Frontiers in Immunology

Correction

Published on 21 Aug 2025

Correction: RG100204, a novel Aquaporin-9 inhibitor, reduces septic cardiomyopathy and multiple organ failure in murine sepsis

in Inflammation

Shireen Mohammad
Caroline E. O’Riordan
Chiara Verra
Eleonora Aimaretti
Gustavo Ferreira Alves
Klaus Dreisch
Johan Evenäs
Patrizia Gena
Angela Tesse
Michael Rützler

Frontiers in Immunology

doi 10.3389/fimmu.2025.1672460

1,429 views

Original Research

Published on 21 Aug 2025

The critical role of matrix metalloproteinase 9-mediated microglial polarization in perioperative neurocognitive disorders of aged rats

in Inflammation

Xi Xin
Haonan Zhang
Chenyi Yang
Xinyi Wang
Lin Zhang
Ji Ma
Haiyun Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1650254

2,384 views

Review

Published on 20 Aug 2025

Mesenchymal stromal cells 2.0: thinking outside the box

in Inflammation

Gabrielle A. Mandl
Malak Lahrichi
Perla Matar
Jamilah Abusarah
Roudy Farah
Jean Pierre Bikorimana
Abba Cisse
Moutih Rafei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1657048

2,947 views

Original Research

Published on 20 Aug 2025

Analysis and validation of diagnostic biomarkers and immune cell infiltration characteristics in osteoarthritis by integrating bioinformatics and machine learning

in Inflammation

Tianyang Li
Jinpeng Wei
Hua Wu
Chen Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1596912

3,919 views

Original Research

Published on 20 Aug 2025

Identification of cuproptosis-related genes in chronic apical periodontitis based on bulk and single-cell RNA sequencing analyses and experimental validation

in Inflammation

Caiyi Zhang
Jie Zhao
Keqing Pan
Lingshuang Liu
Mengyu Jiao
Changqing Yuan
Chunyan Wan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1559220

3,614 views

Original Research

Published on 20 Aug 2025

Identification of sepsis biomarkers through glutamine metabolism-mediated immune regulation: a comprehensive analysis employing mendelian randomization, multi-omics integration, and machine learning

in Inflammation

Zhuang’e Shi
Fuping Wang
Lishun Yang
Couwen Li
Bing Gong
Ruanxian Dai
Guobing Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1640425

5,419 views

Mini Review

Published on 20 Aug 2025

The dual nature of neuroinflammation in networked brain

in Inflammation

Ludmila Müller
Svetlana Di Benedetto
Viktor Müller

Frontiers in Immunology

doi 10.3389/fimmu.2025.1659947

4,428 views
6 citations

Correction

Published on 20 Aug 2025

Correction: Single-cell and spatial transcriptomics reveal a stress-induced EMT-like epithelial subset driving immune activation in silica-injured lung

in Inflammation

Tao Wang
Jianfeng Hao
Bing Li
Ahjol Hyraht
Jialing Wang
Henglei Xia
Qingbin Wu
Wei Gao
Congxia Chen
Chuanqing Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1671133

1,526 views

Brief Research Report

Published on 19 Aug 2025

NINJ1 oligomerises on large apoptotic cell-derived extracellular vesicles to regulate vesicle stability and cellular content release

in Inflammation

Bo Shi
Caolingzhi Tang
Stephanie F. Rutter
Omar Audi
Dilara C. Ozkocak
Alice M. Trenerry
Daniel S. Simpson
Scott A. Williams
Quan T. Le
Gemma F. Ryan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1599809

3,981 views

Original Research

Published on 19 Aug 2025

HNF4α contributes to hepatic CAR dysfunction in polymicrobial sepsis

in Inflammation

Céline Van Dender
Steven Timmermans
Maxime Roes
Madeleine Hellemans
Elise Moens
Louise Nuyttens
Maarten Claes
Bart Roman
Karolien De Bosscher
Jolien Vandewalle

Frontiers in Immunology

doi 10.3389/fimmu.2025.1625104

3,126 views

Review

Published on 18 Aug 2025

Targeting E3 ubiquitin ligases: a new frontier in idiopathic pulmonary fibrosis treatment

in Inflammation

Kun Zhang
Hui Yuan
Lin Shi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1618424

3,660 views
2 citations

Mini Review

Published on 15 Aug 2025

Ferroptosis-immune crosstalk in cervical cancer: mechanisms and therapeutic implications

in Inflammation

Lili Li
Yunfeng Bo
Dan Xue
Lijuan Qin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1657905

4,190 views
1 citation

Original Research

Published on 15 Aug 2025

An exploratory single-cell analysis of peripheral blood mononuclear cells from vedolizumab-treated Crohn’s disease patients identifies response-associated differences among the plasmacytoid dendritic cells and classical monocytes

in Inflammation

Andrew Yung Fong Li Yim
Ishtu Hageman
Vincent W. Joustra
Ahmed M. I. M. Elfiky
Mohammed Ghiboub
Evgeni Levin
Jan Verhoeff
Caroline Verseijden
Iris Admiraal
Manon de Krijger

Frontiers in Immunology

doi 10.3389/fimmu.2025.1551017

3,777 views

Original Research

Published on 15 Aug 2025

IL-17-neutralizing antibody mitigates functional and structural changes in cigarette smoke-induced COPD model

in Inflammation

Alyne Riani Moreira
Camila Uchoa da Silva
Leticia de Paula Costa Mattos
Jussara Jesus Simão
Veronica Camargo Berti
Luan Henrique Vasconcelos Alves
Alex Ferreira da Silva
Franciele Jesus Lima
Suellen Karoline Moreira Bezerra
Cintia Nascimento Silva

Frontiers in Immunology

doi 10.3389/fimmu.2025.1641300

2,525 views

Correction

Published on 15 Aug 2025

Correction: Chitinase-1 inhibition attenuates metabolic dysregulation and restores homeostasis in MASH animal models

in Inflammation

Frontiers Production Office

Frontiers in Immunology

doi 10.3389/fimmu.2025.1680129

924 views

Original Research

Published on 15 Aug 2025

Pharmacological inhibition of IL12β is effective in treating pressure overload-induced cardiac inflammation and heart failure

in Inflammation

Umesh Bhattarai
Xiaochen He
Ziru Niu
Lihong Pan
Dongzhi Wang
Hao Wang
Heng Zeng
Jian-Xiong Chen
Joshua S. Speed
John S. Clemmer

Frontiers in Immunology

doi 10.3389/fimmu.2025.1624940

2,598 views
1 citation

Original Research

Published on 15 Aug 2025

SHP2 inhibition by SHP099 attenuates IL-6–driven osteoclastogenesis in growth plate injury

in Inflammation

Qin Zhang
Ning Li
Zhen-Zhen Dai
Xiao-Man Liu
Jing Ding
Lin Sha
Hai Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1659230

2,303 views

Original Research

Published on 14 Aug 2025

Abnormal lipid metabolism and atherosclerosis: a new perspective on organelle function regulation and ferroptosis

in Inflammation

Xize Wu
Yuxi Huang
Jiaqi Ren
Xue Pan
Qiuying Wu
Qicheng Cai
Ruiying Wang
Teng Feng
Shan Gao
Bo Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1642984

5,217 views

Original Research

Published on 14 Aug 2025

Developing and validating anti-ADA2 single-chain antibodies coupled to alkaline phosphatase for diagnosing pleural tuberculosis

in Inflammation

Maksym Skaldin
José M. Porcel
Urpo Lamminmäki
Silvia Bielsa
Andrey V. Zavialov

Frontiers in Immunology

doi 10.3389/fimmu.2025.1646134

2,107 views
1 citation

Systematic Review

Published on 14 Aug 2025

Effects of different exercise prescription parameters on metabolic and inflammatory biomarkers in cancer patients: a systematic review, meta-analysis, and meta-regression

in Inflammation

Jingyu Wang
Yuxuan He
Ziqian Wang
Zhouluo Wang
Yongqi Miao
Jae-Young Choi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1663560

5,259 views
4 citations

Review

Published on 14 Aug 2025

Therapeutic frontiers in viral myocarditis: targeting inflammation, viruses, oxidative stress, and myocardial repair

in Inflammation

Jingyao Xu
Xuanjia Chen
Xia Guan
Haiying Zhang
Yan Liu
Min Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1643502

4,321 views
2 citations

Original Research

Published on 13 Aug 2025

Distinct NK cell function and gene expression in children with acute lymphoblastic leukemia in remission before and after acute exercise: an exploratory study

in Inflammation

Abel Plaza-Florido
Martin Perlsteyn
Fadia Haddad
Dan M. Cooper
Ronen Bar-Yoseph
Alejandro Lucia
Shlomit Radom-Aizik

Frontiers in Immunology

doi 10.3389/fimmu.2025.1625437

2,615 views

Review

Published on 13 Aug 2025

Immunological mechanisms in steroid-induced osteonecrosis of the femoral head

in Inflammation

Zhilei Yin
Longfei Wu
Jiwei Huang
Haiyan Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1626617

3,849 views
2 citations

Original Research

Published on 13 Aug 2025

Identification of novel hub genes and pathways predictive of fibrosis progression in cancer-related lymphedema through integrated multi-omics

in Inflammation

Junzhe Chen
Yuezhong Chen
Liangliang Wang
Yaping Deng
Yan Zhou
Yun Wang
Shune Xiao
Chengliang Deng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1625972

3,440 views
1 citation

5,790 articles

articles

Correction: RG100204, a novel Aquaporin-9 inhibitor, reduces septic cardiomyopathy and multiple organ failure in murine sepsis

The critical role of matrix metalloproteinase 9-mediated microglial polarization in perioperative neurocognitive disorders of aged rats

Mesenchymal stromal cells 2.0: thinking outside the box

Analysis and validation of diagnostic biomarkers and immune cell infiltration characteristics in osteoarthritis by integrating bioinformatics and machine learning

Identification of cuproptosis-related genes in chronic apical periodontitis based on bulk and single-cell RNA sequencing analyses and experimental validation

Identification of sepsis biomarkers through glutamine metabolism-mediated immune regulation: a comprehensive analysis employing mendelian randomization, multi-omics integration, and machine learning

The dual nature of neuroinflammation in networked brain

Correction: Single-cell and spatial transcriptomics reveal a stress-induced EMT-like epithelial subset driving immune activation in silica-injured lung

NINJ1 oligomerises on large apoptotic cell-derived extracellular vesicles to regulate vesicle stability and cellular content release

HNF4α contributes to hepatic CAR dysfunction in polymicrobial sepsis

Targeting E3 ubiquitin ligases: a new frontier in idiopathic pulmonary fibrosis treatment

Ferroptosis-immune crosstalk in cervical cancer: mechanisms and therapeutic implications

An exploratory single-cell analysis of peripheral blood mononuclear cells from vedolizumab-treated Crohn’s disease patients identifies response-associated differences among the plasmacytoid dendritic cells and classical monocytes

IL-17-neutralizing antibody mitigates functional and structural changes in cigarette smoke-induced COPD model

Correction: Chitinase-1 inhibition attenuates metabolic dysregulation and restores homeostasis in MASH animal models

Pharmacological inhibition of IL12β is effective in treating pressure overload-induced cardiac inflammation and heart failure

SHP2 inhibition by SHP099 attenuates IL-6–driven osteoclastogenesis in growth plate injury

Abnormal lipid metabolism and atherosclerosis: a new perspective on organelle function regulation and ferroptosis

Developing and validating anti-ADA2 single-chain antibodies coupled to alkaline phosphatase for diagnosing pleural tuberculosis

Effects of different exercise prescription parameters on metabolic and inflammatory biomarkers in cancer patients: a systematic review, meta-analysis, and meta-regression

Therapeutic frontiers in viral myocarditis: targeting inflammation, viruses, oxidative stress, and myocardial repair

Distinct NK cell function and gene expression in children with acute lymphoblastic leukemia in remission before and after acute exercise: an exploratory study

Immunological mechanisms in steroid-induced osteonecrosis of the femoral head

Identification of novel hub genes and pathways predictive of fibrosis progression in cancer-related lymphedema through integrated multi-omics