In the original article, there was a mistake in the legend for Figure 1 as published. The figure was not reprinted from (Hauge et al., ) but from (Horsman et al., ). The corrected legend appears below.
Figure 1. Schematic representation of tumor cells distribution under chronic (A) and acute (B) hypoxia. In a diffusion-limited chronic hypoxia condition (A) the oxygen molecules diffusing from the vessels are used by normoxic cells which result in a decrease of pO2(C). The reduced level of molecular oxygen triggers the proliferation of hypoxic cells at the periphery of the blood vessels. When the vessels are functionally compromised, all the cells around the capillary become acutely hypoxic. Representative flows of pO2 over time in the occluded region are shown for comparison (D). Adapted with permission from Horsman et al. ().
Additionally, there was a small mistake in Figure 6 as there is a missing a methylene group. The corrected Figure 6 appears below.
Figure 6
In the original manuscript there was one error in Horsman et al. () reference. The title read “Imaging hypoxia to improve radiotherapy outcome” and has now been corrected. Also page number range should be 674–687. The corrected wording for these references appear in the Reference List.
The authors apologize for these errors and state that this does not change the scientific conclusions of the article in any way.
The original article has been updated.
Statements
Conflict of interest
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
References
1
HaugeA.WegnerC. S.GaustadJ.-V.SimonsenT. G.AndersenL. M. K.RofstadE. K. (2017). DCE-MRI of patient-derived xenograft models of uterine cervix carcinoma: associations with parameters of the tumor microenvironment. J. Trans. Med.15:225. 10.1186/s12967-017-1331-4
2
HorsmanM. R.MortensenL. S.PetersenJ. B.BuskM.OvergaardJ. (2012). Imaging hypoxia to improve radiotherapy outcome. Nat. Rev. Clin. Oncol.9, 674–687. 10.1038/nrclinonc.2012.171
3
KomatsuH.ShindoY.OkaK.HillJ. P.ArigaK. (2014). Ubiquinone-Rhodol (UQ-Rh) for fluorescence imaging of NAD(P)H through intracellular activation. Angew. Chem. Int. Ed.53, 3993–3995. 10.1002/anie.201311192
Summary
Keywords
oxygen sensing, molecular imaging, hypoxia, metals in medicine, FRET
Citation
Mirabello V, Cortezon-Tamarit F and Pascu SI (2018) Corrigendum: Oxygen Sensing, Hypoxia Tracing and in Vivo Imaging with Functional Metalloprobes for the Early Detection of Non-communicable Diseases. Front. Chem. 6:512. doi: 10.3389/fchem.2018.00512
Received
01 October 2018
Accepted
04 October 2018
Published
23 October 2018
Volume
6 - 2018
Edited and reviewed by
Simone Brogi, Università degli Studi di Siena, Italy
Updates
Copyright
© 2018 Mirabello, Cortezon-Tamarit and Pascu.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Vincenzo Mirabello v.mirabello@bath.ac.ukFernando Cortezon-Tamarit f.c.cortezon.tamarit@bath.ac.ukSofia I. Pascu s.pascu@bath.ac.uk
This article was submitted to Medicinal and Pharmaceutical Chemistry, a section of the journal Frontiers in Chemistry
†These authors have contributed equally to this work
Disclaimer
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