Frontiers in Endocrinology | Pediatric Endocrinology

Original Research

Published on 18 Nov 2025

Exosomal miRNAs as potential biomarkers for insulin resistance and metabolic dysfunction-associated steatotic liver disease in children with obesity

in Pediatric Endocrinology

Eu-Seon Noh
Yoonseo Yeum
Hye Young Jin
Seongho Ryu
Il Tae Hwang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1683403

1,344 views

Editorial

Published on 17 Nov 2025

Editorial: Perinatal and post-natal life: metabolism and health outcomes

in Pediatric Endocrinology

Ana Paula Santos-Silva
Cintia R. Pinheiro
Natalia da Silva Lima

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1736688

653 views

Original Research

Published on 11 Nov 2025

Bile acids: potential links to overweight/obesity and androgen levels in pubertal girls

in Pediatric Endocrinology

Sofia Malave-Ortiz
Samantha A. M. McNeley
Sheri Denslow
Fred B. Lih
Natalie D. Shaw

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1695465

1,429 views

Original Research

Published on 06 Nov 2025

Metabolic factors influencing the efficacy of recombinant human growth hormone therapy in children with short stature

in Pediatric Endocrinology

Xueyu Zhong
Yang Chen
Geng Liu
Zhenhai Cui
Kuanhong Luo
Zhixin Wu
Kangli Xiao
Huiqing Li

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1691509

1,725 views

Original Research

Published on 31 Oct 2025

PNPLA3-Ile148Met and TM6SF2-Glu167Lys increase susceptibility to metabolic dysfunction-associated steatotic liver disease in children

in Pediatric Endocrinology

Hengpan Yao
Zhiyi Xia
Yijing Liu
MengJun Dong
Kairui Yang
Fang Zhou

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1689656

1,469 views

Review

Published on 29 Oct 2025

Pharmacological and non-pharmacological modulation of endoplasmic reticulum stress in pediatric diabetes

in Pediatric Endocrinology

Aristeidis P. Giannakopoulos

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1690478

1,186 views

Original Research

Published on 23 Oct 2025

Food responsiveness, addiction, and hyperphagia in Prader-Willi syndrome: a cross-sectional study of 210 Chinese patients

in Pediatric Endocrinology

Chen-Xi Hu
Fang-ling Xia
Yi-Fang Qin
Yun-Qi Chao
Yu-Lu Ruan
Jing-Wen Li
Guan-Ping Dong
Chao-Chun Zou

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1665040

1,948 views

Original Research

Published on 21 Oct 2025

Growth hormone therapy and chromosomal mosaicism in turner syndrome: 25 years of growth outcomes in Taiwan

in Pediatric Endocrinology

Yu-Ting Chang
Ying-Hua Huang
Fu-Sung Lo

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1640414

2,498 views

Editorial

Published on 17 Oct 2025

Editorial: Interplay of genetics and environment in pediatric diabetes: insights and innovations

in Pediatric Endocrinology

Tiago Jeronimo Dos Santos
Marina Ybarra
Rade Vukovic
Agata Chobot

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1720343

1,032 views

Case Report

Published on 17 Oct 2025

First description of co-occurrence of 49,XXXXY and X-linked Cornelia de Lange syndrome: case report

in Pediatric Endocrinology

Sumaiya Al-Rashdi
Lori Ekstrom
Aedin Collins
Heidi L. Schulz
April Dinwiddie
Carole Samango-Sprouse
Margaret Olaya
Elizabeth Moser
Andrew J. Green

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1688852

3,682 views

Original Research

Published on 16 Oct 2025

Comprehensive characterization of 21-hydroxylase deficiency in a Chinese pediatric cohort: phenotype, steroid profiles and genetics

in Pediatric Endocrinology

Hemeng Chong
Guocui Xue
Yalei Pi
Yanan Zhang
Yuqian Li
Yutong Xing
Baorong Chen
Huifeng Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1665306

1,651 views

Original Research

Published on 15 Oct 2025

Differences in growth in prepubertal children with definite growth hormone deficiency, short stature unresponsive to stimulation tests, and idiopathic short stature treated with recombinant human growth hormone: a retrospective study

in Pediatric Endocrinology

Gianluca Tamaro
Maria Andrea Lanzetta
Martin Ove Carlsson
Daria La Torre
Gianluca Tornese

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1628072

2,773 views

Original Research

Published on 15 Oct 2025

The role of digital health in growth hormone therapy: perspectives from Gulf Cooperation Council pediatric endocrinologists

in Pediatric Endocrinology

Walid Kaplan
Abdullah Alherbish
Abdullah Aljnaibi
Afaf Alsagheir
Angham Almutair
Aqeel Farooque
Asma Deeb
Bassam Bin Abbas
Jamal Al Jubeh
Najya Attia

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1641513

1,866 views

Case Report

Published on 15 Oct 2025

Case Report: Autoimmune polyglandular syndrome type 4 involving diabetes mellitus type 1, autoimmune hepatitis, immune thrombocytopenia, and celiac disease

in Pediatric Endocrinology

Miłosz Nesterowicz
Katarzyna Anikiej
Hanna Borysewicz-Sańczyk
Aneta Zasim
Stanisław Trzebuchowski
Katarzyna Bąbol-Pokora
Dariusz Lebensztejn
Elżbieta Leszczyńska
Artur Bossowski

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1655483

3,027 views

Original Research

Published on 09 Oct 2025

Utility of continuous glucose monitoring for identifying silent hypoglycemia in fructose-1,6-bisphosphatase deficiency: a pilot prospective evaluation

in Pediatric Endocrinology

Emine Goksoy
Burcu Kumru Akin

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1664863

1,486 views

Systematic Review

Published on 07 Oct 2025

Efficacy of combined gonadotropin-releasing hormone analogue and growth hormone therapy in girls with central precocious puberty: a systematic review and meta-analysis

in Pediatric Endocrinology

Sufeng Jin
Yanhong Sun
Zhouyue Zhu
Haitao Yu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1662808

3,200 views

Original Research

Published on 07 Oct 2025

Brain structural changes in girls with idiopathic central precocious puberty: a voxel-based morphometry and surface-based morphometry analysis

in Pediatric Endocrinology

Yun Zhang
Lu Tian
Xiaojian Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1643660

1,676 views

Review

Published on 01 Oct 2025

Insulin resistance, metabolic syndrome and polycystic ovaries: an intriguing conundrum

in Pediatric Endocrinology

Sara Prosperi
Francesco Chiarelli

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1669716

8,001 views
5 citations

Original Research

Published on 25 Sep 2025

U-shaped association between triglyceride-glucose index and acute kidney injury in critically ill children with cardiac diseases

in Pediatric Endocrinology

Jiaxing Du
Keze Ma
Zhiwei Ye
Juanli Song
Sujun Chen
Zhenlin Xiong
Weinan Zheng
Meifei Li
Huiyi Yu
Fen Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1598262

2,027 views

Case Report

Published on 25 Sep 2025

Case Report: Exaggerated estradiol secretion in an infant with hypothalamic hamartoma

in Pediatric Endocrinology

Maja Vinkovic
Duje Braovac
Katja Dumic Kubat
Ivan Jovanovic
Maja Banovic
Nevena Krnic

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1598734

1,559 views

Original Research

Published on 25 Sep 2025

Can the triglyceride–glucose index identify prediabetes in children and adolescents with obesity? a cross-sectional study

in Pediatric Endocrinology

Hongxia Liu
Luxin Wang
Xinyu Zhu
Yan Wang
Bo Zhang
Caixia Ma
Li Gao
Jinming Yu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1657912

2,259 views
1 citation

Case Report

Published on 25 Sep 2025

Case Report: Food-based enteral formula in the nutritional management of children with hyperinsulinism: single center retrospective case series

in Pediatric Endocrinology

Graeme O’Connor
Lauren Cheng
Annaruby Cunjamalay

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1574093

1,856 views

Original Research

Published on 25 Sep 2025

Diagnostic and therapeutic pitfalls in the management of pediatric patients with 3β-hydroxysteroid dehydrogenase type 2 (3β-HSD2) deficiency - a single center experience

in Pediatric Endocrinology

Zuzanna Gawlik
Ewelina Preizner-Rzucidło
Konrad Kaleta
Maria Szwarkowska
Martyna Wróblewska
Aleksandra Jurek
Teofila Książek
Krystian Jażdżewski
Anna Siejka
Jerzy Starzyk

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1642051

2,688 views

Original Research

Published on 19 Sep 2025

12-month outcomes of GLP - 1 in severe pediatric obesity: real-world data

in Pediatric Endocrinology

Louise Cominato
Mariana L. Resende
Natalia Bernardes
Ludmila L. Rachid
Caroline G. B. Passone
Larissa B. F. Mattar
Georgia Neme
Sarah G. Souza
Claudia Renata P. Santos
Ruth R. Franco

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1663499

3,645 views
2 citations

967 articles

articles

Exosomal miRNAs as potential biomarkers for insulin resistance and metabolic dysfunction-associated steatotic liver disease in children with obesity

Editorial: Perinatal and post-natal life: metabolism and health outcomes

Bile acids: potential links to overweight/obesity and androgen levels in pubertal girls

Metabolic factors influencing the efficacy of recombinant human growth hormone therapy in children with short stature

PNPLA3-Ile148Met and TM6SF2-Glu167Lys increase susceptibility to metabolic dysfunction-associated steatotic liver disease in children

Pharmacological and non-pharmacological modulation of endoplasmic reticulum stress in pediatric diabetes

Food responsiveness, addiction, and hyperphagia in Prader-Willi syndrome: a cross-sectional study of 210 Chinese patients

Growth hormone therapy and chromosomal mosaicism in turner syndrome: 25 years of growth outcomes in Taiwan

Editorial: Interplay of genetics and environment in pediatric diabetes: insights and innovations

First description of co-occurrence of 49,XXXXY and X-linked Cornelia de Lange syndrome: case report

Comprehensive characterization of 21-hydroxylase deficiency in a Chinese pediatric cohort: phenotype, steroid profiles and genetics

Differences in growth in prepubertal children with definite growth hormone deficiency, short stature unresponsive to stimulation tests, and idiopathic short stature treated with recombinant human growth hormone: a retrospective study

The role of digital health in growth hormone therapy: perspectives from Gulf Cooperation Council pediatric endocrinologists

Case Report: Autoimmune polyglandular syndrome type 4 involving diabetes mellitus type 1, autoimmune hepatitis, immune thrombocytopenia, and celiac disease

Utility of continuous glucose monitoring for identifying silent hypoglycemia in fructose-1,6-bisphosphatase deficiency: a pilot prospective evaluation

Efficacy of combined gonadotropin-releasing hormone analogue and growth hormone therapy in girls with central precocious puberty: a systematic review and meta-analysis

Brain structural changes in girls with idiopathic central precocious puberty: a voxel-based morphometry and surface-based morphometry analysis

Insulin resistance, metabolic syndrome and polycystic ovaries: an intriguing conundrum

U-shaped association between triglyceride-glucose index and acute kidney injury in critically ill children with cardiac diseases

Case Report: Exaggerated estradiol secretion in an infant with hypothalamic hamartoma

Can the triglyceride–glucose index identify prediabetes in children and adolescents with obesity? a cross-sectional study

Case Report: Food-based enteral formula in the nutritional management of children with hyperinsulinism: single center retrospective case series

Diagnostic and therapeutic pitfalls in the management of pediatric patients with 3β-hydroxysteroid dehydrogenase type 2 (3β-HSD2) deficiency - a single center experience

12-month outcomes of GLP - 1 in severe pediatric obesity: real-world data