yang
Dalong Yang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1564458

129 views

Review

Accepted on 26 May 2025

Genetic landscape of phospholamban cardiomyopathies

in Molecular and Cellular Pathology

Elizabeth Vafiadaki
Ishita Chaudhari
Keisha Mireia Soliman
ARISTIDES G. ELIOPOULOS
Evangelia G Kranias
Despina Sanoudou

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1626242

112 views

Original Research

Published on 26 May 2025

Early detection of retinal and choroidal microvascular impairments in diabetic patients with myopia

in Molecular and Cellular Pathology

Yufei Wu
Jiahui Jiang
Xiaoyu Deng
Xixi Zhang
Jinger Lu
Zian Xu
Yitian Zhao
Zai-Long Chi
Qinkang Lu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1609928

420 views

Review

Accepted on 23 May 2025

Large language models in the management of chronic ocular diseases： A scoping review

in Molecular and Cellular Pathology

Ting Fan
Jia-tong Zhang
Xiao-Xi Song
Bo-cheng Tian
Ming-Ke Tian
Zhi-chang Zhang
Jing Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1608988

139 views

Original Research

Published on 23 May 2025

Large language model-based multimodal system for detecting and grading ocular surface diseases from smartphone images

in Molecular and Cellular Pathology

Zhongwen Li
Zhouqian Wang
Liheng Xiu
Pengyao Zhang
Wenfang Wang
Yangyang Wang
Gang Chen
Weihua Yang
Wei Chen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1600202

519 views

Original Research

Published on 22 May 2025

snRNA-seq reveals subcutaneous white adipose tissue remodeling upon return to thermoneutrality after cold stimulation

in Molecular and Cellular Pathology

Yusha Yang
Guanyu Zhang
Ting Yi
Shuran Yang
Shuai Wu
Yongqiang Zhang
Li Zhang
Xi Li
Xiuxuan Wu
Jun Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1578180

529 views

Original Research

Published on 22 May 2025

Machine learning-driven prediction of cycloplegic refractive error in Chinese children

in Molecular and Cellular Pathology

Bichi Chen
Li Tian
Fuyue Tian
Qiaochu Yang
Ying Ruan
Ying Li
Min Cao
Chuanyan Wu
Maoyuan Yang
Suzhong Xu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1608494

392 views

Original Research

Published on 22 May 2025

Integration of machine learning and bulk sequencing revealed exosome-related gene FOSB was involved in the progression of abdominal aortic aneurysm

in Molecular and Cellular Pathology

Xianlu Ma
Hongjie Zhou
Ren Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1554972

322 views

Original Research

Published on 22 May 2025

Cell-based high-content approach for SARS-CoV-2 neutralization identifies unique monoclonal antibodies and PI3K pathway inhibitors

in Molecular and Cellular Pathology

Carly R. Cabel
Briana A. Guzman
Elaheh Alizadeh
Shuaizhi Li
Cameron Holberg
Chonlarat Wichaidit
Darren A. Cusanovich
Andrew L. Paek
Gregory R. J. Thatcher
Koenraad Van Doorslaer

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1538934

645 views

Original Research

Published on 21 May 2025

Based on TransRes-Pix2Pix network to generate the OBL image during SMILE surgery

in Molecular and Cellular Pathology

Zeyu Zhu
Peifen Lin
Lingling Zhong
Qing Wang
Jingjing Xu
Kang Yu
Zheliang Guo
Yicheng Xu
Taorong Qiu
Yifeng Yu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1598475

412 views

Correction

Published on 21 May 2025

Corrigendum: A novel variant in CLCN7 regulates the coupling of angiogenesis and osteogenesis

in Molecular and Cellular Pathology

Hui Peng
Hong-Bo He
Ting Wen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1616778

262 views

Review

Published on 20 May 2025

“Proteinjury”: a universal pathological mechanism mediated by cerebrospinal fluid in neurodegeneration and trauma

in Molecular and Cellular Pathology

Vladimir F. Lazarev
Bashar A. Alhasan
Irina V. Guzhova
Boris A. Margulis

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1593122

875 views

Opinion

Published on 20 May 2025

Generalized arteriomegaly as a precursor to multifocal aneurysmal disease: implications for early intervention

in Molecular and Cellular Pathology

Zhaohua Cai
Ben He

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1592225

273 views

Original Research

Accepted on 19 May 2025

Deep Learning System for the Auxiliary Diagnosis of Thyroid Eye Disease: Evaluation of Ocular Inflammation, Eyelid Retraction, and Eye Movement Disorder

in Molecular and Cellular Pathology

Yu Han
Jun Xie
Xiaoyu Li
Xinying Xu
Bin Sun
Liu Han
Chunfang Yan

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1609231

240 views