Frontiers in Immunology

Original Research

Published on 02 Dec 2025

Immunomodulatory and anti-inflammatory effects of agave fructans in atopic dermatitis: gut microbiota and short-chain fatty acid implication

in Nutritional Immunology

Marcela Rios-Carlos
Mariela Jiménez
Daniel Cervantes-García
Laura Elena Córdova-Dávalos
Lidia E. Verduzco
Francisco Javier Enríquez-Medrano
Omar Fabela-Sánchez
Luis G. Bermúdez-Humarán
Eva Salinas

Frontiers in Immunology

doi 10.3389/fimmu.2025.1700023

865 views

Brief Research Report

Published on 02 Dec 2025

Daratumumab combined with anti-CD20 therapy in pediatric and adult refractory idiopathic nephrotic syndrome: single-center experience

in Alloimmunity and Transplantation

Hamza Naciri Bennani
Thomas Sandaye
Quentin Charroyer
Aurelie Etangsale
Henri Vacher Coponat
Marie Julien
Vincent Mear
Olivier Dunand
Ludovic Di Ascia

Frontiers in Immunology

doi 10.3389/fimmu.2025.1722023

649 views

Case Report

Published on 02 Dec 2025

Case Report: Pseudoprogression of pancreatic acinar cell carcinoma after PD-1 blockade integrated treatment

in Cancer Immunity and Immunotherapy

Xinyuan Bai
Di Yang
Jingjing Chen
Yaru Liu
Haochen Tang
Xiang Kong
Baorui Liu
Huizi Sha
Juan Du

Frontiers in Immunology

doi 10.3389/fimmu.2025.1663514

628 views

Original Research

Published on 02 Dec 2025

Targeting PSMB5-induced PANoptosis in bladder cancer: multi-omics insights and TCM candidate discovery

in Cancer Immunity and Immunotherapy

Zhe Chang
Jirong Wang
Jiajia Cao
Xinpeng Fan
Kunpeng Li
Chenyang Wang
Yalong Zhang
Li Wang
Jianwei Yang
Siyu Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1656682

774 views

Original Research

Published on 02 Dec 2025

Expression characteristics, prognostic value, and immune-related analysis of PPP2R1A in lung adenocarcinoma

in Cancer Immunity and Immunotherapy

Shanshan Xiao
Yuhong Hu
Yawen Li
Xin Zhang
Zijun Xiao
Mingyou Dong
Lusheng Liao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1652629

741 views

Correction

Published on 02 Dec 2025

Correction: Generation of a new Paneth cell-specific Cre-recombinase transgenic mouse line

in Microbial Immunology

Natalia Garcia-Gonzalez
Charlotte Wallaeys
Wendy Toussaint
Tino Hochepied
Sylviane Dewaele
Somara De Beul
Robin Van Loke
Jolien Vandewalle
Steven Timmermans
Richard S. Blumberg

Frontiers in Immunology

doi 10.3389/fimmu.2025.1733126

249 views

Original Research

Published on 02 Dec 2025

Predictive value of current nodal staging systems and development of machine learning nomogram for resectable pancreatic head cancer: a population-based study and multicenter validation

in Cancer Immunity and Immunotherapy

Wen-Bo Zou
Xiu-Ping Zhang
Yu-Yao Song
Shuai Xu
Bo-Yuan Liu
Zhi-Ming Zhao
Yuan-Xing Gao
Ming-Gen Hu
Gao Huang
Rong Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1639186

515 views

Original Research

Published on 02 Dec 2025

Serum and urine anti-PLA2R antibody correlation with albuminuria in idiopathic membranous nephropathy

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Xiaogang Liu
Yunfei Fu
Manshu Sui
Xuehua Wang
Zizhen Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1670960

494 views

Methods

Published on 02 Dec 2025

Rotavirus-specific neutralization assay enables evaluation of mucosal immune responses

in Mucosal Immunity

Maxi Harzer
Antje Rückner
Thomas W. Vahlenkamp

Frontiers in Immunology

doi 10.3389/fimmu.2025.1677823

665 views

Original Research

Published on 02 Dec 2025

Unraveling the anti-inflammatory effects of Mediterranean diet in patients with cancer remission

in Inflammation

Michele Francesco Di Tolla
Michele Libutti
Giovanna D’Onofrio
Alessandra Riccio
Serena Cabaro
Michele Longo
Alessia Parascandolo
Giusy Ferraro
Elia Formisano
Vittoria D’Esposito

Frontiers in Immunology

doi 10.3389/fimmu.2025.1666611

1,295 views

Original Research

Published on 02 Dec 2025

Serum profiling of uPA, PAI-1, and suPAR in systemic sclerosis: a preliminary study on analytical aspects and associations with microvascular and fibrotic manifestations

in Cytokines and Soluble Mediators in Immunity

Filomena Napolitano
Ilaria Mormile
Gabriele Mignogna
Amato de Paulis
Francesca Wanda Rossi
Nunzia Montuori

Frontiers in Immunology

doi 10.3389/fimmu.2025.1697785

651 views

Review

Published on 02 Dec 2025

The new era of immunotherapy for breast cancer: challenges and coping strategies of CAR-T cell therapy

in Cancer Immunity and Immunotherapy

Zhihao Wang
Lele Miao
Wei Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1698146

816 views

Original Research

Published on 02 Dec 2025

Epigenetic activation of CD274/PD-L1 by the MSL complex expands its role beyond dosage compensation

in Cancer Immunity and Immunotherapy

Aiping Wen
Xuanfei Feng
Yingying Li
Xueli Cui
Qixian Zou
Yong Cai
Jingji Jin
Yunxiao He

Frontiers in Immunology

doi 10.3389/fimmu.2025.1711451

783 views

Review

Accepted on 01 Dec 2025

The role of interleukins in peripheral nerve injury and the current status of treatment

in Cytokines and Soluble Mediators in Immunity

悦沈
Li Mingzhu
圣博金
子洋喻
倩刘
Huini Yao
Yuxin Jiang
佳晴付
Ningxin Li李

Frontiers in Immunology

116 views

Review

Accepted on 01 Dec 2025

TWEAK-Fn14: A promising target for cardio-cerebrovascular diseases and brain-heart syndrome

in Comparative Immunology

Qinglin Fei
Chang Jun
Tingcan Jiang
Guoqiang Guan
Yujuan Liang
Cuicui Cheng
Guangxu Xiao
Qiuyan Guo
Guanwei Fan
Yan Zhu

Frontiers in Immunology

107 views

Original Research

Accepted on 01 Dec 2025

Neisseria bacilliformis is a periodontal pathogen exacerbating periodontitis by inducing nitric oxide production

in Microbial Immunology

Bo-Min Kim
Yeonjin Lim
Somin Park
Jintaek Im
Cheol-Heui YUN
Kee-Yeon Kum
Ok-Jin Park
Seung Hyun Han

Frontiers in Immunology

204 views

Review

Accepted on 01 Dec 2025

Multi-Omics Reveals Circadian Regulation of Bone Homeostasis by Gut Microbiota Metabolites: Mechanisms and Chronotherapeutic Implications

in Microbial Immunology

Mingdong Liu
Jiaqi Gong
Yaqi Liu
Jiayao Yu
Zepeng Hu
Zheng Liu

Frontiers in Immunology

119 views

Original Research

Accepted on 01 Dec 2025

The Neoadjuvant Esophageal (NAE) Score: A Prognostic Tool for Predicting Survival and Postoperative Complications in Esophageal Squamous Cell Carcinoma

in Cancer Immunity and Immunotherapy

Hao Chen
Xuan Huang
Cheng Huang
Qichang Xie
Chun Chen
Bin Zheng
Yuxing Lin
Renjie Huang
Li Cheng
Chi Xu

Frontiers in Immunology

105 views

Original Research

Accepted on 01 Dec 2025

Pilot Proteomic Analysis of Immune Dysregulation in Dengue with Prior SARS-CoV-2 Infection

in Viral Immunology

Elizabeth Cruz-Altamirano
Miguel-Angel Mayoral
Luis Román Ramírez-Palacios
Luz Maria Quirino-Vela
Diego Sait Cruz-Hernández
Sergio Aguilar
Juan Alpuche

Frontiers in Immunology

176 views

Original Research

Accepted on 01 Dec 2025

Exploring the impact of age, sex and life experiences on plasma inflammatory profiles through comparative proteomics

in Inflammation

Maddalena Mastrogiacomo
Martina Bartolucci
Olga Utyro
Anita Muraglia
Alessia Repetto
Vanessa Agostini
Monica Pizzonia
Silvia Ottaviani
Gilberto Filaci
Ranieri Cancedda

Frontiers in Immunology

245 views

Original Research

Accepted on 01 Dec 2025

Hepatic Zinc Deficiency Dampens the Acute Phase Response in Patients with Alcohol-Associated Hepatitis

in Nutritional Immunology

Scott A Read
Mehdi Ramezani Moghadam
Brian Gloss
Romario Nguyen
Benjamin Woodham
Vincent Lam
Lawrence Yuen
Jimin Yoon
Liang Qiao
Thomas Tu

Frontiers in Immunology

194 views

Original Research

Published on 01 Dec 2025

Commensal Staphylococci attenuate Staphylococcus aureus skin colonization and inflammation via AHR-dependent signaling

in Microbial Immunology

Jule Riebelmann
Nicole Kienzle
Birgit Sauer
Birgit Schittek

Frontiers in Immunology

doi 10.3389/fimmu.2025.1726557

888 views

Mini Review

Published on 01 Dec 2025

Decoding m6A readers: roles of YTHDF proteins in leukemogenesis and cancer immunity

in Cancer Immunity and Immunotherapy

Chunhong Li
Xi Chen
Shanrui Pu
Kun Lian
Lihua Li
Xiulin Jiang
Qiang Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1692608

594 views

Original Research

Published on 01 Dec 2025

Causality of circulating vitamins on infectious diseases: integrating Mendelian randomization and in vivo evidence

in Microbial Immunology

Aling Tang
Zhimin Gong
Yi Shi
Weizhen Zhang
Mingming Jin
Lichao Sun
Wei Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1674678

806 views

48,462 articles

articles

Immunomodulatory and anti-inflammatory effects of agave fructans in atopic dermatitis: gut microbiota and short-chain fatty acid implication

Daratumumab combined with anti-CD20 therapy in pediatric and adult refractory idiopathic nephrotic syndrome: single-center experience

Case Report: Pseudoprogression of pancreatic acinar cell carcinoma after PD-1 blockade integrated treatment

Targeting PSMB5-induced PANoptosis in bladder cancer: multi-omics insights and TCM candidate discovery

Expression characteristics, prognostic value, and immune-related analysis of PPP2R1A in lung adenocarcinoma

Correction: Generation of a new Paneth cell-specific Cre-recombinase transgenic mouse line

Predictive value of current nodal staging systems and development of machine learning nomogram for resectable pancreatic head cancer: a population-based study and multicenter validation

Serum and urine anti-PLA2R antibody correlation with albuminuria in idiopathic membranous nephropathy

Rotavirus-specific neutralization assay enables evaluation of mucosal immune responses

Unraveling the anti-inflammatory effects of Mediterranean diet in patients with cancer remission

Serum profiling of uPA, PAI-1, and suPAR in systemic sclerosis: a preliminary study on analytical aspects and associations with microvascular and fibrotic manifestations

The new era of immunotherapy for breast cancer: challenges and coping strategies of CAR-T cell therapy

Epigenetic activation of CD274/PD-L1 by the MSL complex expands its role beyond dosage compensation

The role of interleukins in peripheral nerve injury and the current status of treatment

TWEAK-Fn14: A promising target for cardio-cerebrovascular diseases and brain-heart syndrome

Neisseria bacilliformis is a periodontal pathogen exacerbating periodontitis by inducing nitric oxide production

Multi-Omics Reveals Circadian Regulation of Bone Homeostasis by Gut Microbiota Metabolites: Mechanisms and Chronotherapeutic Implications

The Neoadjuvant Esophageal (NAE) Score: A Prognostic Tool for Predicting Survival and Postoperative Complications in Esophageal Squamous Cell Carcinoma

Pilot Proteomic Analysis of Immune Dysregulation in Dengue with Prior SARS-CoV-2 Infection

Exploring the impact of age, sex and life experiences on plasma inflammatory profiles through comparative proteomics

Hepatic Zinc Deficiency Dampens the Acute Phase Response in Patients with Alcohol-Associated Hepatitis

Commensal Staphylococci attenuate Staphylococcus aureus skin colonization and inflammation via AHR-dependent signaling

Decoding m6A readers: roles of YTHDF proteins in leukemogenesis and cancer immunity

Causality of circulating vitamins on infectious diseases: integrating Mendelian randomization and in vivo evidence